- Alport's syndrome
- Angiomyolipoma of the kidney
- Anti GBM disease
- C3 nephropathy
- Fibrillary GN
- Focal segmental glomerulosclerosis
- Glomerulonephritis
- Goodpasture's syndrome
- Granulomatosis with polyangiitis associated kidney disease
- Henoch-Schoenlein Purpura related kidney disease
- HUS
- Hypophosphatemia
- IgA Nephropathy
- Infectious GN
- Interstitial nephritis
- Lupus nephritis
- Membranoproliferative GN
- Membranous GN
- Microalbuminuria
- Microscopic polyangiitis (MPA)
- Minimal change disease
- Nephrotic syndrome
- Polyangiitis
- Proteinuria
- Thrombocytopenic purpura
- Vasculitis: ANCA
Lawrence B. Holzman, MD
About me
- Professor of Medicine (Renal-Electrolyte and Hypertension)
- Professor of Medicine in Pediatrics
My education and training
- Medical School: University of Medicine and Dentistry of New Jersey
- Residency: Medical College of Pennsylvania
- Fellowship: University of Michigan Health
Spoken languages
Reviews
157 reviews
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Insurance accepted
- Aetna Advantra Cares D-SNP
- Aetna Advantra Credit Value
- Aetna Advantra Eagle HMO
- Aetna Advantra Eagle POS
- Aetna Advantra Premier Plus PPO
- Aetna Advantra Value
- Aetna Advantra Value Plus
- Aetna APCN Plus (Multi-Tier)
- Aetna Better Health Kids (CHIP) - DH Only
- Aetna Flexible Five
- Aetna Freedom Core
- Aetna Gold
- Aetna HMO
- Aetna Philly Prime
- Aetna POS
- Aetna PPO APCN
- Aetna Premier
- Aetna Premier Plus
- Aetna Savings Plus
- Aetna Signature Administrators
- Aetna Student Health Plan PPO
- Aetna Upfront Advantage
- First Health HMO
- First Health POS
- First Health PPO
- Meritain - Aramark (Other)
- Meritain - Aramark (Pennsylvania Premier Medical Plan)
- Americhealth Caritas of PA VIP - LGH Only
- Amerihealth Caritas (Transplant patients only)
- Amerihealth Caritas of PA - LGH Only
- Centivo EPO
- Cigna Healthcare EPO
- Cigna Healthcare HMO
- Cigna Healthcare POS
- Cigna Healthcare PPO
- Claim Watcher (Homestead/ INDECs) Open Access
- Clover Health Choice
- Clover Health Choice Value PPO
- Clover Health Classic HMO
- Clover Health Value
Locations
Penn Medicine hospital privileges
- Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
- Penn Presbyterian Medical Center: On the medical staff, but does not have privileges to treat patients in the hospital.
Qualifications and experience
- Internal Medicine, 1987
- American Association for the Advancement of Science, National
- American Association of Physicians, National
- American College of Physicians, National
- American Heart Association/American Stroke Association, National
- American Society for Cell Biology, National
- American Society for Clinical Investigation, National
- American Society for Microbiology, National
- American Society of Nephrology, National
- Kidney Council, American Heart Association, National
- NIH/NIDDK External Expert Panel, National
- SUGARNSALT Study Data and Safety Monitoring Board, International
- Recognized annually in Philadelphia Magazine's Top Docs issue from 2018 through 2025
Treatments and conditions
Research
Publications
Spinale Joann M, Mariani Laura H, Kapoor Shiv, Zhang Jidong, Weyant Robert, Song Peter X, Wong Hetty N, Troost Jonathan P, Gadegbeku Crystal A, Gipson Debbie S, Kretzler Matthias, Nihalani Deepak, Holzman Lawrence B A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease. , Kidney international, 87(3): 2015,564-74
Gadegbeku CA, Gipson DS, Holzman LB, Ojo AO, Song PXK, Barisoni L, Sampson MG, Kopp JB, Lemley KV, Nelson PJ, Lienczewski CC, Adler SG, Appel GB, Cattran DC, Choi MJ, Contreras G, Dell KM, Fervenza FC, Gibson KL, Greenbaum LA, Hernandez JD, Hewitt SM, Hingorani SR, Hladunewich M, Hogan MC, Hogan SL, Kaskel FJ, Lieske JC, Meyers KEC, Nachman PH, Nast CC, Neu AM, Reich HN, Sedor JR, Sethna CB, Trachtman H, Tuttle KR, Zhdanova O, Zilleruelo GE, Kretzler M Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach. , Kidney Int, 83(4): 2013,749-56
George B, Verma R, Soofi AA, Garg P, Zhang J, Park T, Giardino L, Ryzhova L, Johnstone DB, Wong H, Nihalani D, Salant DJ, Hanks SK, Curran T, Rastaldi MP, and Holzman LB Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mice , J Clin Invest, 122(2): 2012,674-92
Deepak N, Wong H, Verma R, Holzman LB Src Family Kinases Directly Regulate JIP1 Module Dynamics and Activation , Mol Cell Biol, 27(7): 2007,2431-2441
Verma R, Kovari I, Abdul S, Nihalani D, Patrie K, Holzman LB Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization , J Clin Invest, 116(5): 2006,1346-1359
Moeller MJ, Soofi A, Sanden S, Floege J, Kriz W, Holzman LB An efficient system for tissue-specific over-expression of transgenes in podocytes in vivo , Am J Physiol Renal Physiol, 289(2): 2005,F481-F488
Moeller MJ, Soofi A, Watzel C, Kriz W, Holzman LB Protocadherin FAT1 binds Ena/VASP and is necessary for lamellipodial dynamics, cell polarization, and cell migration , EMBO J, 23(19): 2004,3769-3779
Holzman LB, St. John P, Kovari I, Verma R, Holthofer H, Abrahamson D Nephrin is localized to the slit pore of the glomerular epithelial cell , Kidney Intl, 56(4): 1999,1481-1491
Nihalani D, Meyer D, Pajni S, Holzman LB Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components , EMBO J, 20(13): 2001,3447-3458
Holzman LB, Merritt S, Fan G Identification, molecular cloning, and characterization of Dual Leucine Zipper Kinase: a novel serine/threonine kinase that defines a second subfamily of MLK kinases , J Biol Chem, 269(49): 1994,30808-30817