Mark Stephen Etherington, MD

Endocrine and Oncologic Surgery
Accepting new patients
Sees patients age 18 and up
Penn Endocrine and Oncologic Surgery Washington Square 20th Floor
View 1 additional location
Schedule onlineCall 215-829-8461
Headshot of Mark Stephen Etherington, MD
Penn Medicine Provider

About me

  • Assistant Professor of Surgery at the Hospital of the University of Pennsylvania

I am a gastrointestinal and hepatopancreatobiliary cancer surgeon with a focus on robotic, minimally invasive surgical techniques.

I specialize in the surgical treatment of abdominal cancers including pancreatic cancer, primary and metastatic tumors of the liver, bile duct tumors, stomach cancer, small bowel cancer, neuroendocrine tumors, GISTs, and retroperitoneal sarcomas. I perform minimally invasive, robotic Whipple procedure for the treatment of pancreatic cancer.

My education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: University of Pennsylvania Health System
  • Fellowship: University of Pittsburgh Medical Center

Watch video featuring Mark Stephen Etherington, MD on YouTube

Spoken languages

English
English

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Etherington is a Penn Medicine physician. In New Jersey, providers are affiliated with Penn Medicine through Clinical Health Care Associates of New Jersey or Princeton Healthcare Affiliated Physicians, PC.

Qualifications and experience

Treatments and Conditions

Research

Publications

Farooq MS, Vargas GM, Simons RA, Jona A, Shafique N, Folkert IW, Miura JT, Karakousis GC, Roses RE, Etherington MS Robotic surgery for small bowel neuroendocrine tumors is associated with greater nodal harvest compared to laparoscopic surgery , Surgery, 194: 2026

Farooq MS, Jona A, VArgas GM, Simons RA, Miura JT, Karakousis GC, Etherington MS Patient selection, practice patterns, and perioperative outcomes for robotic splenectomy: a contemporary ACS-NSQIP analysis , Surg Endosc: 2026

Beniwal PC, Farooq MS, Vargas GM, Simons RA, Etherington MS, Miura JT, Karakousis GC. Marital Status Is Associated With Treatment Attainment in Pancreatic Adenocarcinoma , J Surg Oncol: 2026

Farooq MS, Roses RE, Karakousis GC, Etherington MS. Patient selection, utilization trends, and short-term postoperative outcomes for minimally invasive versus open resection of small bowel neuroendocrine tumors , J Gastrointest Surg., 6(102218): 2025

McVey JC, Munoz N, El Jack AK, Etherington MS, Lee MK 4th, Vollmer CM Jr, DeMatteo RP, Roses RE Predictors of malignancy in patients undergoing surgery for Mirizzi syndrome , J Gastrointest Surg, 10(29): 2025

Etherington MS, Gajdos C More Evidence for Centralization of Care for Hepatocellular Carcinoma , J Natl Compr Cancer Netw, 23(8): 2025

Etherington MS, Gajdos C. Invited commentary on "Parenchymal-sparing hepatectomy vs single-stage major hepatectomy for bilateral colorectal liver metastases: a higher rate of microscopically positive margins is not associated with increased local recurrence after parenchymal-sparing hepatectomy. Is it time to rethink surgical approaches to multifocal bilateral colorectal liver metastasis?" , J Gastrointest Surg, 29: 2025,102116

Etherington MS, Karakousis GC. Circulating Micro-RNA as a Predictive Biomarker for Radiation Response in Pancreas Cancer , Ann Surg Oncol, 32(2): 2025

Etherington MS, Geller DA Minimally invasive vs. open liver resections for hepatocellular carcinoma and colorectal cancer liver metastases , Surgery: Evidence Based Practice, 2d Edition: 2024 (in press)

Etherington MS, Handzel R, Ongchin M, Choudry MH, Tohme ST, Paniccia A, Lee KK, Zureikat A, Geller DA Remnant completion cholecystectomy is on the rise: Don't three-putt it , HPB (Oxford), 26(8): 2024,1072-1074