Devraj Basu, MD, PhD, FACS

Otorhinolaryngology
Accepting new patients
Sees patients age 15 and up
Penn Otorhinolaryngology - Head and Neck Surgery Perelman
Make an appointmentCall 800-789-7366
Headshot of Devraj Basu, MD, PhD, FACS
Penn Medicine Provider

About me

  • Associate Professor of Otorhinolaryngology: Head and Neck Surgery at the Hospital of the University of Pennsylvania

As part of a multidisciplinary team, Dr. Basu is dedicated to optimizing survival for the most serious cases of head and neck cancer cases while managing readily curable ones with the goal of minimizing lasting negative effects from treatment. He has over a decade of experience in managing the most complex head and neck cancers along with benign head and neck tumors. His practice integrates conventional surgery with endoscopic, robotic, and laser techniques to treat diseases of the mouth, throat, larynx, nose, sinuses, salivary glands, parapharyngeal space, and skin. He is also highly experienced in surgical management of thyroid and parathyroid diseases.

In addition, Dr. Basu’s NIH-funded research brings a cutting-edge molecular perspective to surgical cancer care, with particular focus on the HPV-related head and neck cancer epidemic. As a surgeon-scientist, his laboratory facilitates the use of these tumors removed from patients to advance the science of cancer therapy.

My education and training

  • Medical School: Washington University School of Medicine
  • Residency: Barnes-Jewish Hospital - Washington University, St. Louis

Watch video featuring Devraj Basu, MD, PhD, FACS on YouTube

Spoken languages

English
English

Reviews

Average Rating

181 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
April 2026
i am confused about the implication that this mass equates to an std? how is that an determination before the mass is extracted and analyzed?
Anonymous
April 2026
all together it was a great experience
Anonymous
April 2026
i meet a lot of medical providers and i felt a mutual respect with dr basu. he provided a pathway to trust.
Anonymous
February 2026
i feel i'm in good hands with my condition.

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Basu is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

Research

Publications

Sannigrahi MK, Raghav L, Rich DJ, Schrank TP, Califano JA, Lukens JN, Sun L, Morgan IM, Cohen RB, Lin A, Liu X, Brown EJ, You J, Mirabello L, Mishra SK, Shimunov D, Brody RM, Pearson AT, Gimotty PA, Diab A, Jalaly JB, Basu D. Tumor-intrinsic and immune-related features associated with treatment failure in HPV-related oropharyngeal cancer , JNCI, 117(7): 2025

Sannigrahi MK, Raghav L, Diab A, Basu D. The imprint of viral oncoproteins on the variable clinical behavior among human papilloma virus-related oropharyngeal squamous cell carcinomas , Tumour Virus Res., 18: 2024

James CD, Otoa1 RO, Youssef AH, Fontan CT, Sannigrahi MK, Windle B, Basu D, Morgan IM HPV16 genome structure analysis in oropharyngeal cancer PDXs identifies tumors with integrated and episomal genomes , Tumor Virus Res, 18: 2024

Sannigrahi M, Cao AC, Rajagopalan R, Sun L, Brody RM, Raghav L, Gimotty PA, Basu D A novel pipeline for prioritizing cancer type-specific therapeutic vulnerabilities using DepMap identifies PAK2 as a target in head and neck squamous cell carcinomas , Molecular Oncology, 18(2): 2024,336-339

Sannigrahi MK, Rajagopalan P, Lai L, Liu X, Sahu V, Nakagawa H, Jalaly JB, Brody RM, Morgan IM, Windle BE, Wang X, Gimotty PA, Kelly DP, White EA, Basu D HPV E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1alpha/ERRalpha axis , JCI Insight, 7(18): 2022

Brody RM, Shimunov D, Cohen RB, Lukens JN, Hartner L, Aggarwal C, Duvvuri U, Montone KT, Jalaly J, LiVolsi VA, Carey RM, Shanti RM, Rajasekaran K, Chalian AA, Rassekh H, Cannady SB, Newman JG, Basu D A benchmark for oncologic outcomes and model for lethal recurrence risk after transoral robotic resection of HPV-related oropharyngeal cancers , Oral Oncology, 127: 2022

Hatterschide J, Castagnino P, Kim HW, Sperry SM, Montone KT, Basu D, White EA YAP1 activation by human papillomavirus E7 promotes basal cell identity in squamous epithelia , eLife, 16: 2022,e75466

Facompre ND, Rajagopalan P, Sahu V, Pearson AT, Montone KT, James CD, Gleber-Netto FO, Weinstein GS, Jalaly J, Lin A, Rustgi AK, Nakagawa H, Califano JA, Pickering CR, White EA, Windle BE, Morgan IM, Cohen RB, Gimotty PA, Basu D. Identifying predictors of HPV-related head and neck squamous cell carcinoma progression and survival through patient-derived models. , Int J Cancer, 147(11): 2020

Harmeyer KM, Facompre ND, Herlyn M, Basu D JARID1 Histone Demethylases: Emerging Targets in Cancer , Trends Cancer, 3(10): 2017,713-725

Facompre ND, Harmeyer KM, Sole X, Kabraji S, Belden Z, Sahu V, Whelan K, Tanaka K, Weinstein GS, Montone KT, Roesch A, Gimotty PA, Herlyn M, Rustgi AK, Nakagawa H, Ramaswamy S, Basu D JARID1B Enables Transit between Distinct States of the Stem-like Cell Population in Oral Cancers , Cancer Res, 76(18): 2016,5538-49