John Demko, MD
Renal Electrolyte and Hypertension
Headshot of John Demko, MD

John Demko, MD

Renal Electrolyte and Hypertension
Accepting new patients
Sees patients age 18 and up
Penn Renal Electrolyte and Hypertension Perelman
View 1 additional location
Headshot of John Demko, MD
Penn Medicine Provider

About me

  • Assistant Professor of Clinical Medicine (Renal-Electrolyte and Hypertension)

My education and training

  • University of PittsburghMedical School
  • University of California San FranciscoResidency
  • University of California San FranciscoFellowship

Spoken languages

English
English

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Demko is a Penn Medicine physician.

Qualifications and experience

Treatments and conditions

Research

Publications

Demko J, Saha B, Takagi E, Manis A, Weber R, Koepsell H, Pearce D Coordinated Regulation of Renal Glucose Reabsorption and Gluconeogenesis by mTORC2 and Potassium , Journal of the American Society of Nephrology: 2025


Demko JE, Saha B, Takagi E, Weber R, Pearce D A Novel Function of FOXO4 and mTORC2 for Regulation of Renal Gluconeogenesis , Poster Presentation, American Society of Nephrology Kidney Week, San Diego, CA.: 2024


Judson TJ, Lo L, Demko JE, Mourad M, Liu KD, Wachter RM, Lopez I, Tummalapalli SL. Addressing Inpatient Hyponatremia Through Targeted Automatic E-consults: A Pilot Randomized Trial , J Gen Intern Med: 2024


Demko J, Weber R, Pearce D, Saha B. Aldosterone-independent regulation of K + secretion in the distal nephron , Curr Opin Nephrol Hypertens, 33(5): 2024,526-534


Demko J, Saha B, Takagi E, Mannis A, Weber R, Pearce D. Coordinated Regulation of Renal Glucose Reabsorption and Gluconeogenesis by mTORC2 and Potassium , bioRxiv: 2024


Demko JE, Saha B, Takagi E, Manis A, Pearce D High Potassium Suppresses Glycosuria in Tubule- specific mTORC2 Knockout Mice , Poster Presentation, American Society of Nephrology Kidney Week, Philadelphia, PA.: 2023


Saha B, Shabbir W, Takagi E, Duan XP, Leite Dellova DCA, Demko J, Manis A, Loffing-Cueni D, Loffing J, Sørensen MV, Wang WH, Pearce D. Potassium Activates mTORC2-dependent SGK1 Phosphorylation to Stimulate Epithelial Sodium Channel: Role in Rapid Renal Responses to Dietary Potassium , J Am Soc Nephrol, 34(6): 2023,1019-1038


Saha B, Leite-Dellova DCA, Demko J, Sørensen MV, Takagi E, Gleason CE, Shabbir W, Pearce D. WNK1 is a chloride-stimulated scaffold that regulates mTORC2 activity and ion transport , J Cell Sci, 135(23): 2022,260313


Saha B, Deise C, Takagi E, Demko J, Shabbir W, Pearce D WNK1 is a Chloride-sensing Scaffold that Potentially Regulates mTORC2 Activity and ENaC , Poster Presentation, American Society of Nephrology Kidney Week, Orlando, FL.: 2022


Demko JE, Saha B, Takagi E, Manis A, Richman P, Pearce D Renal Tubule-Specific mTORC2 Deletion Increases Gluconeogenesis and Causes Glycosuria , Poster Presentation, American Society of Nephrology Kidney Week, Orlando, FL: 2022