Lucie Guo, MD, PhD

Ophthalmology
Accepting new patients
Sees patients age 18 and up
Scheie Eye Institute Perelman
View 1 additional location
Make an appointmentCall 215-662-8100
Headshot of Lucie Guo, MD, PhD
Penn Medicine Provider

About me

  • Assistant Professor of Ophthalmology

My education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: Santa Clara Valley Medical Center
  • Residency: Stanford University
  • Fellowship: Stanford University

Spoken languages

English
English

Reviews

Average Rating

138 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
May 2026
she knew her stuff and explained it to us, so we understood.
Anonymous
April 2026
she is knowledgeable and personable.
Anonymous
April 2026
caring, careful, respectful and professional
Anonymous
April 2026
the provider repaired my retina and did a great job

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Guo is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

Research

Publications

Lucie Y Guo, Daniel SW Ting From black boxes to biomarkers: artificial intelligence in surgical retina , Ophthalmology Retina (in press): 2026

Melissa Yuan, Amer Alsoudi, Purna Nangia, Lucie Guo, Ahmad Al-Moujahed, Chase A Ludwig, Karen M Wai, Prithvi Mruthyunjaya, Ehsan Rahimy Prevalence and incidence of mental health disorders in patients with inherited retinal diseases: a population-based study , J AAPOS: 2026

Anas Alkhabaz, Joseph Waiguru, Lucie Y Guo, Jared Sokol, Carolyn Pan, Charles DeBoer Regression of a Subretinal Proliferation Band with Intravitreal Methotrexate in Recurrent Retinal Detachment , Retinal Cases and Brief Reports: 2026

Anas Alkhabaz, Lucie Y Guo, Charles DeBoer Foreign Body Presenting as Golden Hypopyon , Surgeries: 2025

Thakur S, Guo LY, Mruthyunjaya P. An Unusual Pigmented Lesion , Ophthalmology, 132(1): 2025,e14

Soetikno BT, Ghoraba H, Brant A, DeBoer C, Guo L, Shue A, Hartnett ME. Retinal racemose hemangioma presenting with a chorioretinal anastomosis , Am J Ophthalmol Case Rep, 36(16): 2024,102188

Guo LY, Mishra K, Leung LB. Severe progression of pentosan maculopathy over a decade , Am J Ophthalmol Case Rep, 30(8): 2023,101826

Kempton HR, Love KS, Guo LY, Qi LS. Scalable biological signal recording in mammalian cells using Cas12a base editors , Nat Chem Biol, 18(7): 2022,742-750

Guo LY, Bian J, Davis AE, Liu P, Kempton HR, Zhang X, Chemparathy A, Gu B, Lin X, Rane DA, Xu X, Jamiolkowski RM, Hu Y, Wang S, Qi LS. Multiplexed genome regulation in vivo with hyper-efficient Cas12a , Nat Cell Biol, 24(4): 2022,590-600

Guo LY, Jamiolkowski RM, Hassan M, Leng T. A buoyant mass in the brain: Intraventricular migration of silicone oil , Am J Ophthalmol Case Rep, 25(3): 2022,101399