John T. Seykora, MD, PhD

Accepting new patients
Sees patients age 18 and up
Headshot of John T. Seykora, MD, PhD
Penn Medicine Provider

About me

  • Professor of Dermatology

Dr. Seykora reads dermatopathology at HUP, but does not schedule appointments with patients.

My education and training

  • Medical School: NewYork-Presbyterian / Weill Cornell Medical Center
  • Residency: University of Pennsylvania Health System
  • Fellowship: University of Pennsylvania Health System

Spoken languages

English
English

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Seykora is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

Research

Publications

Freeburg N F, Chafamo D, Gopikrishna GK, Murphy, RM, Peng, JJ, Parthasarathy, S, Dumont, D, Estrada, EE, Logun, MT, Sun Y, Wang X, Grover P, Rodriguez JL, Zhang DL, Park K, Fu Y, Hamouda NB, Hernandez-Verdi I, Lamrani L, Hicks KA, Cooper NA, Ekwebara C, Bawden EG, Waterfall JJ, Fuentealba J, Alcantra M, Seykora JT, Prouty SM, Barrett D, Banerjee E, Cox A, Assenmacher CA, Macia C, Yin M, Carpenter EL, Ming GL, Sautes-Fridman C, Fridman WH, Tartour E, Wherry EJ, Amigorena S, Fraietta JA, Nasrallah MP, Song H, Miller TE, Bagley SJ, O’Rourke DM, Binder ZA, Alanio C and Silverbush D The critical role of the endogenous immune compartment after CAR T cell therapy in recurrent GBM , Cell: 2026


Kuprasertkul N, Moore AF, D'souza CA, Chini J, Ko EK, Huang S, Zhang S, Anderson AS, Egolf S, Pinheiro LV, Jaccard A, Magahis CT, Bao L, Aubert Y, Olingou CR, Prouty SM, Brennan-Crispi D, Hill DA, Seykora JT, Wellen KE, Capell BC Inhibiting LSD1 unlocks retinoid AP-1 programming to activate epithelial immunity and skin tumor suppression , J Clin Invest: 2026


Natale CA, Mercado S, Zhuang R, Aguirre-Portolés C, Olayide I, Arnatt CK, Seykora JT, Garyantes TK, Luke W, Ridky TW. An enantiomerically pure agonist of the G protein-coupled estrogen receptor suitable for clinical development. , Cancer Res Commun. : 2025


Zhu X, Xu M, Portal C, Lin Y, Ferdinand A, Peng T, Morrisey EE, Dlugosz AA, Castellano JM, Lee V, Seykora JT, Wong SY, Iomini C, Millar SE. Identification of Meibomian gland stem cell populations and mechanisms of aging. , Nat Commun.: 2025


Nguyen PTT, Shiue M, Kuprasertkul N, Costa-Pinheiro P, Izzo LT, Pinheiro LV, Affronti HA, Gugiu G, Ghaisas S, Liu JY, Harris JC, Bradley CW, Seykora JT, Yang X, Kambayashi T, Mesaros C, Capell BC, Wellen KE. Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis. , Cell Rep.: 2025


Hoffman CL, Bharathan NK, Shibata Y, Giang W, Gudjonsson JE, Seykora JT, Prouty SM, Stahley SN, Payne AS, Kowalczyk AP. Pemphigus Vulgaris Autoantibodies Induce an Endoplasmic Reticulum Stress Response. , J Invest Dermatol.: 2025


Yu H, Nagi SS, Usoskin D, Hu Y, Kupari J, Bouchatta O, Yan H, Cranfill SL, Gautam M, Su Y, Lu Y, Wymer J, Glanz M, Albrecht P, Song H, Ming GL, Prouty S, Seykora J, Wu H, Ma M, Marshall A, Rice FL, Li M, Olausson H, Ernfors P, Luo W Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation , Nat Neurosci: 2024


Grice EA, Brennan-Crispi D, Rodriguez N, Margolis DJ, Seykora JT, Cotsarelis G, Taylor SC, Shuda J. Penn Academy for Skin Health (PASH): An Experiential Pipeline Program in Skin Biology and Dermatology for High-School Students. , J Invest Dermatol.: 2024


Abbott JJ, Jiang AJ, Godse R, Ahmed S, Senft SC, Wilson MA, Cohen JV, Mitchell TC, Ogunleye TA, Higgins HW 2nd, Shin TM, Miller CJ, Roth JJ, Priore SF, Castelo-Soccio L, Elenitsas R, Seykora JT, Nathanson KL, Chu EY Inherited Basaloid Neoplasms Associated With SUFU Pathogenic Variants , JAMA Dermatol. : 2024


Sati S, Huang J, Kersh AE, Jones P, Ahart O, Murphy C, Prouty SM, Hedberg ML, Jain V, Gregory SG, Leung DH, Seykora JT, Rosenbach M, Leung TH Recruitment of CXCR4+ type 1 innate lymphoid cells distinguishes sarcoidosis from other skin granulomatous diseases , J Clin Invest.: 2024


View all publications