Matthew C. Brennan, MD
Medical Oncology, Hematology
Headshot of Matthew C. Brennan, MD

Matthew C. Brennan, MD

Medical Oncology, Hematology
Accepting new patients
Sees patients age 18 and up
LG Health Physicians Hematology and Medical Oncology
Headshot of Matthew C. Brennan, MD
Penn Medicine Provider

About me

Having practiced medical oncology for over a decade, I’ve had a chance to see exciting breakthroughs and evolving therapeutics that help those affected by cancer live longer and better. 

I practice general medical oncology and benign hematology. My area of additional expertise and interest is genitourinary malignancies—prostate, bladder, kidney, and testicular cancers. Most of the therapies we use today in genitourinary cancers did not exist when I was a student, and I feel optimistic about what the next decade in breakthroughs will bring to the clinic.

I wake up each day excited that I get to be a part of a team at the Ann B. Barshinger Cancer Institute that gets to do great things for the patients we care for. It truly is such an exciting time to be a physician and a privilege to be able to help our community. 

 

My education and training

  • Pennsylvania State University College of MedicineMedical School
  • Thomas Jefferson University HospitalResidency
  • Penn State Milton S. Hershey Medical CenterFellowship

Spoken languages

English
English

Reviews

Average Rating

221 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
September 2026
gd dr
Anonymous
September 2026
he knew what i needed, and explained what all my options are
Anonymous
August 2026
very informative
Anonymous
August 2026
very likeable and friendly

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Lancaster General Hospital: Has privileges to treat patients in the hospital.
Dr. Brennan is a Penn Medicine physician.

Qualifications and experience

Treatments and conditions