Casey Jo Humbyrd, MD, MBE

Orthopaedic Surgery
Accepting new patients
Sees patients age 11 to 79
Penn Orthopaedics Pennsylvania Hospital - Farm Journal Building
View 2 additional locations
Schedule onlineCall 215-829-3668
Headshot of Casey Jo Humbyrd, MD, MBE
Penn Medicine Provider

About me

  • Chief, Foot and Ankle Division
  • Director, Program in Surgical Ethics and Health Policy
  • Vice Chair of Quality and Safety
  • Associate Professor of Orthopaedic Surgery at the Pennsylvania Hospital
  • Associate Professor of Orthopaedic Surgery in Medical Ethics and Health Policy

Dr. Humbyrd specializes in the treatment of post-traumatic arthritis and complex sports injuries of the foot and ankle, as well as foot and ankle deformities and arthritis. She has extensive surgical experience in complex reconstructions, including ankle replacement. She was recognized in the 2025 Mainline Region Top Doctors in Orthopedics: Foot & Ankle surgery.

Penn Foot and Ankle Orthopaedic surgeons and Advanced Practice Providers (APPs) work together to provide comprehensive, patient-centered care. Please note that patients may see an APP before an appointment with me.

 

My education and training

  • Medical School: Mount Sinai Medical Center
  • Residency: Johns Hopkins Hospital
  • Fellowship: Mercy Medical Center - Maryland

Watch video featuring Casey Jo Humbyrd, MD, MBE on YouTube

Spoken languages

English
English

Reviews

Average Rating

1456 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
May 2026
ive been going through my issue for over a year before i became her patient and finally i am feeling some relief and she is trying to get me back to where i was prior to my issues
Anonymous
April 2026
high level of professionalism, answering questions, and explaining next steps!
Anonymous
April 2026
the doctor is personable, sympathetic, direct and clear in her explanations.
Anonymous
April 2026
i also had multiple people recommend her

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Humbyrd is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

Research

Publications

Humbyrd CJ. Medical Ethics. , AAOS Comprehensive Orthopedic Review, Fourth Edition: 2024

Humbyrd CJ, Taitsman L. Shared Decision-Making in Limb Threatening Trauma. , Orthopaedic Trauma Association Online Textbook, 56(1): 2024,67-74

Jain D, Hsu M, Forsberg J, Humbyrd CJ. Military Patient Perspectives on Limb Reconstruction Versus Amputation for Lower Extremity Trauma. , American Medical Association Medical Student Research Day. National Harbor DC: 2023

Mauch J, Humbyrd CJ, Lin I, Verchler J. Current Ethics of Hand Transplants in Immunocompetent Children. , Plastic Surgery. Austin, TX. : 2023

Zhuang T, Vandal N, Alqazzaz A, Dehghani B, Humbyrd CJ. Utilization of MRI for Ankle Sprains by Insurance Type. , Eastern Orthopaedic Association Annual Meeting. Charleston, SC.: 2023

Humbyrd CJ. Gray Matters—Virtue Ethics in a Value-driven World: Pareto Meets PROMIS. , Clinical Orthopaedics and Related Research, 481(10): 2023,1886-1887

Xu AL, Humbyrd CJ. Strategies for Reducing Opioid Use in Foot and Ankle Surgery. , Orthopaedic Clinics of North America, 54(4): 2023,485-494

Interviewed by Chelsea Cooman Ep 148: Repairing the Achilles tendon, with Dr. Casey Humbyrd , Podcast of the Journal of Orthopaedic and Sports Physical Therapy (JOSPT Insights).: 2023

Nalatwad A, Quint E, Fazal M, Thompson V, Chen X, Shrestha P, Van Pilsum Rasmussen S, Li Y, Segev D, Humbyrd C, McAdams-DeMarco M. Patient Perspectives on the Use of Aging Metrics for Kidney Transplant Decision-Making. , Progress in Transplantation., 34(3): 2024,81-88

Kwon MP, Hullfish TJ, Boakye LAT, Humbyrd CJ, Baxter JR. Wearable sensor and machine learning estimate tendon load and walking speed during immobilizing boot ambulation. , Scientific Reports, 13(1): 2023,18086