Mark L. Kahn, MD
Sees patients age 18 and up
Penn Medicine Provider

About me

  • Edward S. Cooper, M.D./Norman Roosevelt and Elizabeth Meriwether McLure Professor
  • Professor of Cell and Developmental Biology

Insurance accepted

My Locations

Qualifications and experience

Treatments and Conditions

My research

Pace JA, Goddard LM, Hong CC, Wang L, Yang J, Chen M, Xu Y, Dominguez MH, Gao S, Chen X, Mericko-Ishizuka P, Tan C, Kume T, Yu W, Tan K, Hancock WW, Ferrari G, Kahn ML Hemodynamic forces prevent myxomatous valve disease in mice through KLF2/4 signaling , J Clin Invest: 2025


Chen X, Tober J, Dominguez M, Tang AT, Bockman J, Yang J, Mani S, Lee CN, Chen M, Thillaikumaran T, Mericko-Ishizuka P, Mainigi M, Speck NA, Kahn ML Lineage tracing studies suggest that the placenta is not a de novo source of hematopoietic stem cells , PLoS Biol: 2025


Jabarkheel R, Li L, Frankfurter M, Zhang DY, Gajjar A, Muhammad N, Srinivasan VM, Burkhardt JK, Kahn M Untangling sporadic brain arteriovenous malformations: towards targeting the KRAS/MAPK pathway , Front Surg.: 2024


Ren J, Cui Z, Jiang C, Wang L, Guan Y, Ren Y, Zhang S, Tu T, Yu J, Li Y, Duan W, Guan J, Wang K, Zhang H, Xing D, Kahn ML, Zhang H, Hong T GNA14 and GNAQ somatic mutations cause spinal and intracranial extra-axial cavernous hemangiomas , Am J Hum Genet: 2024


Yuki K, Vallon M, Ding J, Rada CC, Tang AT, Vilches-Moure JG, McCormick AK, Henao Echeverri MF, Alwahabi S, Braunger BM, Ergün S, Kahn ML, Kuo CJ GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism , Development: 2024


Kahn ML CCM Function in the Heart: Working From Outside-In Rather Than Inside-Out , JACC Basic Transl Sci: 2024


Li Y, Girard R, Srinath A, Cruz DV, Ciszewski C, Chen C, Lightle R, Romanos S, Sone JY, Moore T, DeBiasse D, Stadnik A, Lee JJ, Shenkar R, Koskimäki J, Lopez-Ramirez MA, Marchuk DA, Ginsberg MH, Kahn ML, Shi C, Awad IA Transcriptomic signatures of individual cell types in cerebral cavernous malformation , Cell Commun Signal: 2024


Ocskay Z, Bálint L, Christ C, Kahn ML, Jakus Z CCBE1 regulates the development and prevents the age-dependent regression of meningeal lymphatics , Biomed Pharmacother: 2024


Gao S, Thillaikumaran T, Dominguez MH, Giang W, Hayes K, Chen X, Pace J, Bockman J, Jathan D, Sung D, Narayan S, Frankfurter M, Mericko-Ishizuka P, Yang J, Castro M, Potente M, Kahn ML YAP/TAZ signaling in allantois-derived cells is required for placental vascularization , bioRxiv: 2024


Li L, Ren AA, Gao S, Su YS, Yang J, Bockman J, Mericko-Ishizuka P, Griffin J, Shenkar R, Alcazar R, Moore T, Lightle R, DeBiasse D, Awad IA, Marchuk DA, Kahn ML, Burkhardt JK mTORC1 Inhibitor Rapamycin Inhibits Growth of Cerebral Cavernous Malformation in Adult Mice , Stroke: 2023


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