Edward B. Lee, MD, PhD

Pathology and Laboratory Medicine
Accepting new patients
Sees patients age 18 and up
Penn Pathology and Laboratory Medicine HUP
Call 800-789-7366
Headshot of Edward B. Lee, MD, PhD
Penn Medicine Provider

About me

  • Professor of Pathology and Laboratory Medicine

My clinical expertise is in Neuropathology.

My education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: University of Pennsylvania Health System
  • Fellowship: University of Pennsylvania Health System

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Lee is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

Research

Publications

Lee Edward B, Lee Virginia M-Y, Trojanowski John Q Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration. , Nature reviews. Neuroscience, 13(1): 2011,38-50

Igaz Lionel M*, Kwong Linda K*, Lee Edward B*, Chen-Plotkin Alice, Swanson Eric, Unger Travis, Malunda Joe, Xu Yan, Winton Matthew J, Trojanowski John Q, Lee Virginia M-Y Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice. , The Journal of clinical investigation, 121(2): 2011,726-38

Liu Elaine Y, Russ Jenny, Wu Kathryn, Neal Donald, Suh Eunran, McNally Anna G, Irwin David J, Van Deerlin Vivianna M, Lee Edward B C9orf72 hypermethylation protects against repeat expansion-associated pathology in ALS/FTD. , Acta neuropathologica, 128(4): 2014,525-41

Russ Jenny, Liu Elaine Y, Wu Kathryn, Neal Donald, Suh EunRan, Irwin David J, McMillan Corey T, Harms Matthew B, Cairns Nigel J, Wood Elisabeth M, Xie Sharon X, Elman Lauren, McCluskey Leo, Grossman Murray, Van Deerlin Vivianna M, Lee Edward B Hypermethylation of repeat expanded C9orf72 is a clinical and molecular disease modifier. , Acta neuropathologica, 129(1): 2015,39-52

McMillan Corey T, Russ Jenny, Wood Elisabeth M, Irwin David J, Grossman Murray, McCluskey Leo, Elman Lauren, Van Deerlin Vivanna, Lee Edward B C9orf72 promoter hypermethylation is neuroprotective: Neuroimaging and neuropathologic evidence. , Neurology, 84(16): 2015,1622-30