Jay Fitzgerald Dorsey, MD, PhD
Radiation Oncology
Accepting new patients
Sees patients age 18 and up
Penn Radiation Oncology Perelman-Concourse Level
Headshot of Jay Fitzgerald Dorsey, MD, PhD
Penn Medicine Provider

About me

  • Associate Professor of Radiation Oncology

Education and training

  • Medical School: University of South Florida
  • Residency: University of South Florida
  • Residency: University of Pennsylvania Health System

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Chester County Hospital: Has privileges to treat patients in the hospital.
Dr. Dorsey is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Messing I, Linkowski L, Riina MD, Berger M, Baron J, Wang X, Kallan M, Hubbeling HG, Lustig RA, Dorsey JF, Kurtz G, Nagda S, Lukens JN, Flowers A, Lee JYK, Amankulor NM, Jackson C, Mohan S, Amaravadi RK, Schuchter LM, Huang AC, Mitchell TC, Alonso-Basanta M, Lebow ES Outcomes after SRS and ipilimumab plus nivolumab for melanoma brain metastases following prior immune checkpoint inhibitor or targeted therapy , Oncologist, 31(4): 2026


Ni H, Reitman ZJ, Zou W, Akhtar MN, Paul R, Huang M, Zhang D, Zheng H, Zhang, R, Ma R, Ngo G, Zhang L, Diffenderfer ES, Motlagh SAO, Kim MM, Minn AJ, Dorsey JF, Foster JB, Metz J, Koumenis C, Kirsch DG, Gong Y, Fan Y FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy , Nat Cancer, 6(3): 2025


Dastgheyb SS, Dreyfuss AD, LaRiviere MJ, Mohiuddin JJ, Baumann BC, Shabason J, Lustig RA, Dorsey JF, Lin A, Grady SM, O'Malley BW, Lee JYK, Newman JG, Schuster JM, Alonso-Basanta M. A Prospective Phase I/II Clinical Trial of High-Dose Proton Therapy for Chordomas and Chondrosarcomas , Adv Radiat Oncol, 9: 2024,101456


Zhang D, Cleveland AH, Krimitza E, Han K, Yi C, Stout AL, Zou W, Dorsey JF, Gong Y, Fan Y. Spatial analysis of tissue immunity and vascularity by light sheet fluorescence microscopy , Nat Protoc: 2024


Yang F, Akhtar MN, Zhang D, El-Mayta R, Shin J, Dorsey JF, Zhang L, Xu X, Guo W, Bagley SJ, Fuchs SY, Koumenis C, Lathia JD, Mitchell MJ, Gong Y, Fan Y. An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma , Sci Adv: 2024


Dong YC, Nieves LM, Hsu JC, Kumar A, Bouché M, Krishnan U, Mossburg KJ, Saxena D, Uman S, Kambayashi T, Burdick JA, Kim MM, Dorsey JF, Cormode DP Novel Combination Treatment for Melanoma: FLASH Radiotherapy and Immunotherapy Delivered by a Radiopaque and Radiation Responsive Hydrogel , Chem Mater, 35(22): 2023


Paul R, Dorsey JF, Fan Y Cell plasticity, senescence, and quiescence in cancer stem cells: Biological and therapeutic implications , Pharmacol Ther.: 2022


Yang AI, Mensah-Brown KG, Shekhtman EF, Kvint S, Wathen CA, Hitti FL, Alonso-Basanta M, Avery SM, Dorsey JF, Y K Lee J. Gamma Knife radiosurgery for trigeminal neuralgia provides greater pain relief at higher dose rates , J Radiosurg SBRT: 2022


Lee SH, Kao GD, Feigenberg SJ, Dorsey JF, Frick MA, Jean-Baptiste S, Uche CZ, Cengel KA, Levin WP, Berman AT, Aggarwal C, Fan Y, Xiao Y Multiblock Discriminant Analysis of Integrative <sup>18</sup>F-FDG-PET/CT Radiomics for Predicting Circulating Tumor Cells in Early-Stage Non-small Cell Lung Cancer Treated With Stereotactic Body Radiation Therapy , Int J Radiat Oncol Biol Phys., 110(5): 2021,1451-1465


Mathilde Bouché, Yuxi C Dong, Saad Sheikh, Kimberly Taing, Deeksha Saxena, Jessica C Hsu, Minna H Chen, Ryan D Salinas, Hongjun Song, Jason A Burdick, Jay Dorsey, David P Cormode Novel Treatment for Glioblastoma Delivered by a Radiation Responsive and Radiopaque Hydrogel , ACS Biomater Sci Eng.: 2021


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