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Brett Cucchiara, MD

Brett Cucchiara, MD Physician

Director, Neurovascular Lab Associate Professor of Neurology at the Hospital of the University of Pennsylvania

Dr. Cucchiara is employed by Penn Medicine.

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About Dr. Brett Cucchiara

Recognized by America's Top Doctors 2015 – 2017

Recognized by Best Doctors in America 2005 - 2012, 2015 - 2018


Recognized in Philadelphia magazine's May 2018 Top Docs issue


Clinical Specialties


  • Neurology

Programs & Centers:

Board Certification:

  • Neurology, 2001
  • Vascular Neurology, 2006

Clinical Expertise:

  • Cerebrovascular Disease

Description of Clinical Expertise

Cerebrovascular disease. Stroke. TIA. Intracerebral hemorrhage. Carotid stenosis. Arterial dissection. Transcranial Doppler.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Tulane University School of Medicine
Residency: Charity Hospital
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American Academy of Neurology, National American Heart Association / American Stroke Association, National

Hospital Affiliation

Dr. Cucchiara is employed by Penn Medicine.

Hospital Privileges:

  • Chester County Hospital: Has privileges to treat patients in the hospital.
  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Current research involves studying 1) blood biomarkers in patients with transient ischemic attack (TIA), stroke, and other types of cerebrovascular disease, 2) alterations in vascular structure and function in patients with migraine, and 3) use of transcranial Doppler emboli detection for assessment of patients with cerebrovascular disease.

Selected Publications:

Cucchiara B, Datta, R, Aguirre G, Idoko K, Detre J.: Measurement of visual sensitivity in migraine – validation of two scales and correlation with visual cortex activation Cephalalgia 35 (7): 585-92,2015.

Cucchiara B, Wolf RL, Nagae L, Zhang Q, Kasner S, Datta R, Aguirre GK, Detre JA.: Migraine with aura is associated with an incomplete circle of willis: results of a prospective observational study. PLoS ONE 8 : e71007,2013.

Datta R, Aguirre GK, Hu S, Detre JA, Cucchiara B.: Interictal cortical hyperresponsiveness in migraine is directly related to the presence of aura. Cephalalgia 33 (6): 365-74,2013.

Merwick A, Albers GW, Arsava EM, Ay H, Calvet D, Coutts SB, Cucchiara BL, Demchuk AM, Giles MF, Mas JL, Olivot JM, Purroy F, Rothwell PM, Saver JL, Sharma VK, Tsivgoulis G, Kelly PJ.: Reduction in early stroke risk in carotid stenosis with transient ischemic attack associated with statin treatment. Stroke. 44 : 2814-2820,2013.

Ishida K, Raser-Schramm JM, Wilson CA, Kasner SE, Mullen MT, Messe SR, Cucchiara B.: Convergent validity and interrater reliability of estimating the ABCD2 score from medical records. Stroke 44 (3): 803-5,2013.

Raser J, Cucchiara B.: Modifications of the ABCD2 score do not improve risk stratification of TIA patients. Journal of stroke and cerebrovascular diseases. 21 (6): 467-70,2012.

Datta R, Detre JA, Aguirre GK, Cucchiara B.: Absence of changes in cortical thickness in patients with migraine. Cephalalgia. 31 (14): 1452-8,2011.

Raser JM, Mullen MT, Kasner SE, Cucchiara BL, Messe SR.: Cervical carotid artery dissection is associated with styloid process length. Neurology. 77 (23): 2061-66,2011.

Cucchiara BL, Messe SR, Sansing L, MacKenzie L, Taylor RA, Pacelli J, Shah Q, Kasner SE: Lipoprotein-associated phospholipase A2 and C-reactive protein for risk-stratification of patients with TIA. Stroke 40 (7): 2332-6,2009.

Cucchiara, BL, Kasner, SE, Tanne, D, Levine, SR, Demchuk, AM, Messe, S, Sansing, LH, Lyden, P: Factors Associated With Post-Thrombolysis Intracerebral Hemorrhage-Pooled Analysis Of The SAINT-I And SAINT-II Trials. Stroke 40 (4): E121,2009.

View all publications

Academic Contact Info

Department of Neurology
Hospital of the University of Pennsylvania
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 662-6738
Patient appointments: 800-789-7366 (PENN)

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