Karen Marie Puopolo, MD, PhD
she/her/hers
Neonatology and Newborn Services
Independent provider
Accepting new patients
Sees newborns through age 1 month
Neonatology and Newborn Services Pennsylvania Hospital
About me
- Chief, Section on Newborn Medicine, Pennsylvania Hospital
- Professor of Pediatrics (Neonatology & Newborn Services) at the Children's Hospital of Philadelphia
My education and training
- Tufts University School of MedicineMedical School
- Boston Children's HospitalResidency
- Boston Children's HospitalFellowship
Spoken languages
English
English
Insurance accepted
Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.
Locations
Penn Medicine hospital privileges
- Pennsylvania Hospital: Has privileges to treat patients in the hospital.
Dr. Puopolo is an independent physician who is not employed by Penn Medicine.
Qualifications and experience
- Neonatal-Perinatal Medicine, 2003
- American Academy of Pediatrics, National
- American Pediatric Society, National
- Center for Pediatric Clinical Excellence (now Clinical Futures), Local
- Centers for Disease Control and Prevention and Vermont-Oxford Network, National
- Centers for Disease Control and Prevention, National
- Massachusetts Medical Society, Local
- Pediatric Academic Society Annual Meeting Scientific Abstract Reviewer, National
- Pediatric Infectious Disease Society, National
- Pennsylvania Perinatal Quality Collaborative, Local
- Philadelphia Department of Public Health, Local
- Society for Pediatric Research, National
Treatments and conditions
Research
Publications
Tesini BL, Caserta MT, Park AH, Puopolo KM, Reilly BK, Kuo DZ, Lehmann CU; Committee on Infectious Diseases; Section on Otolaryngology–Head and Neck Surgery; Committee on Fetus and Newborn; Council on Children With Disabilities Care of the Infant With Congenital Cytomegalovirus Infection: Clinical Report , Pediatrics: 2026,e2026078595
Coggins SA, Puopolo KM Antibiotic Therapy for the Prevention and Treatment of Neonatal Sepsis , Clin Perinatol, 53(3): 2026,653-675
Coggins SA, Flannery DD, Mukhopadhyay S, Puopolo KM. Parental Decline of Newborn Vitamin K and Hepatitis B Vaccine Administration by Newborn Sex , JAMA Netw Open, 9(6): 2026,e2618410
Flannery DD, Feng J, Zevallos Barboza A, Potter RF, Puopolo KM, Mutalik V, Weissman SJ, Dudley EG Clonally related Escherichia coli ST69 causing neonatal sepsis in preterm siblings born 1 year apart , ASM Case Rep, 2(4): 2026,e00221-25
May MF, Zevallos Barboza A, Garber SJ, Puopolo KM, Mukhopadhyay S, Flannery DD Long-term sustainability and safety of a delivery-based early-onset sepsis evaluation strategy for very low birth weight infants , J Perinatol, 46(5): 2026,865-867
Proaño A, Green M, Zevallos Barboza A, Greenberg RG, Puopolo KM, Flannery DD Anti-cytomegalovirus medications among very low birth weight infants in the United States from 2016 to 2023 , J Perinatol, 46(5): 2026,748-753
Minor AA, Coggins SA, Sheffield JS, Puopolo KM, Milstone AM. A model for prevention: applying lessons from Group B Streptococcus to Staphylococcus aureus in very low birth weight neonates , J Perinatol, 46(5): 2026,689-691
Yerram PS, Rosewood H, Kuzniewicz MW, Gerber JS, Puopolo KM, Szymczak JE, Schamtz M, Bonafide C, Brent CR, Christ L, Noh E, Muhumuza CK, Ivashchuk A, Bass C, Bress J, Dhudasia MB, Garber S, Mukhopadhyay S. Barriers and Facilitators for Vancomycin Reduction in Preterm Infants: A Survey of Neonatal Clinicians , Pediatric Academic Societies: 2026
Flannery DD, Zevallos A, Mukhopadhyay S, Coggins SA, Li Y, Gerber JS, Weissman SJ, Puopolo KM National Trends in Escherichia coli Antibiotic Susceptibility in Neonatal Early-Onset Sepsis, 2009-2023 , Pediatric Academic Societies: 2026
Zepeda F, Pulsifer A, Puopolo KM, Wade KC, Gabbert ML, Iannocone J, Hallman K, Anca R, Wheeler MN, Mukhopadhyay S Redefining Normal: Impact of Revised Glucose Thresholds on Neonatal Hypoglycemia , Pediatric Academic Societies: 2026