He Nucleus Xu, PhD
Penn Medicine Provider

About me

  • Research Assistant Professor of Radiology

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My research

Irene Georgakoudi, Melissa C. Skala, Kyle P. Quinn, Chiara Stringari, Janet E. Sorrells, Ahmed A. Heikal, Lin Z. Li, He N. Xu, Sixian You, Alex J. Walsh, Rupsa Datta, Kayvan Samimi, Amani A. Gillette, Kevin W. Eliceiri, Mihaela Balu, Stephen A. Boppart, Michelle A. Digman, Kylie R. Dunning, Conor L. Evans, Alba Alfonso Garcia, Jessica P. Houston, Wonsang Hwang, Matthew M. Lindley, Xingde Li, Zhiyi Liu, Laura Marcu, Sangeeta Murugkar, Michael G. Nichols, Raluca Niesner, Sapun H. Parekh, Narasimhan Rajaram, Suman Ranjit, Keyue Shen, Lingyan Shi, Belén Torrado, Alexander Vallmitjana, Michael Wang-Evers, Roger Zemp Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling , J. Biomed. Opt., 30(S2): 2025,S23901


Kollmar, J.; Xu, J.; Gonzalves, D.; Baur, J.A.; Li, L.Z.; Tchou, J.; Xu, H.N.* Differential Mitochondrial Redox Responses to the Inhibition of NAD+ Salvage Pathway of Triple Negative Breast Cancer Cells , Cancers, 17(1): 2024,7


Xu HN*^, Gonzalves D, Hoffman JH, Baur JA, Li LZ, Jensen EA^ Use of Optical Redox Imaging to Quantify Alveolar Macrophage Redox State in Infants: Proof of Concept Experiments in a Murine Model and Human Tracheal Aspirates Samples , Antioxidants , 13(5): 2024,546


Xu, H.N.*; Gourmaud, S.; Podsednik, A.; Li, X.; Zhao, H.; Jensen, F.E.; Talos, D.M.*; Li, L.Z.* Optical redox imaging of ex vivo hippocampal tissue reveals age-dependent alterations in the 5xFAD mouse model of Alzheimer’s disease , Metabolites, 12: 2022,786


Xu, H. N., Lin, Z., Gandhi, C. K., Amatya, S., Wang, Y., Li, L. Z. and Floros, J. Sex and SP-A2 dependent NAD(H) Redox Alterations in Mouse Alveolar Macrophages in Response to Ozone Exposure: Potential Implications for COVID-19 , Antioxidants, 9(10): 2020,915


He N. Xu*, Huaqing Zhao, Karthikeyani Chellappa, James G. Davis, Shoko Nioka, Joseph A. Baur, Lin Z. Li* Optical redox imaging of fixed unstained muscle slides reveals useful biological information , Mol Imaging Biol, 21(3): 2019,417-425


Allison Podsednik, Annemarie Jacob, Lin Z. Li, He N. Xu* Relationship between optical redox status and reactive oxygen species in cancer cells , React Oxyg Species, 9(26): 2020,95-108


Xu, He N.*, Tchou, Julia., Feng, Min, Zhao, Huaqing, Li, Lin Z*. Optical redox imaging indices discriminate human breast cancer from normal tissues , J Biomed Opt, 21: 2016,114003


Xu, He N., Nioka, Shoko, Glickson, Jerry D., Chance, Britton, Li, Lin Z. Quantitative mitochondrial redox imaging of breast cancer metastatic potential , J Biomed Opt, 15(3): 2010,036010


Li, L. Z., Zhou, R., Xu, H. N., Moon, L., Zhong, T., Kim, E. J., Qiao, H., Reddy, R., Leeper, D., Chance, B., Glickson, J. D. Quantitative magnetic resonance and optical imaging biomarkers of melanoma metastatic potential , Proc Natl Acad Sci USA, 106(16): 2009,6608-13