David S. Frankel, MD
Cardiology
Accepting new patients
Sees patients age 18 and up
Penn Heart and Vascular Center
View 1 additional location
Make an appointmentCall 215-615-4949
Penn Medicine Provider

About me

  • Director, Cardiac Electrophysiology Laboratory
  • Professor of Medicine (Cardiovascular Medicine) at the Hospital of the University of Pennsylvania

I treat the entire range of heart rhythm disorders, from bradycardias to tachycardias, including supraventricular tachycardia, atrial fibrillation, premature ventricular complexes and ventricular tachycardia. I implant cardiac devices, including subcutaneous cardiac rhythm monitors, pacemakers and defibrillators. I also perform the entire range of catheter ablations. My goal is to work with you to find the best treatment for your condition.

Education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: Massachusetts General Hospital
  • Fellowship: University of Pennsylvania School of Medicine
  • Fellowship: Hospital of the University of Pennsylvania

What my patients think about me

Average Rating

957 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

November 2025
very helpful
October 2025
great doctor
October 2025
seemed very thorough and understood my concerns.
October 2025
he has amazing bedside manner and really knows his stuff!!

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Dr. Frankel is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Boyle TA, Frankel DS. Severe acute kidney injury from limited pulsed field ablation , Heart Rhythm: 2025

Shivamurthy P, Cevasco M, Supple GE, Hanumanthu BK, Markman TM, Guandalini G, Hyman MC, Enriquez A, Kumareswaran R, Fradley MG, Deo R, See VY, Riley M, Garcia F, Nazarian S, Lin D, Frankel DS, Dixit S, Epstein AE, Callans DJ, Marchlinski FE, Schaller RD. Epicardial placement of implantable cardioverter-defibrillators in adults: Technical considerations, system performance, and clinical outcomes , Heart Rhythm: 2025

Zghaib T, Enriquez A, Schaller RD, Dixit S, Supple GE, Garcia FC, Callans DJ, Hyman MC, Frankel DS, Marchlinski FE, Nazarian S, Markman TM. Coronary venous ethanol infusion for treatment of refractory ventricular arrhythmias , Heart Rhythm: 2025

Rekapalli P, Oraii A, Heintz J, Dixit S, Epstein AE, Frankel DS, Hyman M, Lin D, Markman T, Messé SR, Nazarian S, Cucchiara B, Schaller RD, See VY, Yang W, Kasner SE, Marchlinski FE, Deo R. Detection and Significance of Nonsustained Ventricular Tachycardia in a Post-Stroke Population , JACC Clin Electrophysiol: 2025

Nguyen O, Wiedrick J, Massera D, Adlestein E, Frejat S, Castrichini M, Alsidawi S, Giudicessi JR, Geske JB, Carrick RT, Madrazo J, Dellise N, Zenker MA, Boyle TA, Reza N, Owens AT, Frankel DS, Hundal P, Tajik J, Galazka P, Lewontin M, Ayers M, Wong T, Flanagan M, Mitter SS, Kanwal A, Bilen O, Baghdadi S, Shah H, Kvapil J, Roldan P, Berenbom L, Jesurum J, Tootill D, Siqueira-Benzow A, Harper M, Saleh D, Choudhury L, Valenta I, Lang M, Phelan DM, Prizand D, Lakdawala N, Ho CY, Liang LW, Weiner SD, Ravi S, Abuzaid AS, Makkiya M, Markowitz JS, Sherrid M, Masri A. Incidence and Outcomes of Atrial Fibrillation and Systolic Dysfunction in Patients Receiving Mavacamten for Obstructive Hypertrophic Cardiomyopathy: A Multicenter Study , medRxiv: 2025

Chaumont C, Oraii A, Rodriguez-Queralto O, Petzl A, Zado E, Hanumanthu BKJ, Markman TM, Hyman MC, Tschabrunn CM, Enriquez A, Shivamurthy P, Kumareswaran R, Riley MP, Lin D, Schaller RD, Nazarian S, Callans DJ, Supple GE, Garcia FC, Frankel DS, Dixit S, Anselme F, Marchlinski FE. Sex-Related Differences in Non-Pulmonary Vein Triggers During Initial Atrial Fibrillation Ablation , JAMA Netw Open, 8: 2025,e2529527

Enriquez A, Frankel DS. Atrial Fibrillation Ablation in Heart Failure With Mitral Regurgitation: 2 Benefits for the Price of 1 , JACC Clin Electrophysiol: 2025

Shaik A, Frankel DS, Khurshid S. When Close Is Not Close Enough: Cardiomyopathy After Deep Septal Pacing , J Cardiovasc Electrophysiol: 2025

Markson FE, Abe TA, Frankel DS, Schaller RD. Incidence of Pacing-Induced Cardiomyopathy Among Patients With Leadless Versus Transvenous Ventricular Pacemakers , Circ Arrhythm Electrophysiol: 2025

Tan JL, Chirinos J, Patel D, Jagasia D, Hyman MC, Guandalini GS, Nazarian S, Lin D, Supple G, Frankel DS, Callans DJ, Marchlinski FE, Ren JF, Markman TM. Intracardiac echocardiography for left ventricular diastolic function assessment during atrial fibrillation ablation , J Interv Card Electrophysiol: 2025