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Anne R. Cappola, MD, ScM

Anne R. Cappola, MD, ScM Physician

Professor of Medicine

Dr. Cappola is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties

Specialty:

  • Endocrinology

Programs & Centers:

Board Certification:

  • Endocrinology, Diabetes, & Metabolism, 1999

Clinical Expertise:

  • Chronic Thyroiditis (Hashimoto's Disease)
  • Graves' Disease
  • Hypercalcemia
  • Hyperparathyroidism
  • Hyperthyroidism (Overactive Thyroid)
  • Hypothyroidism (Underactive Thyroid)
  • Osteoporosis
  • Silent Thyroiditis
  • Thyroid Disorders
  • Toxic Nodular Goiter

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Brigham and Women's Hospital
Fellowship: Massachusetts General Hospital
Fellowship: Johns Hopkins Hospital

Memberships

American Thyroid Association, National Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International Gerontological Society of America, National National Scientific Advisory Council for the American Federation for Aging Research, National Philadelphia Endocrine Society, Local The Endocrine Society, National Thyroid Studies Collaboration Group, International Women in Endocrinology, National Women's Health and Aging Studies, National

Hospital Affiliation

Dr. Cappola is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

Anne Rentoumis Cappola, M.D., Sc.M. is a Professor of Medicine in the Division of Endocrinology, Diabetes, and Metabolism; Director of the CTSA-sponsored Center for Human Phenomic Science; and Director of Clinical Research for the Department of Medicine. She is an Associate Editor for the Journal of the American Medical Association (JAMA).

Dr. Cappola leads an NIH-funded program focusing on the hormonal alterations that occur with aging and the clinical impact of these changes Current projects include studies of the indications for treatment of subclinical thyroid dysfunction in older men and women; the role of androgens in the health of older women; hormonal treatments for the frailty syndrome; and metabolic changes in men and women who sustain a hip fracture.

Selected Publications:

Wildisen L, Moutzouri E, Beglinger S, Syrogiannouli L, Cappola AR, Åsvold BO, Bakker SJL, Ceresini G, Dullaart R, Ferrucci L, Grabe H, Jukema JW, Nauck M, Trompet S, Völzke H, Westendorp RGJ, Gussekloo J, Peeters RP, Klöppel S, Aujesky D, Bauer DC, Rodondi N, Del Giovane C, Feller M; Thyroid Studies Collaboration: Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies BMJ Open 9 (7): e029716,2019.

Meuwese CL, van Diepen M, Cappola AR, Sarnak MJ, Shlipak MG, Bauer DC, Fried LP, Iacoviello M, Vaes B, Degryse J, Khaw KT, Luben RN, Asvold BO, Bjoro T, Vatten LJ, de Craen AJM, Trompet S, Iervasi G, Molinaro S, Cersini G, Ferrucci L, Dullaart RPF, Bakker SJL, Jukema JW, Kearney PM, Stott DJ, Peeters RP, Franco OH, VOlzke H, Walsh JP, Bremner A, Sgarbi JA, Maciel RMB, Imaizumi M, Ohishi W, Dekker FW, Rodondi N, Gussekloo J, den Elzen WPJ for the Thyroid Studies Collaboration: Low thyroid function is not associated with an accelerated deterioration in renal function Nephrol Dial Transplant 34 (4): 650-659,2019.

Ellervik C, Roselli C, Christophersen IE, Alonso A, Pietzner M, Sitlani CM, Trompet S, Arking DE, Geelhoed B, Guo X, Kleber ME, Lin HJ, Lin H, Macfarlane P, Selvin E, Shaffer C, Smith AV, Verweij N, Weiss S, Cappola AR, Dörr M, Gudnason V, Heckbert S, Mooijaart S, Marz W, Psaty BM, Ridker PM, Roden D, Stott DJ, Völzke H, Benjamin EJ, Delgado G, Ellinor P, Homuth G, Köttgen A, Jukema JW, Lubitz SA, Mora S, Rienstra M, Rotter JI, Shoemaker MB, Sotoodehnia N, Taylor KD, van der Harst P, Albert CM, Chasman DI: Assessment of the relationship between genetic determinants of thyroid function and atrial fibrillation: a Mendelian randomization study JAMA Cardiol 4 (2): 144-152,2019.

