Penn Medicine Provider
Renal Electrolyte and Hypertension
John Demko, MD
Accepting new patients
Sees patients age 18 and up
Penn Renal Electrolyte and Hypertension Perelman
View 2 additional locations

About me

  • Assistant Professor of Clinical Medicine (Renal-Electrolyte and Hypertension)

Education and training

  • Medical School: University of Pittsburgh
  • Residency: UCSF Medical Center and Hospital
  • Fellowship: UCSF Medical Center and Hospital

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Dr. Demko is a Penn Medicine physician.

Qualifications and experience

My research

Demko JE, Saha B, Takagi E, Weber R, Pearce D A Novel Function of FOXO4 and mTORC2 for Regulation of Renal Gluconeogenesis , Poster Presentation, American Society of Nephrology Kidney Week, San Diego, CA.: 2024


Judson TJ, Lo L, Demko JE, Mourad M, Liu KD, Wachter RM, Lopez I, Tummalapalli SL. Addressing Inpatient Hyponatremia Through Targeted Automatic E-consults: A Pilot Randomized Trial , J Gen Intern Med: 2024


Demko J, Weber R, Pearce D, Saha B. Aldosterone-independent regulation of K + secretion in the distal nephron , Curr Opin Nephrol Hypertens, 33(5): 2024,526-534


Demko J, Saha B, Takagi E, Mannis A, Weber R, Pearce D. Coordinated Regulation of Renal Glucose Reabsorption and Gluconeogenesis by mTORC2 and Potassium , bioRxiv: 2024


Demko JE, Saha B, Takagi E, Manis A, Pearce D High Potassium Suppresses Glycosuria in Tubule- specific mTORC2 Knockout Mice , Poster Presentation, American Society of Nephrology Kidney Week, Philadelphia, PA.: 2023


Saha B, Shabbir W, Takagi E, Duan XP, Leite Dellova DCA, Demko J, Manis A, Loffing-Cueni D, Loffing J, Sørensen MV, Wang WH, Pearce D. Potassium Activates mTORC2-dependent SGK1 Phosphorylation to Stimulate Epithelial Sodium Channel: Role in Rapid Renal Responses to Dietary Potassium , J Am Soc Nephrol, 34(6): 2023,1019-1038


Saha B, Leite-Dellova DCA, Demko J, Sørensen MV, Takagi E, Gleason CE, Shabbir W, Pearce D. WNK1 is a chloride-stimulated scaffold that regulates mTORC2 activity and ion transport , J Cell Sci, 135(23): 2022,260313


Demko JE, Saha B, Takagi E, Manis A, Richman P, Pearce D Renal Tubule-Specific mTORC2 Deletion Increases Gluconeogenesis and Causes Glycosuria , Poster Presentation, American Society of Nephrology Kidney Week, Orlando, FL: 2022


Saha B, Deise C, Takagi E, Demko J, Shabbir W, Pearce D WNK1 is a Chloride-sensing Scaffold that Potentially Regulates mTORC2 Activity and ENaC , Poster Presentation, American Society of Nephrology Kidney Week, Orlando, FL.: 2022


Shabbir W, Demko JE, Takagi E, Saha B, Leite-Dellova DC, Sambandam B, Pearce D mTORC2 Is Essential for Sodium-Glucose Cotransporter , Poster Presentation, American Society of Nephrology Kidney Week (Virtual): 2021