Selected Publications

Kevin L Ma, Cimarron E Sharon, Andrew Kossenkov, Lynn M Schuchter, Ravi K Amaravadi, Tara C Mitchell, John T Miura, Xiaowei Xu, Alexander C Huang, Giorgos C Karakousis: Immune microenvironment in sentinel lymph nodes of high-risk clinical stage IIB/C melanoma Society for Melanoma Research (SMR) Congress, Philadelphia, PA. : 2023.

Guanning Wang1, Daniel Yoon2, Justin Kim1, Aaron Nickie1, Stella Park1, Ajeya Nandi1, Patrick Yan1, Mary Carberry1, Lydia Giles1, Khushboo Patel1, Ravi K. Amaravadi1, Lynn M. Schuchter1, Giorgos C. Karakousis1, Xiaowei Xu1, Tara. C. Mitchell, Alexander C. Huang: Antigen-specific profiling for neoadjuvant anti-PD-1 therapy in melanoma Society for Melanoma Research (SMR Congress), Philadelphia, PA. : 2023.

Sharon CE, Tortorello GN, MA KL, Huang AC, Xu X, Giles LR, McGettigan S, Kreider K, Schuchter LM, Mathew AJ, Amaravadi RK, Gimotty PA, Muira JT, Karakousis GC, Mitchell TC: Long-term outcomes to neoadjuvant pembrolizumab based on pathological response for patients with resectable stage III/IV cutaneus melanoma. Ann Oncol 34 (9): 806-812,2023.

Ou L, Liu S, Wang H, Guo Y, Guan L, Shen L, Luo R, Elder DE, Huang AC, Karakousis G, Muira J, Mitchell T, Schuchter L, Amaravadi R, Flowers A, Mou H, Yi F, Guo W, Ko J, Chen Q, Tian B, Herlyn M, Xu X: Patient-derived melanoma organoid models facilitate the assessment of immunotherapies. EBio Medicine 92 : 104614,2023.

Shah PD, Huang AC, Xu X, Orlowski R, Amaravadi RK, Schuchter LM, Zhang P, Tchou J, Matlawski T, Cervini A, Shea J, Gilmore J, Lledo L, Dengel K, Marshall A, Wherry EJ, Linette GP, Brennan A, Gonzalez V, Kulikovaskaya I, Lacey SF, Plesa G, June CH, Vonderheide RH, Mitchell TC.: Phase 1 trial of autologous RNA-electroporated cMET-directed CAR T cells administered intravenously in patients with melanoma and breast carcinoma. Cancer Res Commun 3 (5): 821-829,2023.

Wang G, Lyudovyk O, Kim JY, Lin YH, Elhanati Y, Mathew D, Wherry EJ, Herati RS, Greenplate AR, Greenbaum B, Vardhana SA, Huang AC.: High-throughput interrogation of immune responses using the Human Immune Profiling Pipeline. STAR Protocol 4 (2): 102289,2023.

Cosgriff CV, Miano TA, Mathew D, Huang AC, Giannini HM, Kuri-Cervantes L, Pampena MB, Ittner CAG, Weisman AR, Agyekum RS, Dunn TG, Oniyide O, Turner AP, D'Andrea K, Adamski S, Greenplate AR, Anderson BJ, Harhay MO, Jones TK, Reilly JP, Mangalmurti NS, Shashaty MGS, Betts MR, Wherry EJ, Meyer NJ: Validating a Proteomic Signature of Severe COVID-19 Crit Care Explor 4 (12): 30800,2022.

Giles JR, Ngiow SF, Manne S, Baxter AE, Khan O, Wang P, Staupe R, Abdel-Hakeem MS, Huang H, Mathew D, Painter MM, Wu JE, Huang YJ, Goel RR, Yan PK, Karakousis GC, Xu X, Mitchell TC, Huang AC, Wherry EJ.: Shared and distinct biological circuits in effector, memory and exhausted CD8(+) T cells revealed by temporal single-cell transcriptomics and epigenetics Nat Immunol 23 (11): 1600-1613. ,2022.

Herati RS, Knorr DA, Vella LA, Silva LV, Chilukuri L, Apostolidis SA, Huang AC, Muselman A, Manne S, Kuthuru O, Staupe RP, Adamski SA, Kannan S, Kurupati RK, Ertl HCJ, Wong JL, Bournazos S, McGettigan S, Schuchter LM, Kotecha RR, Funt SA, Voss MH, Motzer RJ, Lee CH, Bajorin DF, Mitchell TC, Ravetch JV, Wherry EJ.: PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine Nat Immunol 23 (8): 1183-1192.,2022.

Lyudovyk O, Kim JY, Qualls D, Hwee MA, Lin YH, Boutemine SR, Elhanati Y, Solovyov A, Douglas M, Chen E, Babady NE, Ramanathan L, Vedantam P, Bandlamudi C, Gouma S, Wong P, Hensley SE, Greenbaum B, Huang AC, Vardhana SA.: Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses Cancer Cell 40 (7): 738-753,2022.

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