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Adam C. Cuker, MD, MS

Adam C. Cuker, MD, MS Physician

Assistant Director, Hematology/Oncology Fellowship Program Clinical Director, Penn Blood Disorders Center, University of Pennsylvania Director, Penn Comprehensive and Hemophilia Thrombosis Program Associate Professor of Pathology and Laboratory Medicine Associate Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Cuker is employed by Penn Medicine.

About Dr. Adam C. Cuker

Recognized by America's Top Doctors for 2017, 2018, and 2019

Recognized in Philadelphia magazine's annual Top Docs issues for 2018 and 2019

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Hematology

Programs & Centers:

Board Certification:

  • Hematology, 2009

Clinical Expertise:

  • Anticoagulation
  • Antiphospholipid Syndrome
  • Antithrombin Deficiency
  • Autoimmune Hemolytic Anemia
  • Blood Clot
  • Blood Disorders
  • Blood Platelet Disorders
  • Catastrophic Antiphospholipid Syndrome
  • Coagulation Disorders
  • Cold Agglutinin Disease
  • Deep Vein Thrombosis
  • Factor Eight Disorder
  • Factor Nine Deficiency
  • Factor V Leiden
  • Hemolytic Anemia
  • Hemolytic Uremic Syndrome
  • Heparin-Induced Thrombocytopenia
  • Hypercoagulable State
  • Idiopathic Thrombocytopenic Purpura
  • Lupus Anticoagulant
  • Maternal Anticoagulation
  • Maternal Hematologic Disorders
  • Maternal Thrombophilia
  • Paroxysmal Nocturnal Hemoglobinuria
  • Partial Thromboplastin Time Blood Test
  • Petechiae
  • Postthrombotic Syndrome
  • Protein C Deficiency
  • Protein S Deficiency
  • Prothrombin Gene Mutation
  • Purpura
  • Recurrent Thrombosis
  • Thrombocytopenia
  • Thrombophilia
  • Thrombotic Disorders
  • Thrombotic Thrombocytopenic Purpura
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Yale University
Residency: Brigham and Women's Hospital
Fellowship: Hospital of the University of Pennsylvania


American College of Cardiology, National American College of Physicians, National American Heart Association, National American Society of Hematology Clinical Research Training Institute, National American Society of Hematology, National American Thrombosis and Hemostasis Network, National Anticoagulation Forum, National Data Safety and Monitoring Committee, Bridging ITP Study, International Hemostasis and Thrombosis Research Society, National International Society on Thrombosis and Haemostasis, International National Hemophilia Foundation, National

Hospital Affiliation

Dr. Cuker is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Heparin-induced thrombocytopenia, Immune thrombocytopenia, Thrombosis, Anticoagulation, Platelet disorders, Bleeding disorders

Selected Publications:

Cuker A, Rux AH, Hinds JL, Dela Cruz M, Yarovoi SV, Brown IAM, Yang W, Konkle BA, Arepally GM, Watson SP, Cines DB, Sachais BS: Novel diagnostic assays for heparin-induced thrombocytopenia Blood 121 (18): 3727-3732,2013.

Cuker A, Cines DB: Protamine-induced thrombocytopenia? Blood 121 : 2818-2819,2013 .

Siegal D, Cuker A: Reversal of novel oral anticoagulants in patients with major bleeding J Thromb Thrombolysis 35 (3): 391-398,2013 .

Sood S, Cuker A, Wang C, Metjian A, Chiang E, Soucie J, Konkle B: Similarity in Joint Function Limitation in Type 3 Von Willebrand Disease and Moderate Haemophilia A Haemophilia 19 (4): 595-601,2013 .

Tanhehco YC, Cuker A, Rudnick M, Sachais BS: Investigation of a potential protective mechanism against heparin-induced thrombocytopenia in patients on chronic intermittent hemodialysis Thromb Res 131 (3): 244-248,2013 .

Cuker A, Gimotty PA, Crowther MA, Warkentin TE: Predictive value of the 4Ts scoring system for heparin-induced thromboctopenia: a systematic review and meta-analysis Blood 120 (20): 4160-4167,2012 .

Sachais BS, Litvinov RI, Yarovoi SV, Rauova L, Hinds JL, Rux AH, Arepally GM, Poncz M, Cuker A, Weisel JW, Cines DB: Dynamic antibody binding properties in the pathogenesis of HIT Blood 120 (5): 1137-1142,2012.

Martinez M, Cuker A, Mills A, Lightfoot R, Fan Y, Tang W, Hazen SL, Ischiropoulos H: Nitrated fibrinogen is a biomarker of oxidative stress in venous thromboembolism Free Radic Biol Med 53 (2): 230-236,2012.

Cuker A, Cines DB: How I treat heparin-induced thrombocytopenia Blood 119 (10): 2209-2218,2012 .

Lakshmanan S, Cuker A: Comtemporary management of primary immune thrombocytopenia (ITP) in adults J Thromb Haemost 10 (10): 1988-1998,2012 .

Academic Contact Info

Penn Comprehensive Hemophilia and Thrombosis Program
HUP, 3 Dulles
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 615-8012
Patient appointments: 800-789-7366 (PENN)

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