Edward B. Lee, MD, PhD
Pathology and Laboratory Medicine
Accepting new patients
Sees patients age 18 and up
Penn Pathology and Laboratory Medicine HUP
Penn Medicine Provider
About me
- John Q. Trojanowski, M.D., Ph.D. Professor for Neurodegenerative Disease Research
My clinical expertise is in Neuropathology.
My education and training
- Medical School: University of Pennsylvania School of Medicine
- Residency: University of Pennsylvania Health System
- Fellowship: University of Pennsylvania Health System
Spoken languages
English
English
Insurance accepted
Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.
- Aetna Advantra Cares D-SNP
- Aetna Advantra Credit Value
- Aetna Advantra Eagle HMO
- Aetna Advantra Eagle POS
- Aetna Advantra Premier Plus PPO
- Aetna Advantra Value
- Aetna Advantra Value Plus
- Aetna APCN Plus (Multi-Tier)
- Aetna Better Health Kids (CHIP) - DH Only
- Aetna Flexible Five
- Aetna Freedom Core
- Aetna Gold
- Aetna HMO
- Aetna Philly Prime
- Aetna POS
- Aetna PPO APCN
- Aetna Premier
- Aetna Premier Plus
- Aetna Savings Plus
- Aetna Signature Administrators
- Aetna Student Health Plan PPO
- Aetna Upfront Advantage
- First Health HMO
- First Health POS
- First Health PPO
- Meritain - Aramark (Other)
- Meritain - Aramark (Pennsylvania Premier Medical Plan)
- Centivo EPO
- Cigna Healthcare EPO
- Cigna Healthcare HMO
- Cigna Healthcare POS
- Cigna Healthcare PPO
- Claim Watcher (Homestead/ INDECs) Open Access
- Clover Health Choice
- Clover Health Choice Value PPO
- Clover Health Classic HMO
- Clover Health Value
- Devoted Health Choice Giveback Pennsylvania (PPO)
- Devoted Health Choice Pennsylvania (PPO)
- Devoted Health Choice Plus Pennsylvania (PPO)
- Devoted Health Core Pennsylvania (HMO)
- Devoted Health Dual Plus Pennsylvania (HMO D-SNP)
- Devoted Health Giveback Pennsylvania (HMO)
Locations
Penn Medicine hospital privileges
- Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
- Pennsylvania Hospital: Has privileges to treat patients in the hospital.
- Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Qualifications and experience
- Pathology - Anatomic Pathology, 2009
- Pathology, Neuropathology
- 1Florida Alzheimer's Disease Research Center, National
- American Association of Neuropathologists, National
- American Society for Investigative Pathology, National
- Association for Frontotemporal Degeneration & Alzheimer's Drug Discovery Foundation, International
- International Society for Frontotemporal Dementias, International
- NIH Study Section, National
- NIH Study Section, National
- Rainwater Charitable Foundation, International
- Society for Neuroscience, International
- South Texas Alzheimer's Disease Research Center, National
Treatments and conditions
Research
Publications
Lee Edward B, Lee Virginia M-Y, Trojanowski John Q Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration. , Nature reviews. Neuroscience, 13(1): 2011,38-50
Igaz Lionel M*, Kwong Linda K*, Lee Edward B*, Chen-Plotkin Alice, Swanson Eric, Unger Travis, Malunda Joe, Xu Yan, Winton Matthew J, Trojanowski John Q, Lee Virginia M-Y Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice. , The Journal of clinical investigation, 121(2): 2011,726-38
Liu Elaine Y, Russ Jenny, Wu Kathryn, Neal Donald, Suh Eunran, McNally Anna G, Irwin David J, Van Deerlin Vivianna M, Lee Edward B C9orf72 hypermethylation protects against repeat expansion-associated pathology in ALS/FTD. , Acta neuropathologica, 128(4): 2014,525-41
Russ Jenny, Liu Elaine Y, Wu Kathryn, Neal Donald, Suh EunRan, Irwin David J, McMillan Corey T, Harms Matthew B, Cairns Nigel J, Wood Elisabeth M, Xie Sharon X, Elman Lauren, McCluskey Leo, Grossman Murray, Van Deerlin Vivianna M, Lee Edward B Hypermethylation of repeat expanded C9orf72 is a clinical and molecular disease modifier. , Acta neuropathologica, 129(1): 2015,39-52
McMillan Corey T, Russ Jenny, Wood Elisabeth M, Irwin David J, Grossman Murray, McCluskey Leo, Elman Lauren, Van Deerlin Vivanna, Lee Edward B C9orf72 promoter hypermethylation is neuroprotective: Neuroimaging and neuropathologic evidence. , Neurology, 84(16): 2015,1622-30