Michael R. Costello, MD

Hematology, Medical Oncology

5.0

(1230)

Accepting new patients

Sees patients age 18 and up

Abramson Cancer Center Exton

View 1 additional location

Make an appointment Call 800-789-7366

Penn Medicine Provider

About me

Medical Director. The Abramson Cancer Center West Chester

My education and training

Medical School: Penn State Milton S. Hershey Medical Center
Residency: Temple University Hospital
Fellowship: Temple University Hospital

Spoken languages

English

Reviews

Average Rating

5.0

1230 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous

May 2026

5.0

dr costello was great.

Anonymous

May 2026

5.0

he is very knowledgeable but also very honest. he does not "sugar coat" what the cancer is doing and the treatment.

Anonymous

May 2026

5.0

he gets to the point

Anonymous

May 2026

5.0

very knowledgeable, efficient and patient

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

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Locations

PRIMARY LOCATION

Abramson Cancer Center Exton

700 West Lincoln Highway, Suite 720
The Commons at Oaklands, Exton, PA, 19341

800-789-7366

Learn about location

Abramson Cancer Center West Chester

Suite 101
440 East Marshall Street, West Chester, PA, 19380

800-789-7366

Learn about location

Penn Medicine hospital privileges

Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Penn Presbyterian Medical Center: On the medical staff, but does not have privileges to treat patients in the hospital.
Chester County Hospital: Has privileges to treat patients in the hospital.

Dr. Costello is a Penn Medicine physician.

Qualifications and experience

Board certifications

Programs

Awards and recognition

Treatments and Conditions

Abnormal bleeding
Abnormal bruising
Abnormal clotting time
Abnormal INR test
Alpha thalassemia
Anemia
Anticardiolipin antibodies
Antiphospholipid antibodies
Antiphospholipid syndrome
Antithrombin deficiency
Aplastic anemia
Arterial thrombosis
Atypical hemolytic uremic syndrome (HUS)
Autoimmune hemolytic anemia
Bernard-Soulier syndrome
Beta thalassemia
Beta thalassemia intermedia
Bleeding disorders in women
Blood clots
Blood coagulation factor IX
Blood coagulation factor VIII
Budd-Chiari syndrome
Cerebral venous sinus thrombosis (CSVT)
Clotting disorders
Cold agglutinin disease
Cryoglobulinemia
Deep vein thrombosis
Disseminated intravascular coagulation
Drug induced thrombocytopenia
Dysfibrinogenemia
Dyskeratosis congenita
Enlarged spleen (Splenomegaly)
Eosinophilia (High blood eosinophil count)
Erythrocytosis
Essential thrombocytosis
Factor II deficiency
Factor V deficiency
Factor V leiden
Factor VII deficiency
Factor X deficiency
Factor XI deficiency
Fanconi anemia (FA)
G6PD deficiency
Glanzmann thrombasthenia
Head and neck cancer
Head and neck lymphoma
Head and neck skin cancer
Head and neck squamous cell carcinoma
Head and neck tumors
Hematoma
Hemochromatosis
Hemoglobin H disease (HbH)
Hemolytic anemia
Hemophilia A
Hemophilia B (Christmas disease)
Heparin-induced thrombocytopenia
Hereditary elliptocytosis
Hereditary hemochromatosis
Hereditary hemorrhagic telangiectasia (HHT)
Hereditary pyropoikilocytosis
Hereditary spherocytosis
High ferritin level
High hematocrit
High hemoglobin
Hypercoagulable states
Hyperfibrinogenemia
Hypergammaglobulinemia
Hypopharyngeal cancer
Immune thrombocytopenic purpura (ITP)
Iron deficiency anemia
Laryngeal cancer
Leukocytosis (High white blood count)
Leukopenia (Low white blood cell count)
Low hemoglobin
Lung cancer
Lung nodule
Lupus anticoagulant disorder
Lymphadenopathy (Enlarged lymph nodes)
Lymphatic diseases
Lymphocytosis (High lymphocyte count)
Lymphopenia (Low lymphocyte count)
Megaloblastic anemia
Menorrhagia (Heavy period)
Mesenteric vein thrombosis
Mesothelioma
Monoclonal gammopathy
Monoclonal gammopathy of undetermined significance
Myelofibrosis
Myeloproliferative disease
Myeloproliferative neoplasms (MPNs)
Nasal cavity cancer
Nasal paranasal sinus cancer
Nasopharyngeal cancer
Neonatal alloimmune thrombocytopenia (NAIT)
Neutropenia (Low neutrophil count)
Non-small cell lung cancer
Oral cancer
Oropharyngeal cancer
Osler-Weber-Rendu syndrome
Pancytopenia (Low blood cell count)
Parathyroid cancer
Paroxysmal nocturnal hemoglobinuria (PNH)
Pernicious anemia
Pituitary cancer
Pituitary tumor
Platelet function disorder
Polycythemia
Polycythemia vera
Porphyria
Portal vein thrombosis (PVT)
Postphlebitic syndrome
Postthrombotic syndrome
Protein C deficiency
Protein S deficiency
Prothrombin gene mutation
Pulmonary embolism
Pure red-cell aplasia (PRCA)
Pyruvate kinase deficiency (PK Deficiency)
Qualitative platelet disorder
Recurrent pregnancy loss
Salivary gland cancer
Sickle cell disease
Skull base tumor
Skull sarcoma
Small cell lung cancer
Spherocytosis
Storage pool disorder
Stroke and blood disorder
Superficial phlebitis
Superficial venous thrombosis
Thalassemia
Throat cancer
Thrombocytopenia (Low platelet count)
Thrombocytosis (High platelet count)
Thrombophilia (Excessive blood clotting)
Thrombotic thrombocytopenic purpura (TTP)
Thyroid cancer
Transfusional iron overload
Transient ischemic attack
Vascular anomaly
Vascular disease
Venous thromboembolism
Vitamin B12 deficiency
Von Willebrand disease

Research

Publications

Cosstello MR, Meropol NJ, Denlinger CS, Engstrom PF, Wright JJ, Li T, McLaughlin S, Beard M, Cimildoro R, Cohen SJ. A phase II trial of the proteasome inhibitor bortezomib in patients with recurrent or metastatic adenocarcinoma of the bile duct or gallbladder (NCI #6135). , Journal of Clinical Oncology, 2009 ASCO Annual Meeting Proceedings (Post Meeting Edition)., 27(155): 2009,e15605

Michael Costello Current Recommendations for Screening for Cervical Cancer , Temple University Hospital Morning Conference Series: 2006

Michael Costello Treatment of Thromboembolic Disease in Oncological Patients , Temple University Hospital Morning Conference Series: 2005

Michael Costello Methicillin Resistant Staph Aureus Infection in a 26 year old patient , Temple University Hospital Morning Conference Series: 2005

Michael R. Costello, MD

About me

My education and training

Spoken languages

Reviews

1230 reviews

Insurance accepted

Aetna

Amerihealth Caritas (Transplant patients only)

Centivo

Cigna Healthcare

Claim Watcher (Homestead/INDECs)

Clover Health

Locations

Abramson Cancer Center Exton

Abramson Cancer Center West Chester

Penn Medicine hospital privileges

Qualifications and experience

Board certifications

Programs

Awards and recognition

Treatments and Conditions

144Conditions

2Treatments

Research