Provider Profile | Penn Medicine

Matthew C. Brennan, MD

Hematology, Medical Oncology

4.9

(241)

Accepting new patients

Sees patients age 18 and up

LG Health Physicians Hematology and Medical Oncology

Make an appointment Call 717-544-9400

Penn Medicine Provider

About me

Education and training

Medical School: Pennsylvania State University College of Medicine
Residency: Thomas Jefferson University Hospital
Fellowship: Penn State Milton S. Hershey Medical Center

What my patients think about me

Average Rating

4.9

239 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

January 2026

5.0

great doctor

January 2026

5.0

seems to know his stuff

January 2026

5.0

i feel he is a very good dr. and cares about his patients.

December 2025

5.0

dr brennan listens intently well.

Insurance accepted

Aetna

Amerihealth Caritas (Transplant patients only)

Capital Blue Cross/Capital Advantage Insurance Company

Cigna Healthcare

Claim Watcher (Homestead/INDECs)

Devoted Health Plan

Geisinger Health Plan

HealthAmerica / HealthAssurance, a Coventry Plan

Highmark Blue Shield

Highmark Wholecare (fka Gateway Health)

Humana Medicare

Humana Military (Tricare/Health Net Federal Services)

Imagine Health (Imagine Health 360)

Independence Blue Cross (IBC)

Jefferson Health Plans/Health Partners

Keystone First Health Plan

Medicaid - Pennsylvania

Medicare - Pennsylvania

Oscar Health Plan of PA

PA Health & Wellness

Perennial Advantage

Rail Road Medicare/Palmetto GBA

UnitedHealthcare

UnitedHealthcare Community Plan of PA

UPMC Health Plan

US Family Health Plan

VA Insurance (Veteran's CCN)

My Locations

LG Health Physicians Hematology and Medical Oncology

Ann B. Barshinger Cancer Institute

2102 Harrisburg Pike, Lancaster, PA, 17601

717-544-9400

Learn about location

Penn Medicine hospital privileges

Lancaster General Hospital: Has privileges to treat patients in the hospital.

Dr. Brennan is a Penn Medicine Lancaster General Health physician.

Qualifications and experience

Board certifications

Treatments and Conditions

Abnormal bleeding
Amyloidosis
Anal cancer
Anemia

Antiphospholipid syndrome
Antithrombin deficiency
Aplastic anemia
Autoimmune hemolytic anemia
Beta thalassemia
Bile duct cancer (Cholangiocarcinoma)
Bladder cancer
Blood clots
Blood coagulation factor IX
Blood coagulation factor VIII
Breast cancer
Burkitt's lymphoma
Castleman disease (CD)
Chronic lymphocytic lymphoma
Chronic myeloid leukemia (CML)
Chronic myelomonocytic leukemia (CMML)
Clotting disorders
Cold agglutinin disease
Colon cancer
Colorectal cancer
Cryoglobulinemia
Cutaneous T-cell lymphoma
Deep vein thrombosis
Enlarged spleen (Splenomegaly)
Erythrocytosis
Esophageal cancer
Essential thrombocytosis
Factor V leiden
Fanconi anemia (FA)
G6PD deficiency
Gallbladder cancer
Gastrointestinal cancer
Gastrointestinal stromal tumor
Hairy cell leukemia
Head and neck cancer
Hemolytic anemia
Heparin-induced thrombocytopenia
Hereditary spherocytosis
Hodgkin's lymphoma
Hypercoagulable states
Immune thrombocytopenic purpura (ITP)
Iron deficiency anemia
Kappa light chain disease
Kidney cancer
Langerhans cell histiocytosis
Leukocytosis (High white blood count)
Leukopenia (Low white blood cell count)
Light chain deposition disease
Liver cancer
Lung cancer
Lupus anticoagulant disorder
Lymphopenia (Low lymphocyte count)
Lymphoplasmacytic lymphoma (LPL)
Marginal zone lymphoma
Melanoma skin cancer
Merkel cell skin cancer
Multiple myeloma
Myelodysplastic syndrome (MDS)
Myelofibrosis
Myeloproliferative disease
Neuroendocrine tumors
Neutropenia (Low neutrophil count)
Pancreatic cancer
Pancytopenia (Low blood cell count)
Paroxysmal nocturnal hemoglobinuria (PNH)
Peripheral T-cell lymphoma
Pernicious anemia
Platelet function disorder
Polycythemia
Porphyria
Postthrombotic syndrome
Primary central nervous system lymphoma
Prostate cancer
Protein C deficiency
Protein S deficiency
Prothrombin gene mutation
Pure red-cell aplasia (PRCA)
Rectal cancer
Sarcoma
Sickle cell disease
Skin cancer
Testicular cancer
Thalassemia
Thrombocytopenia (Low platelet count)
Thrombocytosis (High platelet count)
Thrombophilia (Excessive blood clotting)
Thyroid cancer
Vitamin B12 deficiency
Von Willebrand disease

(89)

About me

Education and training

What my patients think about me

239 reviews

Insurance accepted

Aetna

Amerihealth Caritas (Transplant patients only)

Capital Blue Cross/Capital Advantage Insurance Company

Cigna Healthcare

Claim Watcher (Homestead/INDECs)

Devoted Health Plan

Geisinger Health Plan

HealthAmerica / HealthAssurance, a Coventry Plan

Highmark Blue Shield

Highmark Wholecare (fka Gateway Health)

Humana Medicare

Humana Military (Tricare/Health Net Federal Services)

Imagine Health (Imagine Health 360)

Independence Blue Cross (IBC)

Jefferson Health Plans/Health Partners

Keystone First Health Plan

Medicaid - Pennsylvania

Medicare - Pennsylvania

Oscar Health Plan of PA

PA Health & Wellness

Perennial Advantage

Rail Road Medicare/Palmetto GBA

UnitedHealthcare

UnitedHealthcare Community Plan of PA

UPMC Health Plan

US Family Health Plan

VA Insurance (Veteran's CCN)

My Locations

LG Health Physicians Hematology and Medical Oncology

Penn Medicine hospital privileges

Qualifications and experience

Board certifications

Treatments and Conditions

93Conditions