About me
- Associate Director, Penn Center for Viral Hepatitis
- Professor of Medicine (Gastroenterology)
Education and training
- Medical School: Medical College of Pennsylvania
- Residency: St. Francis Medical Center
- Residency: Inspira Medical Center - Woodbury
- Residency: Medical College of Pennsylvania
- Fellowship: UC San Diego Medical Center
My Locations
Penn Medicine hospital privileges
- Hospital of the University of Pennsylvania: On the medical staff, but does not have privileges to treat patients in the hospital.
Qualifications and experience
- AIDS and Related Research Review Group, National
- American Association for the Study of Liver Disease (AASLD), National
- American Gastroenterology Association, National
- American Society for Clinical Investigation, National
- Associate Chief of Staff for Research Council, VA Office of R&D, National
- Digestive Diseases Week (AGA Annual Meeting), National
- International Coalition to Eliminate HBV (ICE HBV), International
- Irish Health Research Board, International
- National Center for Research Resources, General Clinical Research Center, National
- NIH GMA2 Member Conflict Study Section Review Committees, NIH Loan Repayment Program (NIAID), National
- NIH/NIDDK Special Grants Review Committees, National
- VA Office of R&D, National
- VA VISN4 Research Committee, Local
Treatments and Conditions
My research
Wendland ZD, Teerlink CC, Pridgen KM, Lo S, Sayed C, van Straalen KR, Tcheandjieu C, Tsao PS, Chang KM, Li Y, Mohlke KL, Sun Q, Lynch JA, Goldfarb N. A genome-wide association study of hidradenitis suppurativa from the VA's Million Veteran Program , Dermatology: 2026
Mureddu M, Pelusi S, Jamialahmadi O, Vujkovic M, Miano L, Eidgah Torghabehei H, Ronzoni L, Malvestiti F, Saracino M, Periti G, Moretti V, Teerlink CC, Lynch JA, Tsao PS, Johnson JP, La Mura V, Dilena R, Alqahtani SA, Cherubini A, Russo FP, D'Ambrosio R, Fraquelli M, Petta S, Miele L, Vespasiani-Gentilucci U, Bugianesi E, Mancina RM, Parini P, Prati D, Chang KM, Schneider CV, Romeo S, Valenti LV. Carriage of rare APOB variants predisposes to severe steatotic liver disease and hepatocellular carcinoma , J Clin Invest: 2026
Sideris K, Nelson TJ, Brinker L, Gao A, Tcheandjieu C, Kyriakopoulos CP, Berlowitz D, Hull L, Ferraro JP, Agiri FY, Pridgen KM, Roblin S, Joseph J, Damrauer SM, Chang KM, Teerlink CC, Stehlik J, Carter S, Lynch JA. Systemic Manifestations and Mortality Risk in Transthyretin V142I Variant Carriers: A Million Veteran Program Analysis , JACC CardioOncol: 2026
Bermudez F, Shakt G, Bowles A, Alba P, Dinatale T, Chang KM, Tsao PS, Lynch J, Dochtermann D, Pyarajan S, Small A, Levin MG, Damrauer SM. Multipopulation Genome-Wide Association Study Identifies Novel Loci for Bicuspid Aortic Valve and Reveals Shared Genetic Architecture With Aortopathies , Circ Genom Precis Med: 2026
Sideris K, Nelson TJ, Brinker L, Gao A, Tcheandjieu C, Kyriakopoulos CP, Berlowitz D, Hull L, Ferraro JP, Agiri FY, Pridgen KM, Roblin S, Joseph J, Levin MG, Damrauer SM, Chang KM, Teerlink CC, Stehlik J, Carter S, Lynch JA. Risk of Systemic Manifestations in Homozygous Carriers of the Transthyretin V142I Variant: A Million Veteran Program Analysis , J Am Heart Assoc, 14: 2025,e044923
Maamari DJ, Biddinger KJ, Jurgens SJ, Rämö JT, Gaziano L, Zheng A, Challa SP, Hayes D, Gongora CA, Choi SH, Chang KM, Tsao PS, Arany Z, Thavendiranathan P, Huffman JE, Fahed AC, Sarma AA, Neilan TG, Khera AV, Ellinor PT, Aragam KG. Polygenic Susceptibility in Peripartum, Alcohol-Induced, and Cancer Therapy-Related Cardiomyopathies , JAMA Cardiol, 10: 2025,1138-1146
Guo B, Cai Y, Kim D, Smit RAJ, Wang Z, Iyer KR, Hilliard AT, Haessler J, Tao R, Broadaway KA, Wang Y, Pozdeyev N, Stæger FF, Yang C, Vanderwerff B, Patki AD, Stalbow L, Lin M, Rafaels N, Shortt J, Wiley L, Stanislawski M, Pattee J, Davis L, Straub PS, Shuey MM, Cox NJ, Lee NR, Jørgensen ME, Bjerregaard P, Larsen C, Hansen T, Moltke I, Meigs JB, Stram DO, Yin X, Zhou X, Chang KM, Clarke SL, Guarischi-Sousa R, Lankester J, Tsao PS, Buyske S, Graff M, Raffield LM, Sun Q, Wilkens LR, Carlson CS, Easton CB, Liu S, Manson JE, Marchand LL, Haiman CA, Mohlke KL, Gordon-Larsen P, Albrechtsen A, Boehnke M, Rich SS, Manichaikul A, Rotter JI, Yousri NA, Irvin RM; biobank at the Colorado Center for Personalized Medicine (CCPM); VA Million Veteran Program (MVP); Gignoux C, North KE, Loos RJF, Assimes TL, Peters U, Kooperberg C, Raghavan S, Highland HM, Darst BF. Polygenic risk score for type 2 diabetes shows context-dependent effects across populations , Nat Commun, 16: 2025,8632
Callans LE, Ivey KL, Chang KM, Kaplan DE; VA Million Veteran Program. Diet composition impacts the natural history of steatotic liver disease , Hepatol Commun, 9: 2025,e0754
Adkar SS, Lynch J, Choi RB, Roychowdhury T, Judy RL, Paruchuri K, Go DC, Bamezai S, Cabot J, Sorondo S, Levin MG, Milewicz DM, Willer CJ, Natarajan P, Pyarajan S, Chang KM, Damrauer S, Tsao P, Skirboll S, Leeper NJ, Klarin D. Dissecting the Genetic Architecture of Intracranial Aneurysms , Circ Genom Precis Med: 2025
Chanfreau-Coffinier C, Friede KA, Plomondon ME, Lee KM, Lu Z, Dinatale T, DuVall SL, Vassy JL, Waldo SW, Cleator JH, Maddox TM, Rader DJ, Assimes TL, Damrauer SM, Tsao PS, Chang KM, Voora D, Lynch JA, Giri J; VA Million Veteran Program; Tuteja S. CYP2C19 Polymorphisms and Clinical Outcomes Following Percutaneous Coronary Intervention in the Million Veteran Program , Clin Pharmacol Ther: 2025