Peter S. Klein, MD, PhD

Hematology
Call 800-789-7366
Headshot of Peter S. Klein, MD, PhD
Penn Medicine Provider

About me

  • Director, Physician-Scientist Program
  • Professor of Medicine (Hematology-Oncology)
  • Professor of Medicine in Cell and Developmental Biology

My education and training

  • Medical School: Johns Hopkins University School of Medicine
  • Residency: Massachusetts General Hospital
  • Fellowship: Cambridge Health-Harvard Medical School

Spoken languages

English
English

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Dr. Klein is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

Research

Publications

Valvezan AJ, Huang J, Lengner CJ, Pack M, and PS Klein Oncogenic mutations in Adenomatous Polyposis Coli (Apc) activate mechanistic Target of Rapamycin Complex 1 (mTORC1) , Disease Models and Mechanisms, 7(1): 2014,63-71

Huang J, Nguyen-McCarty M, Hexner EO, Danet-Desnoyers G, and PS Klein Maintenance of Hematopoietic Stem Cells through regulation of Wnt and mTOR Pathways , Nature Medicine, 18: 2012,1778-1785

Valvezan AJ, Zhang FS, Diehl JA, and PS Klein Adenomatous Polyposis Coli (APC) regulates multiple signaling pathways by enhancing glycogen synthase kinase-3 (GSK-3) activity , Journal of Biological Chemistry, 287: 2012,3823-3832

Skirkanich J, Luxardi G, Yang J, Kodjabachian L, and PS Klein An essential role for transcription before the MBT in Xenopus laevis. , Developmental Biology, 357: 2011,478-491

O’Brien WT, Huang J, Buccafusca R, Garskof J, Valvezan AJ, Berry GT, and PS Klein Glycogen synthase kinase-3 is essential for β-arrestin-2 complex formation and lithium-sensitive behaviors in mice. , Journal of Clinical Investigation, 121: 2011,3756-3762

Blythe SA and Klein PS Prepatterning embryonic development: tabula scripta? , Developmental Cell, 21: 2011,977-978

Blythe SA, Cha SW, Tadjuidje E, Heasman J, Klein PS beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2. , Developmental Cell, 19(2): 2010,220-231

Mazumdar J, O'Brien WT, Johnson RS, LaManna JC, Chavez JC, Klein PS, Simon MC O2 regulates stem cells through Wnt/β-catenin signalling. , Nature Cell Biology, 12(10): 2010,1007-13

Huang J, Zhang Y, Bersenev A, O'Brien WT, Tong W, Emerson SG, Klein PS Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice. , Journal of Clinical Investigation, 119(12): 2009,3519-29

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