Lucie Guo, MD, PhD
Ophthalmology
Accepting new patients
Sees patients age 18 and up
Scheie Eye Institute Perelman
View 1 additional location
Penn Medicine Provider

About me

  • Assistant Professor of Ophthalmology

Education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: Santa Clara Valley Medical Center
  • Residency: Stanford University
  • Fellowship: Stanford University

What my patients think about me

Average Rating

97 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
February 2026
great visit
Anonymous
February 2026
clear explanations
Anonymous
February 2026
professional
Anonymous
February 2026
waiting time too long

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Guo is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Thakur S, Guo LY, Mruthyunjaya P. An Unusual Pigmented Lesion , Ophthalmology, 132(1): 2025,e14


Soetikno BT, Ghoraba H, Brant A, DeBoer C, Guo L, Shue A, Hartnett ME. Retinal racemose hemangioma presenting with a chorioretinal anastomosis , Am J Ophthalmol Case Rep, 36(16): 2024,102188


Guo LY, Mishra K, Leung LB. Severe progression of pentosan maculopathy over a decade , Am J Ophthalmol Case Rep, 30(8): 2023,101826


Kempton HR, Love KS, Guo LY, Qi LS. Scalable biological signal recording in mammalian cells using Cas12a base editors , Nat Chem Biol, 18(7): 2022,742-750


Guo LY, Bian J, Davis AE, Liu P, Kempton HR, Zhang X, Chemparathy A, Gu B, Lin X, Rane DA, Xu X, Jamiolkowski RM, Hu Y, Wang S, Qi LS. Multiplexed genome regulation in vivo with hyper-efficient Cas12a , Nat Cell Biol, 24(4): 2022,590-600


Guo LY, Jamiolkowski RM, Hassan M, Leng T. A buoyant mass in the brain: Intraventricular migration of silicone oil , Am J Ophthalmol Case Rep, 25(3): 2022,101399


Zasadzińska E, Huang J, Bailey AO, Guo LY, Lee NS, Srivastava S, Wong KA, French BT, Black BE, Foltz DR. Inheritance of CENP-A Nucleosomes during DNA Replication Requires HJURP , Dev Cell, 47: 2018,348-362


Stankovic A, Guo LY, Mata JF, Bodor DL, Cao XJ, Bailey AO, Shabanowitz J, Hunt DF, Garcia BA, Black BE, Jansen LET. A Dual Inhibitory Mechanism Sufficient to Maintain Cell-Cycle-Restricted CENP-A Assembly , Mol Cell, 65(19): 2017,231-246


Falk SJ, Guo LY, Sekulic N, Smoak EM, Mani T, Logsdon GA, Gupta K, Jansen LE, Van Duyne GD, Vinogradov SA, Lampson MA, Black BE. Chromosomes. CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere , Science, 348(6235): 2015,699-703


Jamiolkowski RM, Guo LY, Li YR, Shaffer SM, Naji A. Islet transplantation in type I diabetes mellitus , Yale J Biol Med, 85(1): 2012,37-43