Brian Litt, MD
Neurology
Sees patients age 16 and up
Penn Neuroscience Center - Neurology
Penn Medicine Provider

About me

  • Perelman Professor of Neurology
  • Professor of Neurology in Neurosurgery

Education and training

  • Medical School: Johns Hopkins University School of Medicine
  • Residency: Johns Hopkins Hospital
  • Fellowship: Johns Hopkins Hospital

What my patients think about me

Average Rating

62 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

September 2025
can't get better than dr. litt
September 2025
he is excellent i have had him for quite a few years
September 2025
dr. litt is thorough and compassionate and understanding
September 2025
he has been my doctor since 1990.... great doctor.

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Litt is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Galer PD, McKee JL, Ruggiero SM, Kaufman MC, Ojemann WKS, McSalley I, Ganesan S, Gonzalez AK, Cao Q, Litt B, Helbig I, Conrad EC. Quantitative EEG Biomarkers in the Genetic Epilepsies and Associations With Neurologic Outcomes , Neurology, 105: 2025,e214148


Vizcarra JA, Hefter K, Lafontant DE, Duong MT, Ertefaie A, Litt B, Bassett DS, Siderowf A; Parkinson’s Progression Markers Initiative. Fall Frequency, Risk Factors, and Outcomes in Parkinson's Disease: A Cross-Sectional Analysis , medRxiv: 2025


Sheybani L, Vivekananda U, Sinha N, Conrad E, Litt B, Burgess N, Bush D, Walker MC. Dynamic Interplay Between Wake Slow Waves and Epileptiform Discharges in the Epileptogenic Zone , Neurology, 105: 2025,e214001


Ojemann WKS, Armstrong C, Pattnaik A, Petillo N, Josyula M, Daum A, Zhou DJ, LaRocque J, Korzun J, Kulick-Soper CV, Cornblath EJ, Damaraju S, Shinohara RT, Marsh ED, Davis KA, Litt B, Conrad EC. Can electrical stimulation replace spontaneous seizures in epilepsy surgery? , medRxiv: 2025


Ghosn NJ, Walsh K, Xie K, Aguila C, Pattnaik A, Ma D, Krieger A, Conrad E, Litt B. Inter-ictal spike rates are not modulated by anti-seizure medication taper in the epilepsy monitoring unit: a tale of two confounders , J Neural Eng: 2025


Xie K, Korzun J, Zhou DJ, Chang E, Ghosn NJ, Lavelle S, Oganisian A, Acton EK, Gelfand MA, Roth D, Litt B, Ellis CA. Comparative effectiveness of anti-seizure medications in emulated trials using medical informatics , Brain: 2025


Xu Z, Scheid BH, Conrad EC, Davis KA, Ganguly T, Gelfand MA, Gugger JJ, Jiang X, LaRocque JJ, Ojemann WKS, Sinha SR, Waldman GJ, Wagenaar J, Sinha N, Litt B. Annotating neurophysiologic data at scale with optimized human input , J Neural Eng, 22: 2025,046003


Lamberta LK, Asmar M, Fredwall MM, Ahrens SM, Bai S, Eisner M, Lado FA, Schuele SU, Clarke DF, Abdelmoity AT, Davis KA, Hopp JL, Koubeissi MZ, Bensalem Owen MK, Herman ST, Ostendorf AP; NAEC Center Director Study Group. Status Epilepticus Protocol Variation Across Accredited National Association of Epilepsy Centers Members , Neurology, 104: 2025,e213689


Ojemann WKS, Xie K, Liu K, Chang E, Roth D, Litt B, Ellis CA. Zero-Shot Extraction of Seizure Outcomes from Clinical Notes Using Generative Pretrained Transformers , J Healthc Inform Res, 9: 2025,380-400


Aguila CA, Lucas A, Lavelle S, Pattnaik AR, Kim J, Ojemann WKS, Ma D, Josyula M, Petillo N, LaRocque JJ, Sinha SR, Ellis CA, Parashos A, Gleichgerrcht E, Davis KA, Litt B, Conrad EC. Mesial-to-lateral gradients of epileptiform activity to localize mesial temporal lobe epilepsy , Epilepsia: 2025


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