Lillias H. Maguire, MD
Colon and Rectal Surgery
Accepting new patients
Sees patients age 18 and up
Penn Colon and Rectal Surgery Perelman
Schedule onlineCall 215-662-2078
Penn Medicine Provider

About me

  • Director of Research, Division of Colon and Rectal Surgery
  • Measey Surgical Faculty Career Development Endowed Professor
  • Assistant Professor of Surgery

Education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: Massachusetts General Hospital
  • Fellowship: University of Minnesota Hospitals

What my patients think about me

Average Rating

178 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

October 2025
excellent dr
October 2025
excellent doctor
October 2025
didn't have to wait long after she was available
October 2025
inspired confidence

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Maguire is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Neylan CJ, Levin MG, Hartmann K, Beigel K, Khodursky S, DePaolo JS, Abramowitz S, Furth EE, Heuckeroth RO, Damrauer SM, Maguire LH Genome-wide association meta-analysis identifies 126 novel loci for diverticular disease and implicates connective tissue and colonic motility , medRxiv: 2025 (Preprint)

Ueland TE, Shelley JP, Mosley JD, Robinson JR, Gamazon ER, Maguire LH, Peek R, Hawkins AT Plasma proteomic signatures for diverticulitis risk stratification , Journal of Surgical Research: 2025 (Epub)

Ma W, Ha J, Neylan CJ, Munro H, Skerrett D, Downie JM, Sevilla-González M, Steinwandel M, Mumma M, Zheng W, Maguire LH, Giovannucci EL, Strate LL, Chan AT Lifestyle factors, genetic susceptibility and risk of incident diverticulitis: An integrated analysis of four prospective cohort studies and electronic health records-linked biobank , Gut: 2025 (Epub)

Neylan CJ, Bercz A, Regenbogen SE, Huang EH, Smith JJ, Maguire LH, Mitchem JB Appraising a CREATEive surgeon-scientist initiative: Impact and future directions , Diseases of the Colon & Rectum, 68(6): 2025,656-657

Roberson JL, Passman JE, Lee MK 4th, Singhal S, Kelz R, Morris JB, Maguire LH Resident self-efficacy in grantsmanship lags behind key funding deadlines , Journal of Surgical Education, 81(12): 2024,103280

Roberson JL, Neylan CJ, Judy R, Walker V, Tsao PS, Damrauer SM, Maguire LH Critical genes in genitourinary embryogenesis are related to the development of adult hydrocele , Science Reports, 14(1): 2024,30314

Ueland TE, Mosley J, Robinson JR, Peek R, Gamazon ER, Maguire LH, Neylan C, Hoffman R, Hawkins AT Nature, nurture or both? Genetic risk, healthy lifestyle, and severe diverticulitis , Journal of the American College of Surgeons, 239(5 Suppl 1): 2024,S94-S95

Neylan C, DePaolo J, Levin M, Roberson J, Damrauer SM, Maguire LH The relationship between the microbiome and diverticular disease: A Mendelian randomization study , Journal of the American College of Surgeons, 239(5 Suppl 1): 2024,S103

Lopez K, Maguire LH Structural alterations in diverticular disease , Clinics in Colon & Rectal Surgery, 38(4): 2024,249-252

Maguire LH Innovations and updates in diverticulitis , Clinics in Colon & Rectal Surgery, 38(4): 2024,239-240