- Multiple sclerosis
Clyde E. Markowitz, MD
About me
- Director, Multiple Sclerosis Center at Penn
- Associate Professor of Neurology at the Hospital of the University of Pennsylvania
My education and training
- Medical School: Columbia University
- Residency: NewYork–Presbyterian Hospital
- Fellowship: NewYork-Presbyterian/Columbia University Medical Center
Spoken languages
Reviews
847 reviews
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Insurance accepted
- Aetna Advantra Cares D-SNP
- Aetna Advantra Credit Value
- Aetna Advantra Eagle HMO
- Aetna Advantra Eagle POS
- Aetna Advantra Premier Plus PPO
- Aetna Advantra Value
- Aetna Advantra Value Plus
- Aetna APCN Plus (Multi-Tier)
- Aetna Better Health Kids (CHIP) - DH Only
- Aetna Flexible Five
- Aetna Freedom Core
- Aetna Gold
- Aetna HMO
- Aetna Philly Prime
- Aetna POS
- Aetna PPO APCN
- Aetna Premier
- Aetna Premier Plus
- Aetna Savings Plus
- Aetna Signature Administrators
- Aetna Student Health Plan PPO
- Aetna Upfront Advantage
- First Health HMO
- First Health POS
- First Health PPO
- Meritain - Aramark (Other)
- Meritain - Aramark (Pennsylvania Premier Medical Plan)
- Centivo EPO
- Cigna Healthcare EPO
- Cigna Healthcare HMO
- Cigna Healthcare POS
- Cigna Healthcare PPO
- Claim Watcher (Homestead/ INDECs) Open Access
- Clover Health Choice
- Clover Health Choice Value PPO
- Clover Health Classic HMO
- Clover Health Value
- Devoted Health Choice Giveback Pennsylvania (PPO)
- Devoted Health Choice Pennsylvania (PPO)
- Devoted Health Choice Plus Pennsylvania (PPO)
- Devoted Health Core Pennsylvania (HMO)
- Devoted Health Dual Plus Pennsylvania (HMO D-SNP)
- Devoted Health Giveback Pennsylvania (HMO)
Locations
Penn Medicine hospital privileges
- Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
- Pennsylvania Hospital: Has privileges to treat patients in the hospital.
- Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Qualifications and experience
- Neurology, 1995
- American Academy of Neurology, National
- American Academy of Neurology, National
- Bayer Healthcare, International
- Biogen-Idec, International
- BioMS, International
- Bristol Meyers Squib, International
- EMD Serono, International
- Genentech, International
- International Multiple Sclerosis Forum, International
- Multiple Sclerosis Cooperative Research Group (MS-CORE), National
- National Multiple Sclerosis Society, Delaware Valley Chapter, Local
- Novartis, International
- Penn Neuro Care-MS Section, Local
- Pfizer, International
- Teva Neuroscience, International
- Wyeth, International
- Recognized annually in Philadelphia Magazine's Top Docs issue from 2018 through 2025
Treatments and conditions
Research
Publications
Miller TM, Cudkowicz ME, Shaw PJ, Genge A, Sobue G, Bucelli RC, Chiò A, Van Damme P, Ludolph AC, Glass JD, Andrews JA, Babu S, Benatar M, McDermott CJ, Salachas F, Bruneteau G, Al-Chalabi A, Amorin M, Nestorov I, Graham D, Lin L, Sun P, McNeill M, Malek S, Inra J, Garafalo S, Fradette S; VALOR and OLE Working Group. Long-Term Tofersen in SOD1 Amyotrophic Lateral Sclerosis , JAMA Neurol, 83: 2026,115-125
Simon Thebault, Samantha Soldan, Gautier Breville, Luana Yamashita, Elia Afanasiev, jo Anne stratton, Christopher Perrone, Clyde Markowitz, Paul Lieberman, Amit Bar-Or "Immunophenotypic characterisation of EBV-infected B cells in MS blood and CSF using PrimeFlow" , ECTRIMS 2025, Barcelona , Spain , 31(3): 2025
Naydovich LR, Orthmann-Murphy JL, Markowitz CE. Beyond relapses: How BTK inhibitors are shaping the future of progressive MS treatment , Neurotherapeutics, 22 (4): 2025
Cooper EC, Schindler MK, Bar-Or A, Brandstadter RB, Calkins ME, Gur R, Jacobs DA, Markowitz C, Moore T, Naydovich LR, Perrone CM, Ruparel K, Spangler BC, Troyan S, Shinohara RT, Satterthwaite TD, Baller EB. Investigating mood and cognition in people with multiple sclerosis: a prospective cross-sectional study protocol , BMJ Open, 15: 2025,e094733
Martin ML, Robert-Fitzgerald T, Schindler MK, Perrone C, Schultz G, Lynch S, Mirkovic N, Thomas S, Elahi A, Reid D, Moore TM, Baller EB, Satterthwaite TD, Cieslak M, Covitz S, Adebimpe A, Manning A, Markowitz CE, Detre JA, Bar-Or A, Kakara M, Shinohara RT. Impact of insurance status on MRI phenotypes in MS , Mult Scler Relat Disord: 2024
Baller EB, Sweeney EM, Cieslak M, Robert-Fitzgerald T, Covitz SC, Martin ML, Schindler MK, Bar-Or A, Elahi A, Larsen BS, Manning AR, Markowitz CE, Perrone CM, Rautman V, Seitz MM, Detre JA, Fox MD, Shinohara RT, Satterthwaite TD. Mapping the Relationship of White Matter Lesions to Depression in Multiple Sclerosis , Biol Psychiatry, 95: 2024,1072-1080
Coyle PK, Freedman MS, Cohen BA, Cree BAC, Markowitz CE. Sphingosine 1-phosphate receptor modulators in multiple sclerosis treatment: A practical review , Ann Clin Transl Neurol, 11(4): 2024,842-855
Gandelman S, Lenzi KA, Markowitz C, Berger JR. A Proposed Approach to Screening and Surveillance Labs for Patients With Multiple Sclerosis on Anti-CD20 Therapy , Neurol Clin Pract, 14(1): 2024
Clark KA, O'Donnell CM, Elliott MA, Tauhid S, Dewey BE, Chu R, Khalil S, Nair G, Sati P, DuVal A, Pellegrini N, Bar-Or A, Markowitz C, Schindler MK, Zurawski J, Calabresi PA, Reich DS, Bakshi R, Shinohara RT; NAIMS Cooperative. Intersite brain MRI volumetric biases persist even in a harmonized multisubject study of multiple sclerosis , J Neuroimaging, 33(6): 2023,941–952
Thebault S, Gandelman S, Lane C, Kim EJ, Pileggi C, Zuroff L, Yamashita LD, Schindler MK, Chiu C, Wilson MR, Berger JR, Markowitz C, Bar-Or A, Fuller R, Brandstadter R, Pruitt AA, Jacobs DA. Severe Neuroinvasive West Nile Virus in Association With Anti-CD20 Monotherapy for Multiple Sclerosis , Neurol Neuroimmunol Neuroinflamm, 10: 2023,e200154