Description of Research Expertise:
Cancer immunotherapy
Vaccines
Cellular therapy
Phase I trials
CAR T cells
Selected Publications:
Adam D. Cohen*, Nikoletta Lendvai*, Sarah Nataraj, Naoko Imai, Achim A. Jungbluth, Ioanna Tsakos, Adeeb Rahman, Anna Huo-Chang Mei, Herman Singh, Katarzyna Zarychta, Seunghee Kim-Schulze, Andrew Park, Ralph Venhaus, Katherine Alpaugh, Sacha Gnjatic, and Hearn J. Cho: Autologous lymphocyte infusion supports tumor antigen vaccine-induced
immunity in autologous stem cell transplant for multiple myeloma Cancer Immunology Research : 2019.
Luca Bernabei, Alfred L. Garfall, J. Joseph Melenhorst, Simon F Lacey, Edward A. Stadtmauer, Dan T. Vogl, Vanessa Gonzalez, Gabriela Plesa, Regina M Young, Adam Waxman, Bruce L Levine, Carl H June, Michael C. Milone, and Adam D. Cohen: PD-1 Inhibitor Combinations As Salvage Therapy for Relapsed/Refractory Multiple Myeloma (MM) Patients Progressing after BCMA-Directed CAR T Cells Blood, ASH Annual Meeting, San Diego, CA 132 : #1973,2018.
Tara Gregory, Adam D. Cohen, Caitlin L. Costello, Syed Abbas Ali, Jesus G. Berdeja, Eric M Ostertag, Christopher Martin, Devon J Shedlock, Michelle Lynn Resler, Matthew A. Spear, Robert Z. Orlowski, and Krina K. Patel: Efficacy and Safety of P-Bcma-101 CAR-T Cells in Patients with Relapsed/Refractory (r/r) Multiple Myeloma (MM) Blood, ASH Annual Meeting, San Diego, CA 132 : #1012,2018.
Adam D. Cohen, J. Joseph Melenhorst, Alfred L. Garfall, Simon F Lacey, Megan Davis, Dan T. Vogl, Lifeng Tian, Vanessa Gonzalez, Iulian Pruteanu, Anne Marie Nelson, Gabriela Plesa, Adam Waxman, Regina M Young, Bruce L Levine, Carl H June, Edward A. Stadtmauer, and Michael C. Milone: Predictors of T Cell Expansion and Clinical Responses Following B-Cell Maturation Antigen-Specific Chimeric Antigen Receptor T Cell Therapy (CART-BCMA) for Relapsed/Refractory Multiple Myeloma (MM) Blood, ASH Annual Meeting, San Diego, CA 132 : #1974,2018.
Ehren Dancy, Alfred L. Garfall, Adam D. Cohen, Joseph A Fraietta, Megan Davis, Bruce L Levine, Don L. Siegel, Edward A. Stadtmauer, Dan T. Vogl, Adam Waxman, Aaron P. Rapoport, Michael C. Milone, Carl H June, and J. Joseph Melenhorst: Clinical Predictors of T Cell Fitness for CAR T Cell Manufacturing and Efficacy in Multiple Myeloma Blood, ASH Annual Meeting, San Diego, CA 132 : #1886,2018.
Trudel S, Lendvai N, Popat R, Voorhees PM, Reeves B, Libby EN, Richardson PG, Anderson Jr. LD, Sutherland HJ, Yong K, Hoos A, Gorczyca MM, Lahiri S, He Z, Austin DJ, Opalinska JB, Cohen AD: Targeting B-Cell Maturation Antigen with GSK2857916 Antibody-Drug Conjugate in Relapsed or Refractory Multiple Myeloma: A Dose-Escalation and Expansion Phase 1 Trial (BMA117159) Lancet Oncology pii: S1470-2045 (18): 30576-X,2018.
Gumber Ramnika, Cohen Jordana B, Palmer Matthew B, Kobrin Sidney M, Vogl Dan T, Wasserstein Alan G, Nasta Sunita D, Bleicher Melissa B, Bloom Roy D, Dember Laura, Cohen Adam, Weiss Brendan M, Hogan Jonathan J: A clone-directed approach may improve diagnosis and treatment of proliferative glomerulonephritis with monoclonal immunoglobulin deposits. Kidney international 94 (1): 199-205,2018.
Cohen Adam D: CAR T Cells and Other Cellular Therapies for Multiple Myeloma: 2018 Update. American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting (38): e6-e15,2018.
Garfall Alfred L, Stadtmauer Edward A, Hwang Wei-Ting, Lacey Simon F, Melenhorst Jan Joseph, Krevvata Maria, Carroll Martin P, Matsui William H, Wang Qiuju, Dhodapkar Madhav V, Dhodapkar Kavita, Das Rituparna, Vogl Dan T, Weiss Brendan M, Cohen Adam D, Mangan Patricia A, Ayers Emily C, Nunez-Cruz Selene, Kulikovskaya Irina, Davis Megan M, Lamontagne Anne, Dengel Karen, Kerr Naseem Ds, Young Regina M, Siegel Donald L, Levine Bruce L, Milone Michael C, Maus Marcela V, June Carl H: Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma. JCI insight 3 (8): 2018.
Waxman Adam J, Clasen Suparna, Hwang Wei-Ting, Garfall Alfred, Vogl Dan T, Carver Joseph, O'Quinn Rupal, Cohen Adam D, Stadtmauer Edward A, Ky Bonnie, Weiss Brendan M: Carfilzomib-Associated Cardiovascular Adverse Events: A Systematic Review and Meta-analysis. JAMA oncology 4 (3): e174519,2018.