Description of Research Expertise
Alexander Lin, M.D., is the Morton M. Kligerman, MD Endowed Professor of Radiation Oncology. Dr. Lin leads research programs in personalized approaches in the multidisciplinary treatment of head and neck cancer. Dr. Lin leads studies in novel methods of toxicity mitigation in patients with Human Papillomavirus (HPV)-associated cancers of the oropharynx. He also specializes in clinical trials investigating new radiosensitizing agents targeting the tumor microenvironment to improve disease outcomes, for which he receives funding from the National Cancer Institute (NCI) and National Institutes of Health (NIH).
Dr. Lin completed his undergraduate studies at Yale University and his medical training at the University of Michigan. He is a board-certified radiation oncologist and practicing physician at the University of Pennsylvania, Perelman School of Medicine.
Selected Publications
Patel AM, Haleem A, Choudhry HS, Maxwell R, Lukens JN, Lin A, Brody RM, Brant JA, Carey RM: Choice of Adjuvant Radiotherapy Facility in Major Salivary Gland Cancer Laryngoscope 00 : 1-13,2024.
Sollecito TP, Helgeson ES, Lalla RV, Treister NS, Schmidt BL, Patton LL, Lin A, Brennan MT: Reduced mouth opening in patients with head and neck cancer treated with radiation therapy: an analysis of the Clinical Registry of Dental Outcomes in Head and Neck Cancer Patients (OraRad) Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology : 2023 (Accepted 11/20/2023).
Lu J, Cao A, Shimunov D, Sun L, Lukens J, Lin A, Cohen R, Basu D, Cannady S, Rajasekaran K, Weinstein G, Brody R: Functional Outcomes in Patients with HPV+ Oropharyngeal Squamous Cell Cancer Treated with Trimodality Therapy The Laryngoscope 133 : 3013–3020,2023.
Deng J, Lukens JN, Zhu J, Cohn JC, Andersen LP, Spinelli BA, Quinn RJ, Chittams J, McMenamin E, Lin A: Patient Experience of Photobiomodulation Therapy in Head and Neck Chronic Lymphedema Journal of Palliative Medicine 26 (9): 1225-1233,2023.
Trotter J, Lukens JN, Lin A: Advances in Proton Therapy for the Management of Head and Neck Tumors Surgical Oncology Clinics of North America 32 (3): 587-598,2023.
Lalla RV, Hodges JS, Treister NS, Sollecito TP, Schmidt BL, Patton LL, Lin A, Brennan MT: Tooth-level predictors of tooth loss and exposed bone after radiation therapy for head and neck cancer Journal of the American Dental Association 154 (6): 519-528.e4,2023.
Berlin E, Ma DJ, Bakst RL, Quon H, Lin A, Lukens JN: Close Margins Following Transoral Robotic Surgery (TORS) for HPV+ Oropharyngeal Carcinoma: A review of the literature and practical recommendations Practical Radiation Oncology 13 (3): 251-255,2023.
Patton LL, Helgeson ES, Brennan MT, Treister NS, Sollecito TP, Schmidt BL, Lin A, Cherah BS, Lalla RV: Oral health-related quality of life after radiation therapy for head and neck cancer: the OraRad study
Supportive Care in Cancer 31 (5): 286,2023.
Kim KN, Harton J, Mitra N, Lukens JN, Lin A, Amaniera I, Doucette A, Gabriel P, Baumann B, Metz J, Andrzej Wojcieszynski A: Acute toxicity in patients treated with concurrent chemoradiotherapy with proton versus intensity-modulated radiation therapy for nonmetastatic head and neck cancers Head and Neck 44 (11): 2386-2394,2022 .
Deng J, Lukens JN, Cohn JC, McMenamin E, Murphy B, Spinelli BA, Murphy N, Steimetz AK, Landriau MA, Lin A: Conducting a supportive oncology clinical trial during the COVID-19 pandemic: challenges and strategies Trials 23 (1): 927,2022.
Academic Contact Information
University of Pennsylvania
Department of Radiation Oncology
3400 Civic Center Blvd
TRC 2 West
Philadelphia,
PA
19104
Phone: 215-662-3198
Patient appointments: 800-789-7366