Brenda B. Hoffman, MD

Renal Electrolyte and Hypertension
Accepting new patients
Sees patients age 18 and up
Penn Renal Electrolyte and Hypertension University City
Schedule onlineCall 800-789-7366
Headshot of Brenda B. Hoffman, MD
Penn Medicine Provider

About me

  • Medical Director, Acute Dialysis Program
  • Professor of Clinical Medicine (Renal-Electrolyte and Hypertension)

My education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: Graduate Hospital
  • Fellowship: University of Pennsylvania Health System

Spoken languages

English
English

Reviews

Average Rating

313 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
May 2026
great bedside manner. informative spent time to explain
Anonymous
May 2026
she is kind, she listens to your concerns and is willing to make adjustments to treatment. all around a+
Anonymous
May 2026
she was friendly and answered my questions.
Anonymous
April 2026
professional, knowledgeable, and personable.

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Hoffman is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

Research

Publications

Boyle, SM, Jacobs, B, Sayni, FA, Hoffman, B Management of the Dialysis Patient with Sickle Cell Disease , Seminars in Dialysis, 29(1): 2016,62-70

Barbieri J, Seshasai R, Shemash A, Sedrak M, Hoffman B, Alley E Thymic neuroendocrine tumor presenting with the ectopic ACTH syndrome , Journal of Thoracic Oncology, 8(6): 2013,e57-8

Tan A, Hoffman B, Rosas SE Patient perception of risk factors associated with chronic kidney disease morbidity and mortality , Ethnicity and Disease, 20: 2010,106-108

Hoffman BB Peritoneal Dialysis , Current Diagnosis and Treatment in Nephrology and Hypertension, Chapter 51(Section 8): 2009,444-452

Hoffman BB Surgery in the Patient with Kidney Disease , Medical Management of the Surgical Patient 3rd edition, Chapter 18: 2008,605-632

Chen S, Hoffman BB, Jim B, Lee JS, Kopp JB, Ziyadeh FN Tubular cells from TGF-beta 1 knockout mice show decreased fibronectin and blunted hypertrophy in high glucose , Kidney Intl, 65: 2004,1191-1204

Chen S, Lee JS, Hoffman BB, Ziyadeh FN Cultured tubule cells from TGF-beta 1 knockout mice exhibit impaired hypertrophy and fibronectin expression in high glucose , JASN, 14: 2003,128A

Dell M, Hoffman BB, Leonard MB, Ziyadeh FN, Schulman SL Increased urinary transforming growth factor beta-1 (TGF-B1) excretion in children with posterior urethral valves , Urology, 56(2): 2000,311-4

Isono M, Mogyorosi A, Han DC, Hoffman BB, Ziyadeh FN Stimulation of TGF-B type II receptor gene expression in mouse mesangial cells by high glucose and in diabetic kidney , Amer Journal of Physiology, 278: 2000,F830-F838

Ziyadeh FN, Hoffman BB, Han DC, Iglesias-De La Cruz MC, Hong SW, Isono M, Chen S, McGowan TA, Sharma K Long term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal anti transforming growth factor-beta antibody in db/db diabetic mice , PNAS, 97(14): 2000,8015-20