Dawn J. Mechanic-Hamilton, PhD, ABPP
she/her/hers
Neuropsychology
Accepting new patients
Sees patients age 18 and up
Penn Memory Center
Headshot of Dawn J. Mechanic-Hamilton, PhD, ABPP
Penn Medicine Provider

About me

  • Division Chief, Neuropsychology
  • Clinical Director, Cognitive Fitness Program
  • Associate Professor of Neurology at the Hospital of the University of Pennsylvania

Education and training

  • Graduate School: Drexel University College of Nursing & Health Professions
  • Fellowship: University of Pennsylvania Health System

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Advanced Practice Provider
  • Pennsylvania Hospital: Advanced Practice Provider
  • Penn Presbyterian Medical Center: Advanced Practice Provider
Dr. Mechanic-Hamilton is a Penn Medicine provider.

Qualifications and experience

Treatments and Conditions

My research

Stites SD, Midgett S, Patel N, Halberstadter K, Schumann R, Streitz ML, Shi Y, Morris JC, Flatt J, Glover CM, Mechanic-Hamilton D Recognizing Structural and Social Determinants of Health in the Diagnosis and Care of Dementia , Dementia (London) , 25(2): 2026,237-265


Brown CA, Mundada NS, Cousins KAQ, Sadeghpour N, Lyu X, McGrew E, Korecka M, Chen-Plotkin A, Xie L, Wisse LEM, Detre JA, McMillan CT, Lee EB, Nasrallah IM, Das SR, Mechanic-Hamilton D, Yushkevich PA, Shaw LM, Wolk DA; Alzheimer’s Disease Neuroimaging Initiative. Evaluation of Copathology and Clinical Trajectories in Individuals With Tau-Clinical Mismatch , JAMA Neurol, 83: 2026,126-136


Brown CA, Mundada NS, Cousins KAQ, Sadeghpour N, Lyu X, McGrew E, Korecka M, Chen-Plotkin A, Xie L, Wisse LEM, Detre JA, McMillan CT, Lee EB, Nasrallah IM, Das SR, Mechanic-Hamilton D, Yushkevich PA, Shaw LM, Wolk DA; Alzheimer’s Disease Neuroimaging Initiative. Evaluation of Copathology and Clinical Trajectories in Individuals With Tau-Clinical Mismatch , JAMA Neurology, 83(2): 2026,126-136


Li Y, Xie L, Khandelwal P, Wisse LEM, Brown CA, Prabhakaran K, Tisdall MD, Mechanic-Hamilton D, Detre JA, Das SR, Wolk DA, Yushkevich PA Automatic Segmentation of Medial Temporal Lobe Subregions in Multi-Scanner, Multi-Modality Magnetic Resonance Imaging of Variable Quality , Hippocampus, 35(6): 2025


Sachs BC, Latham LA, Isom S, Clark LR, Craft S, Duff K, Espeland MA, Farias ST, Gaussoin SA, Goldstein FC, Hampstead BM, Jayadev S, Jicha GA, Kukull WA, Leng XI, Mechanic-Hamilton D, Neugroschl J, Papp KV, Saykin AJ, Sewell MC, Rapp SR Multi-site video-based assessment with the NACC UDS-Version 3 battery: Design and participant experience in the V-Cog study , Alzheimer's & Dementia, 21(10): 2025


Kim B, Blam K, Elser H, Xie SX, Van Deerlin VM, Penning TM, Weintraub D, Irwin DJ, Massimo LM, McMillan CT, Mechanic-Hamilton D, Wolk DA, Lee EB Ambient Air Pollution and the Severity of Alzheimer Disease Neuropathology , JAMA Neurology, 82: 2025,1153-1161


Brown CA, Mundada NS, Cousins KAQ, Sadeghpour N, Lyu X, McGrew E, Korecka M, Chen-Plotkin A, Xie L, Wisse LEM, Detre JA, McMillan CT, Lee EB, Nasrallah IM, Das SR, Mechanic-Hamilton D, Yushkevich PA, Shaw LM; Alzheimer’s Disease Neuroimaging Initiative; Wolk DA. Tau-Clinical Mismatch Identifies Individuals with Co-Pathology and Predicts Clinical Trajectory , medRxiv: 2025


Stites SD, Kuz C, Halberstadter K, Humphreys V, Cousins KAQ, Mechanic-Hamilton D Societal Gender Norms and Their Influence on Late Life Cognition , Neurodegener Dis : 2025


Sanderson-Cimino M, Gross AL, Gaynor LS, Paolillo EW, Saloner R, Albert MS, Apostolova FG, Boersema B, Boxer AL, Boeve BF, Casaletto KB, Hallgarth SR, Diaz VE, Clark LR, Maillard P, Eloyan A, Farias ST, Gonzales MM, Hammers DB, Joie R, Cobigo Y, Wolf A, Hampstead BM, Mechanic-Hamilton D, Miller BL, Rabinovici GD, Ringman JM, Rosen HJ, Ryman SG, Prestopnik JL, Salmon DP, Smith GE, DeCarli C, Rajan KB, Jin LW, Hinman J, Johnson DK, Harvey D, Fornage M, Kramer JH, Staffaroni AM. Development and validation of a harmonized memory score for multicenter Alzheimer's disease and related dementia research , medRxiv: 2025


Halberstadter K, Humphreys V, Rovere R, Liebenberg E, Mechanic-Hamilton D Technology Behaviors and Sentiments Among Cognitively Normal Older Adults using the Mobile Cognitive App Performance Platform , 53rd Annual Meeting of the International Neuropsychological Society : 2025