Sanders JL, Arnold AM, Boudreau RM, Hirsch CH, Kizer JR, Kaplan RC, Cappola AR, Cushman M, Jacob ME, Kritchevsky SB, Newman AB: Association of biomarker and physiologic indices with mortality in older adults: Cardiovascular Health Study J Gerontol Med Sci 74 (1): 114-120,2019.

Varadhan R, Russ DW, Gabr RE, Huang J, Kalyani R, Xue QL, Cappola AR, Bandeen-Roche K, Fried LP: Relationship of physical frailty to phosphocreatine recovery in muscle after mild exercise stress in the oldest-old women J Frailty Aging : 2019.

Kannan L, Shaw PA, Morley MP, Brandimarto J, Fang JC, Sweitzer NK, Cappola TP, Cappola AR: Thyroid dysfunction in heart failure and cardiovascular outcomes Circ Heart Fail 11 (12): e005266,2018.

Mulheren RW, Humbert IA, Cappola AR, Fried LP, González-Fernández M: Taste perception and swallow screen results in old-old women Geriatrics 3 (4): ii:E83,2018.

Wopereis DM, Du Puy RS, van Heemst D, Walsh JP, Bremner A, Bakker SJL, Bauer DC, Cappola AR, Ceresini G, Degryse J, Dullaart RPF, Feller M, Ferrucci L, Floriani C, Franker OH, Iacoviello M, Iervasi G, Imaizumi M, Jukema JW, Khaw KT, Luben RN, Molinaro S, Nauck M, Patel KV, Peeters RP, Psaty BM, Razvi S, Schindhelm RK, van Schoor NM, Stott DG, Vaes B, Vanderpump MPJ, Volzke H, Westendorp RGJ, Rodondi N, Cobbaert CM, Gussekloo J, den Elzen WPJ for the Thyroid Studies Collaboration: The relation between thyroid function and anemia: a pooled analysis of individual participant data J Clin Endocrinol Metab 103 (10): 3658-3667,2018.

Teumer A, Chaker L, Groeneweg S, Li Y, Di Munno C, Barbieri C, Schultheiss UT, Traglia M, Ahluwalia TS, Akiyama M, Appel EV, Arking DE, Arnold A, Astrup A, Beekman M, Beilby JP, Bekaert S, Boerwinkle E, Brown SJ, De Buyzere M, Campbell JP, Ceresini G, Cerqueira C, Cucca F, Deary IJ, Deelen J, Eckardt KU, Ekici AB, Eriksson J, Ferrucci L, Fiers T, Fiorillo E, Ford I, Fox CS, Fuchsberger C, Galesloot TE, Gieger C, Gögele M, De Grandi A, Grarup N, Greiser KH, Haljas K, Hansen T, Harris SE, van Heemst D, Hui J: Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation Nat Commun 9 (1): 4455,2018.

Peterson SJ, Cappola AR, Castro MR, Dayan CM, Farwell AP, Hennessey JV, Kopp PA, Ross DS, Samuels MH, Sawka AM, Taylor PN, Jonklaas J, Bianco AC: An online survey of hypothyroid patients demonstrates prominent dissatisfaction Thyroid 28 (6): 707-721,2018.

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Academic Contact Info

Division of Endocrinology, Diabetes, and Metabolism
Room 12-136
Smilow Center for Translational Research, 12th floor
3400 Civic Center Blvd., Building 421

Philadelphia, PA 19104-5160
Phone: (215) 746-6391
Patient appointments: 800-789-7366 (PENN)

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