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Anne R. Cappola, MD, ScM

Anne R. Cappola, MD, ScM Physician

Professor of Medicine

Dr. Cappola is a Penn Medicine employed physician.

Clinical Specialties

Specialty:

  • Medicine
    • Diabetes, Endocrinology and Metabolism

Programs & Centers:

Board Certification:

  • Endocrinology, Diabetes, & Metabolism, 1999

Practice Locations and Appointments

  • Penn Endocrinology

    Perelman Center for Advanced Medicine West Pavilion, 4th Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Brigham and Women's Hospital
Fellowship: Massachusetts General Hospital
Fellowship: Johns Hopkins Hospital

Memberships

American Board of Internal Medicine, National American Federation for Medical Research, National American Thyroid Association, National Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International National Institutes of Health Special Emphasis Panel ZAG1 ZIJ-9 C1, National National Scientific Advisory Council for the American Federation for Aging Research, National Philadelphia Endocrine Society, Local The Endocrine Society, National Thyroid Studies Collaboration Group, International Women in Endocrinology, National Women's Health and Aging Studies, National

Hospital Affiliation

Dr. Cappola is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

Anne Rentoumis Cappola, M.D., Sc.M. is an Associate Professor of Medicine in the Division of Endocrinology, Diabetes, and Metabolism, Associate Scholar in the Center for Clinical Epidemiology (CCEB), Core Faculty Member of the Master's in Translational Research program, and a Fellow in the Institute on Aging. She is an Associate Editor for the Journal of the American Medical Association (JAMA).

Dr. Cappola's research focuses on the hormonal alterations that occur with aging and the clinical impact of these changes. She is funded by the National Institute on Aging. Current projects include studies of the indications for treatment of subclinical thyroid dysfunction in older men and women; the role of androgens in the health of older women; hormonal treatments for the frailty syndrome; and metabolic changes in men and women who sustain a hip fracture.

Selected Publications:

Maggio M, de Vita F, Lauretani F, Bandinelli S, Semba RD, Bartali B, Cherubini A, Cappola AR, Ceda GP, Ferrucci L: Relationship between carotenoids, retinol, and estradiol levels in older women Nutrients 7 (8): 6506-19,2015.

Åsvold BO, Vatten LJ, Bjøro T, Bauer DC, Bremner A, Cappola AR, Ceresini G, den Elzen WPJ, Ferrucci L, Franco OH, Franklyn JA, Gussekloo J, Iervasi G Imaizumi M, Kearney PM, Khaw KT, Newman AB, Peeters RP, Psaty BM, Razvi S, Sgarbi JA, Stott DK, Trompet S, Vanderpump MP, Völzke H, Walsh JP, Westendorp RG, Rodondi N, for the Thyroid Studies Collaboration: Thyroid function within the normal range and risk of coronary heart disease JAMA-Internal Medicine 175 (6): 1037-47,2015.

Chaker L, Baumgartner C, den Elzen W, Ikram, MA, Blum MR, Collet TH, Bakker SJ, Dehgha A, Drechsler C, Luben RN, Hofman A, Portegies ML, Medici M, Iervasi G, Stott DJ, Ford I, Bremner A, Wanner C, Ferrucci L, Newman A, Dullaart RP, Sgarbi JA, Ceresini G, Maciel RM, Westendorp R, Jukema JW, Imaizumi M, Franklyn JA, Bauer DC, Walsh JP, Rasvi S, Khaw KT, Cappola AR, Völzke H, Franco OH, Gussekloo J, Rodondi N, Peeters RP: Subclinical hypothyroidism and the risk of stroke events and fatal stroke: an individual participant data analysis J Clin Endocrinol Metab 100 (6): 2181-91,2015.

Blum MR, Bauer DC, Collet TH, Fink HA, Cappola AR, da Costa BR, Wirth CD, Peeters RP, Åsvold BO, den Elzen WP, Luben RN, Imaizumi M, Bremner AP, Gogakos A, Eastell R, Kearney PM, Strotmeyer ES, Wallace ER, Hoff M, Ceresini G, Rivadeneira F, Uitterlinden AG, Stott DJ, Westendorp RG, Khaw KT, Langhammer A, Ferrucci L, Gussekloo J, Williams GR, Walsh JP, Jüni P, Aujesky D, Rodondi N for the Thyroid Studies Collaboration: Subclinical thyroid dysfunction and fracture risk: a meta-analysis JAMA 313 (20): 2055-65,2015.

Cappola AR, Arnold AM, Wulczyn K, Carlson M, Robbins J, Psaty BM: Thyroid function in the euthyroid range and adverse outcomes in older adults J Clin Endocrinol Metab 100 (3): 1088-96,2015.

Corriere MD, Yao W, Xue QL, Cappola AR, Fried LP, Thorpe RJ, Szanton SL, Kalyani RR: The association of neighborhood characteristics with obesity and metabolic conditions in older women JNHA 18 (9): 792-8,2014.

Maggio M, Snyder PJ, De Vita F, Ceda GP, Milaneschi Y, Lauretani F, Luci M, Cattabiani C, Peachey H, Valenti G, Cappola AR, Longo DL, Ferrucci L: Effects of transdermal testosterone treatment on inflammatory markers in elderly men Endocr Pract 20 (11): 1170-7,2014.

Shores MM, Arnold AM, Biggs ML, Longstregth WT, Smith NL, Kizer JR, Cappola AR, Hirsch CH, Marck BT, Matsumoto AM: Testosterone and dihydrotestosterone and incident ischemic stroke in men in the Cardiovascular Health Study Clin Endocrinol 81 (5): 746-53,2014.

Collet TH, Bauer DC, Cappola AR, Åsvold BO, Weiler S, Vittinghoff E, Gussekloo J, Bremner A, den Elzen WP, Maciel RMB, Vanderpump MP, Cornuz J, Dörr M, Wallaschofski H, Newman AB, Sgarbi JA, Razvi S, Völzke H, Walsh JP, Aujesky D, Rodondi N, for the Thyroid Studies Collaboration: Thyroid antibody status, subclinical hypothyroidism and the risk of coronary heart disease - An individual participant data analysis J Clin Endocrinol Metab 99 (9): 3353-62,2014.

Garin MC, Arnold AM, Lee JS, Robbins J, Cappola AR: Subclinical thyroid dysfunction and hip fracture and bone mineral density in older adults: the Cardiovascular Health Study J Clin Endocrinol Metab 99 (8): 2657-64,2014.

View all publications

Academic Contact Info

Division of Endocrinology, Diabetes, and Metabolism
Room 12-136
Smilow Center for Translational Research, 12th floor
3400 Civic Center Blvd., Building 421

Philadelphia, PA 19104-5160
Phone: (215) 573-5359
Fax: (215) 898-5408
Patient appointments: 800-789-PENN (7366)

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