Penn Medicine Provider
Hematology
Charles S. Abrams, MD
4.8
(73)
Accepting new patients
Sees patients age 18 and up
Penn Blood Disorders Center

About me

  • Vice-Chair for Research and Chief Scientific Officer, Department of Medicine
  • Director, PENN-CHOP Blood Center for Patient Care & Discovery
  • Francis C. Wood Professor

Education and training

  • Medical School: Yale University
  • Residency: Temple University Hospital
  • Residency: Hospital of the University of Pennsylvania
  • Fellowship: Hospital of the University of Pennsylvania

What my patients think about me

Average Rating
4.8

73 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

May 2025
5.0
5.0
great person.
May 2025
5.0
5.0
Extremely competent
April 2025
5.0
5.0
he is smart, attentive, communicates well, and has a great manner.
March 2025
5.0
5.0
dr. abrams is an outstanding physician and it is a privilege to be under his care for my condition.

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Abrams is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Wang, Y., Chen, X., Lian, L., Bach, T.L., Golden, J., Morrisey, E.M., Abrams, C.S. PIP5Kγ is required for cardiovascular and neuronal development , Proceedings of the National Academy of Science (U.S.A.), 104(28): 2007,11748-53


Trivedi, C.M., Luo, Y., Yin, Z., Zhang, M., Floss, T., Goettlicher, M., Ruiz, P., Wurst, W., Ferrari, V., Abrams, C.S., Gruber, P., Epstein, J.A. HDAC2 regulates the cardiac hypertrophic response by modulating GSK3β activity , Nature Medicine, 13: 2007,324-331


Wang, Y., Chen, X., Lian, L., Tang, T., Stalker, T.J., Sasaki, T., Brass, L.F., Choi, J.K., Hartwig, J.H., Abrams, C.S. Loss of PIP5KIβ demonstrates that rapid PIP2 synthesis is required for IP3 formation , Proceedings of the National Academy of Science (U.S.A.), 105: 2008,14064-14069


Pan, W., Choi, S.-C., Wang, H., Qin, Y., Volpicelli-Daley, L., Swan, L., Lucast, L., Khooo, C., Zhang, X., Li, L., Abrams, C.S., Sokol, S.Y., Wu, D. Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation , Science, 321: 2008,1350-1353


Wang, Y., Litvinov, R.I., Chen, X., Lian, L., Bach, T.L., Petrich, B., Monkley, S., Critchley, D., Birnbaum, M.J., Weisel, J.W., Hartwig, J.H., Abrams, C.S. Loss of PIP5Kγ, but not PIP5Kβ, impairs the integrity of the membrane cytoskeleton , J. Clinical Investigation, 118(2): 2008,812-819


Mao, Y.S., Yamaga, M., Zhu, X., Wei, M., Sun, H.-Q., Wang, J., Yun, M., Wang, Y., Di Paolo, G., Bennett, M., Mellman, I.S., Abrams, C.S., De Camilli, P.V., Lu, C.Y., and Yin, H.L. Essential and unique roles of PIP5Kγ and α in Fcγ receptor-mediated phagocytosis J. Cell Biology , Journal of Cell Biology, 184: 2009,281-296


Lian, L., Wang, W., Flick, M., Choi, J., Scott, E., Degen, J., Lemmon, M.A., Abrams, C.S. Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis , Blood, In press: 2009


Min, S.H., Abrams, C.S. Why do phosphatidylinositol kinases have so many isoforms? , Biochemical J, 423(1): 2009,99-108


Volpicelli-Daley, L.A., Lucast, L., Gong, L.-W., Liu, L., Sasaki, J., Sasaki, T., Abrams, C.S., Kanaho, Y., De Camilli, P. Phosphatidylinositol 4-phosphate 5-kinases (PIPKIs) and phosphatidylinositol 4,5 bisphosphate [PI(4,5)P2] synthesis in the brain. , J. Biologic Chemistry: 2010,28708-14


Mitsios, J.V., Prévost, N., Kasirer-Friede, A., Gutierrez, E., Groisman, A., Abrams, C.S., Litvinov, R.I., Zemljic-Harpf, A., Ross, R.S., Shattil, S., J. What is vinculin needed for in platelets? , J. Thrombosis & Haemostasis: 2010,2294-2304


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