Penn Medicine Provider
Radiation Oncology
Keith Cengel, MD, PhD
5.0
(45)
Accepting new patients
Sees patients age 18 and up
Penn Radiation Oncology Perelman - 2nd Floor
View 2 additional locations

About me

  • Executive Director, Penn Mesothelioma and Pleural Diseases Program
  • Director, Photodynamic Therapy Program
  • Professor of Radiation Oncology at the Hospital of the University of Pennsylvania

Education and training

  • Medical School: University of Illinois School of Medicine
  • Residency: University of Illinois
  • Residency: Hospital of the University of Pennsylvania

What my patients think about me

Average Rating
5.0

45 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

June 2025
5.0
5.0
great doctor. trust him with my life
January 2025
5.0
5.0
i cannot say enough great things about dr. cengel.
January 2025
5.0
5.0
dr. cengel is very knowledgeable and explains things well.
January 2025
5.0
5.0
never feel rushed, very knowledgeable

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Chester County Hospital: Has privileges to treat patients in the hospital.
Dr. Cengel is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Jenna Rocchetti 1, Nikhil Yegya-Raman 1, Michelle Iocolano 1, William P Levin 1, Keith A Cengel 1, Jeffrey Bradley 1, Steven J Feigenberg 1, Cole Friedes 2 Salvage thoracic reirradiation for recurrent non-small cell lung cancer: Clinical efficacy and the impact of consolidative immunotherapy , Radiother Oncol : 2025


Seyyedeh Azar Oliaei Motlagh 1, François Vander Stappen 2, Michele M Kim 1, Rudi Labarbe 2, Lucian Hotoiu 2, Arnaud Pin 2, Rasmus Nilsson 3, Erik Traneus 3, Keith A Cengel 1, Wei Zou 1, Boon-Keng Kevin Teo 1, Lei Dong 1, Eric S Diffenderfer 1 Verification of dose and dose rate for quality assurance of spread-out-Bragg-peak proton FLASH radiotherapy using machine log files , Med Phys : 2025


Gwendolyn M Cramer 1, Richard W Davis 4th 1, Emmanouil Papasavvas 2, Astero Klampatsa 3, Joann M Miller 1, Shirron Carter 1, Ruth Ikpe 1, Min Yuan 1, Sandy Widura 2, R Sonali Majumdar 2, Sally McNulty 1, Mary Putt 4, Andrew V Kossenkov 2, Luis J Montaner 2, Sunil Singhal 5, Edmund K Moon 3, Steven M Albelda 3, Keith A Cengel 1, Theresa M Busch 1 PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma , Cancer Res Commun: 2025


Ioannis I Verginadis 1, Anastasia Velalopoulou 1, Michele M Kim 1, Kyle Kim 1, Ioannis Paraskevaidis 1, Brett Bell 2, Seyyedeh Azar Oliaei Motlagh 1, Antoneta Karaj 3, Esha Banerjee 4, Giovanni Finesso 4, Charles-Antoine Assenmacher 4, Enrico Radaelli 4, Jiawei Lu 5, Yuewei Lin 5, Mary E Putt 3, Eric S Diffenderfer 1, Chandan Guha 2, Ling Qin 5, James M Metz 1, Amit Maity 1, Keith A Cengel 1, Constantinos Koumenis 1, Theresa M Busch 6 FLASH proton reirradiation, with or without hypofractionation, reduces chronic toxicity in the normal murine intestine, skin, and bone , Radiother Oncol : 2025


Hongjing Sun 1 2, Michele M Kim 1, Yi Hong Ong 1, Andreea Dimofte 1, Sunil Singhal 3, Theresa M Busch 1, Keith A Cengel 1, Timothy C Zhu 1 Comprehensive reanalysis of light fluence distribution in pleural photodynamic therapy using standardized anatomical coordinates , Photochem Photobiol : 2025


Sun H, Ong Y, Kim MM, Dimofte A, Singhal S, Cengel KA, Yodh AG, Zhu TC. A Comprehensive Study of Reactive Oxygen Species Explicit Dosimetry for Pleural Photodynamic Therapy , Antioxidants (Basel), 13: 2024,1436


Verginadis II, Velalopoulou A, Kim MM, Kim K, Paraskevaidis I, Bell B, Oliaei Motlagh SA, Karaj A, Banerjee E, Finesso G, Assenmacher CA, Radaelli E, Lu J, Lin Y, Putt ME, Diffenderfer ES, Guha C, Qin L, Metz JM, Maity A, Cengel KA, Koumenis C, Busch TM. FLASH proton reirradiation, with or without hypofractionation, mitigates chronic toxicity in the normal murine intestine, skin, and bone , bioRxiv: 2024


Yegya-Raman N, Berman AT, Ciunci CA, Friedes C, Berlin E, Iocolano M, Wang X, Lai C, Levin WP, Cengel KA, O'Reilly SE, Cohen RB, Aggarwal C, Marmarelis ME, Singh AP, Sun L, Bradley JD, Plastaras JP, Simone CB 2nd, Langer CJ, Feigenberg SJ. Phase 2 Trial of Consolidation Pembrolizumab After Proton Reirradiation for Thoracic Recurrences of Non-Small Cell Lung Cancer , Int J Radiat Oncol Biol Phys, 119: 2024,56-65


Chowdhury P, Velalopoulou A, Verginadis II, Morcos G, Loo PE, Kim MM, Motlagh SAO, Shoniyozov K, Diffenderfer ES, Ocampo EA, Putt M, Assenmacher CA, Radaelli E, Lu J, Qin L, Liu H, Leli NM, Girdhani S, Denef N, Vander Stappen F, Cengel KA, Busch TM, Metz JM, Dong L, Lin A, Koumenis C. Proton FLASH radiotherapy ameliorates radiation-induced salivary gland dysfunction and oral mucositis and increases survival in a mouse model of head and neck cancer , Mol Cancer Ther, 23: 2024,877-889


Friedes C, Iocolano M, Lee SH, Li B, Duan L, Levin WP, Cengel KA, Sun LL, Aggarwal C, Marmarelis ME, Doucette A, Cohen RB, Xiao Y, Langer CJ, Bradley J, Feigenberg SJ, Yegya-Raman N. Patterns of Failure, Low-Volume Relapse, and Subsequent Ablative Management in Locally Advanced Non-Small Cell Lung Cancer Treated With Definitive Chemoradiation and Consolidation Immune Checkpoint Inhibitors , Int J Radiat Oncol Biol Phys, 118: 2024,1435-1444


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