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Anil Vachani, MD

Anil Vachani, MD Physician

Director of Clinical Research, Section of Interventional Pulmonary and Thoracic Oncology Associate Professor of Medicine at the Hospital of the University of Pennsylvania and the Veteran's Administration Medical Center

Dr. Vachani is employed by Penn Medicine.

Not accepting new patients

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Clinical Specialties


  • Pulmonary Medicine

Programs & Centers:

Board Certification:

  • Pulmonary Disease, 2003

Clinical Expertise:

  • Asbestosis
  • Bronchoscopy
  • Hilar Adenopathy
  • Lung Cancer Screening
  • Lung Lesion
  • Lung Nodule
  • Lung Tumors
  • Needle Procedure
  • Post-Infectious Cough
  • Tracheal Mass

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of California - San Francisco
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American College of Chest Physicians, National American Thoracic Society, National Diagnosis and Management of Lung Cancer: American College of Chest Physicians Evidence-based Clinical Practice Guidelines, 3rd Edition (LC III), National International Association for the Study of Lung Cancer, International Laennec Society, Local

Hospital Affiliation

Dr. Vachani is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Yarmus L, Akulian J, Wahidi M, Chen A, Steltz JP, Solomon SL, Yu D, Maldonado F, Cardenas-Garcia J, Molena D, Lee H, Vachani A: A Prospective Randomized Comparative Study of Three Guided Bronchoscopic Approaches for Investigating Pulmonary Nodules: The PRECISION-1 Study Chest : 2019 (epub ahead of print).

Bagley SJ, Talento S, Mitra N, Meropol NJ, Cohen RB, Langer CJ, Vachani A: Comparative Effectiveness of Carboplatin-Pemetrexed With vs Without Bevacizumab in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer Journal of the National Comprehensive Cancer Network 15 (5): 469-477,2019.

Kossenkov AV, Qureshi R, Dawany NB, Wickramasinghe J, Liu Q, Majumdar RS, Chang C, Widura S, Kumar T, Horng WH, Konnisto E, Criner G, Tsay JJ, Pass H, Yendamuri S, Vachani A, Bauer T, Nam B, Rom WN, Showe MK, Showe LC: A Gene Expression Classifier from Whole Blood Distinguishes Benign from Malignant Lung Nodules Detected by Low-Dose CT Cancer Research 79 (1): 263-73,2019.

Thompson JC, Fan R, Black T, Yu GH, Savitch SL, Chien A, Yee SS, Sen M, Hwang WT, Katz SI, Feldman M, Vachani A, Carpenter EL.: Measurement and immunophenotyping of pleural fluid EpCAM-positive cells and clusters for the management of non-small cell lung cancer patients. Lung Cancer 127 : 25-33,2019.

Weng L, Guo L, Vachani A, Mesaros C, Blair IA.: Quantification of Serum High Mobility Group Box 1 by Liquid Chromatography/High-Resolution Mass Spectrometry: Implications for Its Role in Immunity, Inflammation, and Cancer Anal Chem 90 (12): 7552-7560,2018.

Silvestri GA, Tanner NT, Kearney P, Vachani A, Massion PP, Porter A, Springmeyer SC, Fang KC, Midthun D, Mazzone PJ; PANOPTIC Trial Team: Assessment of Plasma Proteomics Biomarker's Ability to Distinguish Benign From Malignant Lung Nodules: Results of the PANOPTIC (Pulmonary Nodule Plasma Proteomic Classifier) Trial Chest : 2018.

Morris S, Vachani A, Pass HI, Rom WN, Ryden K, Weiss GJ, Hogarth DK, Runger G, Richards D, Shelton T, Mallery DW: Whole blood FPR1 mRNA expression predicts both non-small cell and small cell lung cancer Int J Cancer : 2018.

Huang J., Liu Y., Vitale S., Penning T.M., Whitehead A.S., Blair I.A., Vachani A., Clapper M., Muscat J.E., Lazarus P., Scheet P., Moore J.H., Chen Y.: On meta- and mega-analyses for gene–environment interactions Genetic Epidemiology : 2017.

Aggarwal C, Wang X, Ranganathan A, Torigian D, Troxel A, Evans T, Cohen RB, Vaidya B, Rao C, Connelly M, Vachani A, Langer C, Albelda S: Circulating tumor cells as a predictive biomarker in patients with small cell lung cancer undergoing chemotherapy Lung Cancer 112 : 118-125,2017.

Tanner NT, Porter A, Gould MK, Li XJ, Vachani A, Silvestri GA: Physician Assessment of Pretest Probability of Malignancy and Adherence With Guidelines for Pulmonary Nodule Evaluation. Chest 152 (2): 263-270,2017.

Academic Contact Info

Pulmonary, Allergy, and Critical Care Division
University of Pennsylvania School of Medicine
Suite 216, Stemmler Hall
3450 Hamilton Walk

Philadelphia, PA 19104
Phone: (215) 573-7931
Patient appointments: 800-789-7366 (PENN)

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