Description of Research Expertise:
1.Aldosterone effects on clinical outcomes with varying dietary sodium intake: The goal of this project is to evaluate the role of serum aldosterone and its effects on clinical outcomes of mortality, cardiovascular disease, and kidney disease in individuals with low dietary sodium intake. Several different populations will be used to study this, including healthy individuals and individuals with albuminuria and CKD, both from prior cohort studies.
2. Urine potassium and association with clinical outcomes of mortality, cardiovascular disease, and chronic kidney disease using the MDRD Study database, Primary Investigator. This project is focused on identifying the risk of low potassium intake and adverse clinical outcomes in a CKD population.
3. Tubular injury as an early marker for CKD. This project aims to use urine electrolytes (for calculation of the urine anion gap) as a marker for tubular damage in early CKD, which we hypothesize will be related to progression of CKD. This work is an extension of previous publications that have shown that serum bicarbonate is a marker for progression of kidney disease.
Abramovitz Blaise, Leonberg-Yoo Amanda, Bahrainwala Jehan Z, Litt Harold, Rudnick Michael R: Bilateral Renal Infarctions During the Use of Sumatriptan. Kidney international reports 3 (5): 1233-1236,2018.
Bansal Amar D, Leonberg-Yoo Amanda, Schell Jane O, Scherer Jennifer S, Jones Christopher A: Ten Tips Nephrologists Wish the Palliative Care Team Knew About Caring for Patients with Kidney Disease. Journal of palliative medicine 21 (4): 546-551,2018.
Rudnick MR, Leonberg-Yoo AK: The Death of Contrast-Induced Nephropathy is Premature Kidney News 10 (4): 2018.
AK Leonberg-Yoo, JE Rame, MR Rudnick: Renal Replacement Therapies in Patients with Left Ventricular Assist Devices Ventricular-Assist Devices and Kidney Disease: Clinical Perspectives : 2018.
Leonberg-Yoo AK, Rudnick MR: NephMadness 2018: Contrast Nephropathy is Back! AJKD Blog : 2018.
Leonberg-Yoo Amanda K, Rudnick Michael R: Tobacco Use: A Chronic Kidney Disease Accelerant. American journal of nephrology 46 (4): 257-259,2017.
Bahrainwala Jehan Z, Leonberg-Yoo Amanda K, Rudnick Michael R: Use of Radiocontrast Agents in CKD and ESRD. Seminars in dialysis 30 (4): 290-304,2017.
Leonberg-Yoo Amanda K, Sarnak Mark J: Don't Pass the Salt: Evidence to Support Avoidance of High Salt Intake in CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation 69 (2): 175-178,2016.
Leonberg-Yoo Amanda K, Tighiouart Hocine, Levey Andrew S, Beck Gerald J, Sarnak Mark J: Urine Potassium Excretion, Kidney Failure, and Mortality in CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation 69 (3): 341-349,2016.
AK Leonberg-Yoo, DE Weiner: Epidemiology of End-Stage Renal Disease Core Concepts in Dialysis and Continuous Therapies : 2016.