Neonatology and Newborn Services
Karen Marie Puopolo, MD, PhD
she/her/hers
Independent provider
Accepting new patients
Sees newborns through age 1 month
Neonatology and Newborn Services Pennsylvania Hospital

About me

  • Chief, Section on Newborn Medicine, Pennsylvania Hospital
  • Professor of Pediatrics (Neonatology & Newborn Services) at the Children's Hospital of Philadelphia

Education and training

  • Medical School: Tufts University School of Medicine
  • Residency: Children's Hospital of Boston
  • Fellowship: Children's Hospital of Boston

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
Dr. Puopolo is an independent physician who is not employed by Penn Medicine.

Qualifications and experience

Treatments and Conditions

My research

Shankaran S, Laptook AR, Guimaraes C, et al. for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network Human Development Neonatal Research Network. NICHD Magnetic Resonance Brain Imaging Score in Term Infants With Hypoxic-Ischemic Encephalopathy: A Secondary Analysis of a Randomized Clinical Trial , JAMA Pediatr., 179(4): 2025


Walter J, Hill DL, Cetin A, DeWitt A, Kellom K, Quarshie W, Griffis H, Shults J, Arnold R, Tjia J, Puopolo K, Curley MAQ, Feudtner C. A Pediatric Interprofessional Cardiac Intensive Care Unit Intervention: CICU Teams and Loved Ones Communicating (CICU TALC) is Feasible, Acceptable, and Improves Clinician Communication Behaviors in Family Meetings. , Pediatr Cardiol, 46(4): 2025


Coggins SA, Wade KC, Watt KM, Downes KJ, Puopolo KM. Vancomycin Concentrations in Umbilical Cord Blood After Intrapartum Exposure , Obstet Gynecol, 145(4): 2025,435-438


Coggins SA, Triebwasser JE, Puopolo KM. Diagnostic evaluation to identify infection-attributable stillbirth , J Perinatol: 2025


Mukhopadhyay S, Puopolo KM Perinatal and Neonatal Infections: Core Concepts, Emerging Issues, and Future Perspectives , Clin Perinatol, 52(1): 2025,xix-xxii


Medoro AK, Puopolo KM Transplacental Antibodies: Role of Maternal Vaccines and Immunity , Clin Perinatol, 52(1): 2025,101-113


Chawla S, Wyckoff MH, Lakshminrusimha S, et al; National Institute of Child Health and Human Development (NICHD) Neonatal Research Network (NRN) Short Duration of Antenatal Corticosteroid Exposure and Outcomes in Extremely Preterm Infants , JAMA Netw Open, 8(1): 2025,e2461312


Coggins SA, Puopolo KM. Intrapartum antibiotic prophylaxis for group B Streptococcus: what exactly is adequate? , Arch Dis Child Fetal Neonatal Ed, 110(2): 2025


Mukhopadhyay S, Kaufman DA, Saha S, Puopolo KM, Flannery DD, Weimer KED, Greenberg RG, Sanchez PJ, Eichenwald EC, Cotten CM, Stoll BJ, Laptook A. Late-Onset Sepsis Among Extremely Preterm Infants During the COVID-19 Pandemic , Pediatrics, 155(2): 2025,e2024067675


May MF, McKinney ML, Cestare D, Hussey A, Zevallos AB, Garber S, Posencheg MA, Puopolo KM, Mukhopadhyay S. Improving Time to First Feeding for Preterm Infants: A Quality Improvement Approach , Pediatr Qual Saf, 10(2): 2025,e798


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