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Andrew E. Epstein, MD, FAHA, FACC, FHRS

Andrew E. Epstein, MD, FAHA, FACC, FHRS Physician

Professor of Medicine at the Hospital of the University of Pennsylvania and the Veteran's Administration Medical Center

Dr. Epstein is employed by Penn Medicine.

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About Dr. Andrew E. Epstein

Recognized by America's Top Doctors, 2012 - 2018
Recognized by Best Doctors in America 2011, 2012, 2015 - 2018
Recognized in Philadelphia magazine's annual Top Docs issues for 2018 and 2019

Clinical Specialties


  • Cardiology

Programs & Centers:

Board Certification:

  • Cardiovascular Disease, 1983
  • Internal Medicine, 1980

Clinical Expertise:

  • Atrial Fibrillation (Afib)

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Rochester School of Medicine
Residency: Barnes-Jewish Hospital - Washington University, St. Louis
Fellowship: University of Alabama Hospital


Abbott, International American College of Cardiology, National American College of Physicians, National American Heart Association, Alabama Affiliate, Local American Heart Association, National Association of University Cardiologists, National Cardiac Electrophysiology Society, National National Heart, Lung and Blood Institute, National National Institutes of Health, National North American Society of Pacing and Electrophysiology / Heart Rhythm Society, National

Hospital Affiliation

Dr. Epstein is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Defibrillation and cardioversion; devices for the treatment of arrhythmias (implantable cardioverter-defibrillators, pacemakers); Electrophysiology and treatment of atrial and ventricular arrhythmias (interventional electrophysiology/ablation, surgical, pharmacologic); Clinical trials in arrhythmia treatment.

Selected Publications:

Russo AM, Stainback RF, Bailey SR, EPSTEIN AE, Heidenreich PA, Jessup M, Kapa S, Kremers MS, Lindsay BD, Warner Stevenson L.: ACCF/HRS/AHA/ASE/HFSA/SCAI/SCCT/SCMR Appropriate use criteria for implantable cardioverter-defibrillators and cardiac resynchronization therapy. J Am Coll Cardiol 61 : 1318-1368,2013.

EPSTEIN AE, Callans DJ.: Inducible fast VT post STEMI: is VT ever OK? Circulation Arrhy Electrophysiol in press : 2013.

Fogel R, EPSTEIN AE, Estes NAM, Lindsey B, DiMarco J, Kremers M, Kapa S, Brindis R, Russo A.: The ultimate dilemma – the disconnect between the guidelines, the appropriate use criteria and reimbursement coverage decisions. J Am Coll Cardiol 63 : 12-14,2014.

Gheorghiade M, Fonarow GC, van Veldhuisen DJ, Cleland JGF, Butler J, EPSTEIN AE, Patel K, Aban IB, Aronow W, Anker SD, Ahmed A.: Lack of evidence of increased mortality among patients with atrial fibrillation taking digoxin: Findings from post hoc propensity-matched analysis of the AFFIRM trial. Eur Heart J In press : 2013.

Kapa, S, EPSTEIN A, Callans D, Garcia F, Lin D, Bala R, Riley M, Hutchinson M, Gerstenfeld E, Tzou W, Marchlinski F, Frankel D, Cooper J, Supple G, Dixit S.: Assessing arrhythmia burden after catheter ablation of atrial fibrillation using an implantable loop recorder: the ABACUS study. Heart Rhythm 24 : 875-881,2013.

EPSTEIN AE, Abraham WT, Bianco N, Kern KB, Mirro M, Rao SV, Rhee EK, Solomon SD, Szymkiewicz S.: Wearable cardioverter-defibrillator use in patients perceived to be at high risk early post myocardial infarction. J Am Coll Cardiol in press : 2013.

Shariff N, Desai RV, Patel K, Ahmed MI, Fonarow GC, Rich MW, Aban IB, Banach M, Love TE, White M, Aronow WS, EPSTEIN AE, Ahmed A.: Rate-control versus rhythm-control strategies and outcomes in septuagenarian patients with atrial fibrillation. American Journal of Medicine in press : 2013.

EPSTEIN AE.: “Please implant a defibrillator in my patient”: it’s déjà vu all over again. Heart Rhythm 9 : 47-48,2012.

Tomson TT, Kapa S, Bala R, Riley MP, Lin D, EPSTEIN AE, Deo R, Dixit S.: Risk of stroke and atrial fibrillation after radiofrequency catheter ablation of typical atrial flutter. Heart Rhythm 9 : 1779-1784,2012.

Tracy CM, EPSTEIN AE, Darbar D, DiMarco JP, Dunbar SB, Estes NAM 3rd, Ferguson TB, Hammill SC, Karasik PE, Link MS, Marine JE, Schoenfeld MH, Shanker AJ, Silka MJ, Stevenson LW, Stevenson WG, Varosy PD.: 2012 ACCF/AHA/HRS focused update of the 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 60 : 1297-1313,2012.

Estes NAM, Sacco RL, Al-Khatib SM, Ellinor PT, Bezanson J, Alonso A, Antzelevitch C, Brockman R, Chen PS, Chugh S, Curtis AB, DiMarco JP, Ellenbogen KA, EPSTEIN AE, Ezekowitz MD, Fayad P, Gage BF, Go AS, Hlatky MA, Hylek EM, Jerosch-Herold M, Konstam M, Lee R, Packer DL, Po SS, Prystowsky EN, Redline S, Rosenberg Y, Van Wagoner DR, Wood K, Yue L, Benjamin EJ.: American Heart Association Atrial Fibrillation Summit Proceedings. Circulation 124 : 363-372,2011.

EPSTEIN AE, DiMarco JP, Ellenbogen KA, Estes NA, Freedman RA, Gettes LS, Gregoratos G, Gillinov AM, Hammill SC, Hayes DL, Hlatky MA, Newby LK, Page RL, Schoenfeld MH, Silka MJ, Stevenson LW, Sweeney MO.: ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices). J Am Coll Cardiol 51 : e1,2008.

Academic Contact Info

Electrophysiology Section
Cardiovascular Division
University of Pennsylvania
3400 Spruce Street
9 Founders

Philadelphia, PA 19104
Phone: (215) 615-4332
Patient appointments: 800-789-7366 (PENN)

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