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Albert M. Maguire, MD

Albert M. Maguire, MD Physician

Professor of Ophthalmology at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia

Dr. Maguire is a Penn Medicine employed physician.

About Dr. Albert M. Maguire

Recognized by Best Doctors in America 2003-2004, 2005-2006, 2007-2008, 2009-2010, 2011-2012, 2013-2014

Recognized by Suburban Life magazine's "Top Physicians 2010" issue

Recognized in Philadelphia Magazine's May 2002 Top Docs issue

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties

Specialty:

  • Ophthalmology

Programs & Centers:

Board Certification:

  • Ophthalmology, 1991

Clinical Expertise:

  • Age-related Macular Degeneration (AMG)
  • AIDS-related Eye Disorders
  • Choroidal Tumor
  • Cryosurgery
  • Diabetic Retinopathy
  • Diabetic Retinopathy - Laser
  • Eye Emergencies
  • Eye Floaters
  • Eye Inflammation
  • Eye Orbital Tumor
  • Gene Therapy
  • Genetic Eye Diseases (GED)
  • Macular Degeneration Laser Treatment
  • Macular Degneration
  • Macular Disorders
  • Macular Hole
  • Melanoma
  • Pediatric Ophthalmology
  • Retina Surgery
  • Retinal Degeneration
  • Retinal Detachment
  • Retinal Disorders
  • Retinal Edema
  • Retinal Hole
  • Retinal Infection (Retinitis)
  • Retinal Laser Therapy
  • Retinal Tears
  • Retinal Tumors
  • Retinal Vascular Disease
  • Sickle Cell Retinopathy
  • Uveitis
  • Vision Loss
  • Vitreo Retinal Laser Surgery
  • Vitreous Surgery (Vitrectomy)

Description of Clinical Expertise

diabetic retinopathy, retinopathy of prematurity, macular degeneration, sickle cell disease, gene therapy, retinal degeneration

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Superior Vision Benefit Mgmt, Inc (Block Vision)
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Harvard Medical School
Residency: Yale-New Haven Hospital
Residency: Johns Hopkins Hospital
Fellowship: Beaumont Hospital, Royal Oak

Memberships

American Academy of Ophthalmology, National American Society for Cell and Gene Therapy, National Association for Research in Vision and Ophthalmology, National National Academy of Sciences, National NIH Study Section (National Eye Institute), National Ophthalmic Technology Assessment Committee, American Academy of Ophthalmology, National Ophthalmological Associate, Research to Prevent Blindness, National Phi Beta Kappa Society, National The Macula Society, National The Vitreous Society, National The Wellcome Trust, International

Hospital Affiliation

Dr. Maguire is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

Gene therapy for retinal degeneration, gene therapy for ocular neovascularization, Subretinal surgery

Selected Publications:

Ramachandran Pavitra, Lee Vivian, Wei Zhangyong, Song Ji Yun, Casal Giulia, Cronin Therese, Willett Keirnan, Huckfeldt Rachel, Morgan Jessica I W, Aleman Tomas S, Maguire Albert M, Bennett Jean: Evaluation of dose and safety of AAV7m8 and AAV8BP2 in the non-human primate retina. Human gene therapy : 2016.

Bennett Jean, Wellman Jennifer, Marshall Kathleen A, McCague Sarah, Ashtari Manzar, DiStefano-Pappas Julie, Elci Okan U, Chung Daniel C, Sun Junwei, Wright J Fraser, Cross Dominique R, Aravand Puya, Cyckowski Laura L, Bennicelli Jeannette L, Mingozzi Federico, Auricchio Alberto, Pierce Eric A, Ruggiero Jason, Leroy Bart P, Simonelli Francesca, High Katherine A, Maguire Albert M: Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial. Lancet (London, England) 388 (10045): 661-72,2016.

Bonafede Lucas, Ficicioglu Can H, Serrano Leona, Han Grace, Morgan Jessica I W, Mills Monte D, Forbes Brian J, Davidson Stefanie L, Binenbaum Gil, Kaplan Paige B, Nichols Charles W, Verloo Patrick, Leroy Bart P, Maguire Albert M, Aleman Tomas S: Cobalamin C Deficiency Shows a Rapidly Progressing Maculopathy With Severe Photoreceptor and Ganglion Cell Loss. Investigative ophthalmology & visual science 56 (13): 7875-87,2015.

Ashtari Manzar, Zhang Hui, Cook Philip A, Cyckowski Laura L, Shindler Kenneth S, Marshall Kathleen A, Aravand Puya, Vossough Arastoo, Gee James C, Maguire Albert M, Baker Chris I, Bennett Jean: Plasticity of the human visual system after retinal gene therapy in patients with Leber's congenital amaurosis. Science translational medicine 7 (296): 296ra110,2015.

Morgan Jessica I W, Han Grace, Klinman Eva, Maguire William M, Chung Daniel C, Maguire Albert M, Bennett Jean: High-resolution adaptive optics retinal imaging of cellular structure in choroideremia. Investigative ophthalmology & visual science 55 (10): 6381-97,2014.

Black Aaron, Vasireddy Vidyullatha, Chung Daniel C, Maguire Albert M, Gaddameedi Rajashekhar, Tolmachova Tania, Seabra Miguel, Bennett Jean: Adeno-associated virus 8-mediated gene therapy for choroideremia: preclinical studies in in vitro and in vivo models. The journal of gene medicine 16 (5-6): 122-30,2014.

Vasireddy Vidyullatha, Mills Jason A, Gaddameedi Rajashekhar, Basner-Tschakarjan Etiena, Kohnke Monika, Black Aaron D, Alexandrov Krill, Zhou Shangzhen, Maguire Albert M, Chung Daniel C, Mac Helen, Sullivan Lisa, Gadue Paul, Bennicelli Jeannette L, French Deborah L, Bennett Jean: AAV-mediated gene therapy for choroideremia: preclinical studies in personalized models. PloS one 8 (5): e61396,2013.

Vandenberghe Luk H, Bell Peter, Maguire Albert M, Xiao Ru, Hopkins Tim B, Grant Rebecca, Bennett Jean, Wilson James M: AAV9 targets cone photoreceptors in the nonhuman primate retina. PloS one 8 (1): e53463,2013.

Bennett J, Ashtari M, Wellman J, Marshall KA, Cyckowski LL, Chung DC, McCague S, Pierce EA, Chen Y, Bennicelli JL, Zhu X, Ying GS, Sun J, Wright JF, Auricchio A, Simonelli F, Shindler KS, Mingozzi F, High KA, Maguire AM.: AAV2 Gene Therapy Readministration in Three Adults with Congenital Blindness. Sci Transl Med. 4 (120): 120ra15,2012.

Ashtari M, Cyckowski LL, Monroe JF, Marshall KA, Chung DC, Auricchio A, Simonelli F, Leroy BP, Maguire AM, Shindler K, Bennett J.: The human visual cortex responds to gene therapy–mediated recovery of retinal function J Clin Invest. 121 (6): 2160-8,2011.

Academic Contact Info

Scheie Eye Institute
Department of Ophthalmology
University of Pennsylvania
51 North 39th Street

Philadelphia, PA 19104
Patient appointments: 800-789-PENN (7366)

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