Gregory E. Supple, MD
he/him/his
Cardiology
Accepting new patients
Sees patients age 18 and up
Penn Heart and Vascular Center
View 1 additional location
Penn Medicine Provider

About me

  • Director, Cardiac Electrophysiology Fellowship Program
  • Associate Director, Cardiac Electrophysiology Laboratory
  • Associate Professor of Clinical Medicine (Cardiovascular Medicine)

Education and training

  • Medical School: University of Pennsylvania Health System
  • Residency: Massachusetts General Hospital
  • Fellowship: University of Pennsylvania Health System

What my patients think about me

Average Rating

749 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

November 2025
professional and pleasant
October 2025
he's a great doctor.
October 2025
very nice man. polite and respectful.
October 2025
he's great

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Dr. Supple is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Shivamurthy P, Cevasco M, Supple GE, Hanumanthu BK, Markman TM, Guandalini G, Hyman MC, Enriquez A, Kumareswaran R, Fradley MG, Deo R, See VY, Riley M, Garcia F, Nazarian S, Lin D, Frankel DS, Dixit S, Epstein AE, Callans DJ, Marchlinski FE, Schaller RD. Epicardial placement of implantable cardioverter-defibrillators in adults: Technical considerations, system performance, and clinical outcomes , Heart Rhythm: 2025,e908-e918


Zghaib T, Enriquez A, Schaller RD, Dixit S, Supple GE, Garcia FC, Callans DJ, Hyman MC, Frankel DS, Marchlinski FE, Nazarian S, Markman TM. Coronary venous ethanol infusion for treatment of refractory ventricular arrhythmias , Heart Rhythm: 2025,e682-e690


Chaumont C, Oraii A, Rodriguez-Queralto O, Petzl A, Zado E, Hanumanthu BKJ, Markman TM, Hyman MC, Tschabrunn CM, Enriquez A, Shivamurthy P, Kumareswaran R, Riley MP, Lin D, Schaller RD, Nazarian S, Callans DJ, Supple GE, Garcia FC, Frankel DS, Dixit S, Anselme F, Marchlinski FE. Sex-Related Differences in Non-Pulmonary Vein Triggers During Initial Atrial Fibrillation Ablation , JAMA Netw Open, 8: 2025,e2529527


Chaumont C, Petzl AM, Tschabrunn CM, Oraii A, Rodriguez-Queralto O, Sugrue AM, Mirwais M, Markman TM, Supple GE, Hyman MC, Nazarian S, Callans DJ, Garcia FC, Frankel DS, Anselme F, Marchlinski FE. Ablation of ventricular tachycardia from right ventricular aneurysms in patients with arrhythmogenic cardiomyopathy guided by intracardiac echocardiography , Heart Rhythm: 2025,1969-1974


Peters CJ, Supple GE. Step-by-Step Approach to Phrenic Nerve Displacement , J Cardiovasc Electrophysiol: 2025,1201-1212


Austin MA, Supple GE, Carrell S, Quinn C, Elman L, Nazarian S. Reply: Extended Cardiac Rhythm Monitoring Detects More Arrhythmias in Myotonic Dystrophy Patients , JACC Clin Electrophysiol: 2025


Oraii A, Hanumanthu BKJ, Petzl A, Liao TW, Afzalian A, Rodriguez-Queralto O, Chaumont C, Spears J, Markman TM, Hyman MC, Tschabrunn CM, Guandalini G, Enriquez A, Shivamurthy P, Kumareswaran R, Deo R, Ferrari VA, Riley MP, Lin D, Callans DJ, Supple GE, Schaller RD, Frankel DS, Garcia FC, Nazarian S, Dixit S, Marchlinski FE. Catheter ablation of atrial fibrillation in patients with cardiac amyloidosis and sarcoidosis: procedural findings and outcomes , Europace, 27: 2025,euaf100


Austin MA, Supple GE, Carrell S, Quinn C, Elman L, Nazarian S. Reply: Advancing Risk Assessment in Myotonic Muscular Dystrophy Through Translational Research and Personalized Medicine , JACC Clin Electrophysiol: 2025


Austin MA, Supple GE, Carrell S, Quinn C, Elman L, Nazarian S. Atrial Fibrillation and Flutter in a Contemporary Cohort of Patients With Myotonic Muscular Dystrophy , JACC Clin Electrophysiol: 2025,933-941


Petzl AM, Oranefo J, Oraii A, Riley M, Lin D, Kumareswaran R, Schaller RD, Supple GE, Markman TM, Guandalini G, Hyman MC, Frankel DS, Epstein AE, Nazarian S, Garcia FC, Deo R, Callans DJ, Marchlinski FE, Dixit S. Outcomes in patients with cardiac amyloidosis undergoing catheter ablation for atrial arrhythmias , Heart Rhythm O2, 6: 2025,1088-1096


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