Paul J. Mather, MD
Cardiology
Accepting new patients
Sees patients age 18 and up
Penn Heart and Vascular Center
View 1 additional location
Schedule onlineCall 215-615-4949
Penn Medicine Provider

About me

  • Physician Leader, Heart Failure Disease Management
  • Director, Faculty Development, Division of Cardiovascular Medicine
  • Professor of Clinical Medicine (Cardiovascular Medicine)

Education and training

  • Medical School: Temple University School of Medicine
  • Residency: Temple University Hospital
  • Fellowship: Temple University Hospital

What my patients think about me

Average Rating

820 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

November 2025
everyone was great!
November 2025
nice visit
October 2025
paul mather is excellent
October 2025
the empathy of the doctor was evident and very helpful to me.

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Dr. Mather is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Dorothea Kehr, Julia Ritterhoff, Manuel Glaser, Lukas Jarosch, Rafael Salazar, Kristin Spaich, Karl Varadi, Jennifer Birkenstock, Michael Egger, Erhe Gao, Walter Koch, Max Sauter, Marc Freichel, Hugo Katus, Norbert Frey, Andreas Jungmann, Cornelius Busch, Paul Mather, Arjang Ruhparwar, Martin Busch, Mirko Völkers, Rebecca Wade, and Patrick Most S100A1ct: a synthetic peptide derived from S100A1 protein improves cardiac performance and survival in pre-clinical heart failure models , CIRCULATION , 151(8): 2025,548-565

Ali A, Pilotti J, Pierson N, Mather PJ Immune Mediated Necrotizing Myopathy with Non-Ischemic Cardiomyopathy: Exploring Molecular Causes of Heart Failure , Journal of the American College of Cardiology, 83(13): 2024,13_Supplement

Paolo Severino, Massimo Mancone, Andrea D’Amato, Marco Valerio Mariani, Silvia Prosperi, Danilo Alunni Fegatelli, Lucia Ilaria Birtolo, Danilo Angotti, Alberto Milanese, Enrico Cerrato, Viviana Maestrini, Carmine Pizzi, Alberto Foà, Annarita Vestri, Alberto Palazzuoli, Carmine Dario Vizza, Paul N. Casale, Paul J. Mather and Francesco Fedele Heart failure ‘the cancer of the heart’: the prognostic role of the HLM score, , ESC Heart Failure, 11(1): 2024,390-399

Olanipekun T, Abe T, Effoe V, Obiora E, Mather P, Echols M, Adedinsewo D Racial Disparities in the Trends and Outcomes of Cardiogenic Shock Complicating Peripartum Cardiomyopathy , JAMA, 5(7): 2022,e2220937

McCaffrey JA, Dhakal BP, Nathan AS, Ortega-Legaspi J, Fiorilli PN, Mather PJ, Supple GE Loss of Right Atrial Pacing Lead Capture Due to Myocardial Infarction Obscuring Diagnosis on Electrogram , JACC Case reports, 4(14): 2022,890-894

Norris M, Molina M, Callaghan K, Wang T, Mather P Utility of Cardiovascular Magnetic Resonance Imaging in Non-HLA Mediated Cardiac Allograft Dysfunction, ISHLT 2022, USA , ISHLT Journal, 41(4): 2022,S417

Abe T, Olanipekun T, Igwe J, Khour M, Olukayode B, Musonge-EFFoe J, Vlaery E, Egbuche O, Mather P, Ghali J Trends, Predictors and Outcomes of Ischemic Stroke Among Patients Hospitalized with Takotsubo Cardiomyopathy , Journal of Stroke and Cerebrovascular Disease, 30(10): 2021

Abe T, Olanipekun T, Igwe J, Khour M, Olukayode B, Musonge-EFFoe J, Vlaery E, Egbuche O, Mather P, Ghali J Trends, Predictors and Outcomes of Ischemic Stroke Among Patients Hospitalized with Takotsubo Cardiomyopathy , Journal of Stroke and Cerebrovascular Disease, 30(10): 2021

Genuardi MV, Mather PJ The Dawn of the Four-Drug Era? SGLT2 Inhibition in Heart Failure with Reduced Ejection Fraction , Ther Adv Cardiovasc Dis 2021, 158: 2021,1-12

Abe T, Eyituoyo HO, De Allie G, Olanipekun T, Effoe VS, Olaosebikan K, Mather P Clinical Outcomes in patients with native valve infective endocarditis and diabetes mellitus , World J Cardiol, 13(1): 2021,11-20