Katherine L. Nathanson, MD

Medical Genetics
Accepting new patients
Sees patients age 4 to 65
Penn Translational Medicine and Human Genetics
Penn Medicine Provider

About me

  • Deputy Director, Abramson Cancer Center
  • Pearl Basser Professor for BRCA-Related Research at the Abramson Cancer Center of the University of Pennsylvania
  • Professor of Medicine in Genetics

My education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: Beth Israel Deaconess Medical Center
  • Fellowship: Children's Hospital of Philadelphia

Spoken languages

English
English

Reviews

Average Rating

59 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
June 2026
friendly
Anonymous
March 2026
she was extremely knowledgeable/professional yet personable and comforting as well. checks all the boxes!
Anonymous
January 2026
very knowledgeable
Anonymous
December 2025
very informative

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Dr. Nathanson is a Penn Medicine physician.

Qualifications and experience

Treatments and conditions

Research

Publications

Abbasi AA, Lustig RA, Dorsey JF, Grady SM, Lee JYK, Kurtz GA, Shabason JE, Cengel KA, Bigelow DC, Brant JA, Ruckenstein MJ, Rassekh CH, Nathanson KL, Raper A, Huan Y, Alonso-Basanta M. Treatment Outcomes of Radiation Therapy of Paragangliomas of the Head and Neck at a Single Institution , Int J Part Ther, 21: 2026


Dalwadi S, Engelhardt NM, Muraresku CC, Keith K, Valverde KD, Nathanson KL, Falk MJ Cancer prevalence in primary mitochondrial disease patients and their families , Ther Adv Rare Dis, 7(26330040261471914): 2026


Reiss KA, Xia M, Akamandisa M, D'Andrea K, Wubbenhorst B, Lord CJ, Pettitt SJ, Tutt ANJ, Brown TJ, O'Hara MH, Schneider C, Teitelbaum U, Hannan Z, Hood R, Tondon R, Vonderheide RH, Domchek SM, Nathanson KL Long-Term Outcomes of Patients With BRCA+ or PALB2+ Pancreatic Cancer Treated With Maintenance Rucaparib: A Secondary Analysis of a Nonrandomized Clinical Trial , JAMA Oncol, 12(6): 2026,666-670


Ping J, Jia G, Cai Q, Guo X, Wang J, Tao R, Li B, Bauer JA, Xie Y, Ambs S, Barnard ME, Chen Y, Choi JY, Gao YT, Garcia-Closas M, Gu J, Hu JJ, Iwasaki M, John EM, Kweon SS, Li CI, Matsuda K, Matsuo K, Nathanson KL, Nemesure B, Olopade OI, Pal T, Park SK, Park B, Press MF, Sanderson M, Sandler DP, Yao S, Zheng Y, Ahearn T, Brewster AM, Falusi A, Hennis AJM, Ito H, Kubo M, Lee ES, Makumbi T, Mapoko BSE, Noh DY, O'Brien KM, Ojengbede O, Olshan AF, Park MH, Reid S, Yamaji T, Zirpoli G, Butler EN, Huang M, Low SK, Obafunwa J, Weinberg CR, Zhang H, Zhao H, Ambrosone CB, Cote ML, Huo D, Haiman CA, Kang D, Palmer JR, Troester MA, Shu XO, Long J, Zheng W Multi-ancestry transcriptome-wide association studies uncover insights into breast cancer genetics and biology , Nat Commun, 17(1)(7025): 2026


Akamandisa MP, Xia M, Cheah W, Wubbenhorst B, D'Andrea KP, Fan M, Shilan JS, Pueschl D, Nayak A, McKenzie H, Tapper W, Copson ER, Cutress RI, Domchek SM, Eccles DM, Nathanson KL Comparative analysis of distinct genomic landscapes in young-onset gBRCA1/2 breast cancer , JCI Insight, 11(12)(e203005): 2026


Akamandisa MP, Xia M, Cheah W, Wubbenhorst B, D'Andrea KP, Fan M, Shilan JS, Pueschl D, Nayak A, McKenzie H, Tapper W, Copson ER, Cutress RI, Domchek SM, Eccles DM, Nathanson KL Comparative analysis of distinct genomic landscapes in young-onset gBRCA1/2 breast cancer , JCI Insight, 11(12)(e203005): 2026


Safonov A, Lee M, Brown DN, Boscolo Bielo L, Mehine M, Bandlamudi C, O'Leary B, Shao H, Vicente L, Muldoon D, Zhu A, Ros S, Marra A, Selenica P, Bieche I, Wubbenhorst B, Ferraro E, Courtois L, El Botty R, Ahmed M, Moiso E, An JA, Donoghue MTA, Will M, Pareja F, Nizialek E, Lukashchuk N, Sofianopoulou E, Liu Y, Huang X, Chappey C, Staniszewska AD, Ross D, Mandelker D, Ladanyi M, Schultz N, Berger MF, Scaltriti M, Reis-Filho JS, Li BT, Offit K, Norton L, Shen R, Maxwell KN, Couch F, Domchek SM, Marangoni E, Shah S, Albertella MR, Serra V, Weigelt B, Solit DB, Nathanson KL, Robson ME, Turner NC, Chandarlapaty S, Razavi P Homologous recombination deficiency and hemizygosity drive resistance in breast cancer , Nature, 652(8110): 2026,752-762


Li JL, Zhang H, Wang X, Jia G, McClellan JC, Guo W, Sun Y, Fiorica PN, Ambs S, Barnard ME, Chen Y, Garcia-Closas M, Gu J, Hu JJ, John EM, Nathanson KL, Nemesure B, Pal T, Shu XO, Press MF, Sanderson M, Sandler DP, Troester MA, Yao S, Long J, Ahearn TU, Brewster AM, Falusi A, Kraft P, Hennis AJM, Makumbi T, Mapoko BSE, O'Brien KM, Ojengbede O, Olshan AF, Reid S, Zirpoli G, Cai Q, Butler EN, Huang M, Obafunwa J, Weinberg CR, Ambrosone C, Ping J, Tao R, Li B, Guo X, Gao G, Conti DV, Chatterjee N, Palmer JR, Olopade OI, Zheng W, Haiman CA, Huo D Improved polygenic risk prediction models for breast cancer subtypes in women of African ancestry , Nat Genet, 58(3): 2026,560-569


Godbole AR, Wood E, Egleston B, Hoffman-Andrews L, Brown S, Howe S, Shastri S, Mim R, Feng J, Owens A, Domchek S, Pyeritz R, Katona BW, Kallish S, Sirugo G, Weaver J, Fleisher L, Wen KY, Elkin E, Nathanson KL, Rader DJ, Bradbury AR A randomized study of digital versus genetic counselor return of actionable genetic research results to biobank participants (RESPECT3 study) , BMC Med Ethics, 27(1)(122): 2026


Choi S, Rocca MS, Vinanzi C, Pluta J, Kuzbari Z, Loveday C, Allen S, Torr B, Weathers B, Anson-Cartwright L, Feldman DR, Gietema JA, Gonzalez-Neira A, Hamilton RJ, Krausz C, Moirano G, Nead KT, Nsengimana J, Poynter JN, Vaughn DJ, Kanetsky PA, Nathanson KL, Ferlin A, Turnbull C, Rowlands CF Association of Y-chromosomal gr/gr deletions with testicular germ cell tumor: whole-genome analysis of 198,306 individuals , medRxiv [Preprint]: 2026