Gustavo S. Guandalini, MD

Cardiology
Accepting new patients
Sees patients age 18 and up
Penn Heart and Vascular Center
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Make an appointmentCall 215-615-4949
Headshot of Gustavo S. Guandalini, MD
Penn Medicine Provider

About me

  • Assistant Professor of Clinical Medicine (Cardiovascular Medicine)

I am originally from Curitiba, Brazil, where I earned my medical degree in 2007 from the Federal University of Paraná, the oldest University in the country. After practicing a few years as a Family Physician in my hometown, I moved to the United States in 2009 to work as a post-doctoral research fellow in Biophysics at the Armed Forces Institute of Pathology, in Washington, D.C. I then completed my Internal Medicine residency, followed by a year as a Chief Resident, at the Georgetown University Hospital/Washington Hospital Center program, the largest hospital in our nation's capital. My Cardiology fellowship was then completed in New York, at NYU School of Medicine. Since 2018, I have been at Penn Medicine, where I received my training in cardiac electrophysiology and stayed as an attending physician treating patients with cardiac rhythm disorders.

My education and training

  • Medical School: Universidade Federal do Parana
  • Residency: Medstar Health/Georgetown-Washington Hospital Program
  • Fellowship: NYU Langone Medical Center
  • Fellowship: University of Pennsylvania Health System

Reviews

Average Rating

362 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
April 2026
compassion and empathy are beyond reproach
Anonymous
March 2026
great communication
Anonymous
March 2026
very knowledgable
Anonymous
February 2026
dr. Guandalini is an outstanding physician who truly cares about his patients, even to the extent that he follows up after hours with personal phone calls. in my case, he has always taken the time during office visits to go over relevant details on procedures thoroughly and answering my questions.

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
Dr. Guandalini is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

Research

Publications

Tan JL, Chirinos J, Patel D, Jagasia D, Hyman MC, Guandalini GS, Nazarian S, Lin D, Supple G, Frankel DS, Callans DJ, Marchlinski FE, Ren JF, Markman TM. Intracardiac echocardiography for left ventricular diastolic function assessment during atrial fibrillation ablation. Intracardiac echocardiography for left ventricular diastolic function assessment during atrial fibrillation ablation. , Journal of Interventional Cardiac Electrophysiology, 69(1): 2026,53-62

Oraii A, Afzalian A, Chaumont C, Rodriguez-Queralto O, Liao TE, Gad MM, Zaidi SMM, Zado E, Tschabrunn CM, Hanumanthu BKJ, Hyman MC, Markman TM, Guandalini G, Kumareswaran R, Deo R, Riley MP, Lin D, Garcia FC, Nazarian S, Supple GE, Schaller RD, Frankel DS, Callans DJ, Dixit S, Marchlinski FE. Role of non-pulmonary vein triggers in outcomes of first-time atrial fibrillation ablation. , JACC: Clinical Electrophysiology, 12(5): 2026,1037-1047

Boyle TA, Callans DC, Deo R, Dixit S, Enriquez A, Epstein AE, Garcia F, Guandalini G, Hanumanthu BK, Hyman MC, Kumareswaran R, Lin D, Marchlinski FE, Markman TM, Mirwais M, Nazarian S, Riley M, See V, Shivamurthy P, Supple GE, Schaller R, Frankel DS. Quantitative vector screening to improve sensing and reduce inappropriate shocks with the subcutaneous implantable cardioverter-defibrillator. , Circulation: Arrhythmia and Electrophysiology, 19(5): 2026,e014581

Guandalini GS Combined endocardial radiofrequency and pulsed-field left ventricular summit ablation: With great power comes great responsibility. , JACC: Case Reports, 30(41): 2025,1-2

Enriquez A, Yogasundaram H, Neira V, Guandalini G, Markman T, Shivamurty P, Hyman M, Hanumanthu BK, Lin D, Schaller R, Supple G, Dixit S, Deo R, Nazarian S, Kumareswaram R, Riley M, Epstein A, Zado E, Callans D, Frankel D, Marchlinski F, Garcia F. Stepwise anatomical approach to ablation of intramural outflow tract ventricular arrhythmias guided by septal coronary venous mapping. , Circulation, 152(3): 2025,163-171

Raad M, Oranefo J, Yogasundaram H, Gurin MI, Zado E, Walsh M, Markman T, Guandalini G, Hyman MC, Schaller R, Kumareswaran R, Supple G, Deo R, Nazarian S, Riley M, Lin D, Garcia F, Frankel DS, Callans D, Epstein AE, Marchlinski FE, Dixit S. Temporary restoration of sinus rhythm improves outcomes of catheter ablation for longstanding persistent atrial fibrillation. , Journal of Cardiac Electrophysiology, 36(8): 2025,1966-1972

Oraii A, Chaumont C, Rodriguez-Queralto O, Wasiak M, Thind M, Peters CJ, Zado E, Hanumanthu BKJ, Markman TM, Hyman MC, Tschabrunn CM, Guandalini G, Enriquez A, Shivamurthy P, Kumareswaran R, Riley MP, Lin D, Schaller RD, Nazarian S, Callans DJ, Supple GE, Garcia FC, Frankel DS, Dixit S, Marchlinski FE. Preprocedural screening tool to guide nonpulmonary vein trigger testing in first-time atrial fibrillation ablation. , Circulation: Arrhythmia and Electrophysiology, 18(1): 2025,e013351

Petzl AM, Oranefo J, Oraii A, Riley M, Lin D, Kumareswaran R, Schaller RD, Supple GE, Markman TM, Guandalini G, Hyman MC, Frankel DS, Epstein AE, Nazarian S, Garcia FC, Deo R, Callans DJ, Marchlinski FE, Dixit S. Outcomes in patients with cardiac amyloidosis undergoing catheter ablation for atrial arrhythmias. , Heart Rhythm O2, 6(8): 2025,1088-1096

Boyle T, Callans D, Deo R, Garcia F, Guandalini G, Hyman M, Lin D, Nazarian S, Riley M, Shivamurthy P, Supple G, Walsh M, Schaller R, Frankel D. Lead implantation in the setting of venous occlusion: Long-term outcomes with tunneled leads. , JACC: Clinical Electrophysiology, 11(7): 2025,1616-1618

Markman TM, Lin D, Nazarian S, van Niekerk CJ, Mirwais M, Garg L, Bode W, Smietana J, Sugrue A, Patel NA, Patel D, Ha B, Hyman MC, Riley M, Callans DJ, Deo R, Yang R, Schaller RD, Kumareswaran R, Guandalini GS, Epstein AE, Marchlinski FE, Frankel DS. Intraoperative pectoral nerve blocks during cardiac implantable electronic device procedures. , Heart Rhythm, 22(5): 2025,1264-1269

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