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Clyde E. Markowitz, MD

Clyde E. Markowitz, MD Physician

Director, Multiple Sclerosis Center at Penn Associate Professor of Neurology at the Hospital of the University of Pennsylvania

Dr. Markowitz is employed by Penn Medicine.

About Dr. Clyde E. Markowitz

Recognized by America's Top Doctors 2015 – 2017

Recognized by Best Doctors in America 2015 - 2018

Recognized in Philadelphia magazine's May 2018 Top Docs issue



Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties


  • Neurology

Programs & Centers:

Board Certification:

  • Neurology, 1995

Clinical Expertise:

  • Multiple Sclerosis (MS)
  • Neuroimmunology

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Columbia University
Residency: NewYork-Presbyterian/Columbia University Medical Center
Fellowship: NewYork-Presbyterian/Columbia University Medical Center


American Academy of Neurology, National American Academy of Neurology, National Bayer Healthcare, International Biogen-Idec, International BioMS, International Bristol Meyers Squib, International EMD Serono, International Genentech, International International Multiple Sclerosis Forum, International Multiple Sclerosis Cooperative Research Group (MS-CORE), National National Multiple Sclerosis Society, Delaware Valley Chapter, Local Novartis, International Penn Neuro Care-MS Section, Local Pfizer, International Teva Neuroscience, International Wyeth, International

Hospital Affiliation

Dr. Markowitz is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Selected Publications:

Salim Chahin, MD; Deborah Miller, PhD; Reiko Sakai; James Wilson; Clyde Markowitz, MD; Dina Jacobs, MD; Ari Green, MD; Peter A. Calabresi, MD; Elliot M. Frohman, MD; Steven Galetta, MD; Laura Balcer, MD, MSCE:: Fatigue in Multiple Sclerosis: Relation to Quantitative Neurologic and Visual Outcomes. Multiple Sclerosis and related disorders : 2015.

Jose Torres, Amy Pruitt, Laura Balcer, Steven Galetta, Clyde Markowitz, Nabila Dahodwala: Analysis of the treatment of neuromyelitis optica Journal of the Neurological Sciences 351 (1): 2015.

Salim Chahin, Deborah Miller, Reiko E. Sakai, James A. Wilson, Teresa Frohman, Clyde Markowitz, Dina Jacobs, Ari Green, Peter A. Calabresi, Elliot M. Frohman, Steven L. Galetta, Laura J. Balcer: Relation of quantitative Visual and neurologic outcomes to fatigue in multiple sclerosis Multiple Sclerosis and Related Disorders 4 (4): 2015.

Edward Fox, Barbara Green, Clyde Markowitz, Ronald Murray, Andrew D Goodman, Stephen J Glenski, Pippa Loupe, Jo Nita Cogburn: The effect of scheduled antibody testing on treatment patterns in interferon-treated patients with multiple sclerosis BMC Neurology 14 (1): 2014.

Patricia K Coyle, Bruce A Cohen, Thomas Leist, Clyde Markowitz, Merrikay Oleen-Burkey, Marc Schwartz, Mark J Tullman, Howard Zwibel: Therapy optimization in multiple sclerosis: a prospective observational study of therapy compliance and outcomes BMC Neurology 14 (1): 2014.

Miller Aaron E, Cohen Bruce A, Krieger Stephen C, Markowitz Clyde E, Mattson David H, Tselentis Helen N: Constructing an adaptive care model for the management of disease-related symptoms throughout the course of multiple sclerosis--performance improvement CME. Multiple sclerosis (Houndmills, Basingstoke, England) : 2013.

Oh Se-Hong, Bilello Michel, Schindler Matthew, Markowitz Clyde E, Detre John A, Lee Jongho: Direct visualization of short transverse relaxation time component (ViSTa). NeuroImage 83C : 485-492,2013.

Fox Edward, Wynn Daniel, Cohan Stanley, Rill Donna, McGuire Dawn, Markowitz Clyde: A randomized clinical trial of autologous T-cell therapy in multiple sclerosis: subset analysis and implications for trial design. Multiple sclerosis (Houndmills, Basingstoke, England) 18 (6): 843-52,2012.

Dhib-Jalbut S, Markowitz C, Patel P, Boateng F, Rametta M: The Combined Effect of Nursing Support and Adverse Event Mitigation on Adherence to Interferon Beta-1b Therapy in Early Multiple Sclerosis International Journal of MS Care 14 (4): 198-208,2012.

Schelleman Hedi, Pollard John R, Newcomb Craig, Markowitz Clyde E, Bilker Warren B, Leonard Mary B, Hennessy Sean: Exposure to CYP3A4-inducing and CYP3A4-non-inducing antiepileptic agents and the risk of fractures. Pharmacoepidemiology and drug safety 20 (6): 619-25,2011.

Academic Contact Info

Hospital of the University of Pennsylvania
3 West Gates Building
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 662-4521
Patient appointments: 800-789-7366 (PENN)

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