David A. Mankoff, MD, PhD

Radiology
Accepting new patients
Sees patients age 18 and up
Penn Medicine Provider

About me

  • Vice Chair for Research, Radiology
  • Matthew J. Wilson Professor of Research Radiology

My education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: University of Washington Hospitals

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Chester County Hospital: Has privileges to treat patients in the hospital.
Dr. Mankoff is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

Research

Publications

Mankoff, D., Balogova, S., Dunnwald, L., Dehdashti, F., DeVries, E., Evangelista, L., Van Kruchten, M., Vaz, S. C., Fowler, A., Linden, H., Ulaner, G. A. Summary: SNMMI Procedure Standard/EANM Practice Guideline for Estrogen Receptor Imaging of Patients with Breast Cancer Using 16alpha-[(18)F]Fluoro-17beta-Estradiol PET , J Nucl Med, 65(2): 2024,221-223


Sreekumar, A., Blankemeyer, E., Sterner, C. J., Pan, T. C., Pant, D. K., Acolatse, S., Turkistani, H., Belka, G. K., Nayak, A., Carlin, S. D., Assenmacher, C. A., Sellmyer, M. A., Mankoff, D. A., Chodosh, L. A. Residual Breast Cancer Cells Co-opt SOX5-Driven Endochondral Ossification to Maintain Dormancy , Cancer Discov, 16(4): 2026,781-799


Lee, H., Sarkar, S., Xu, K., Martorano, P., Pham, J., Park, P. S. U., King, A. P., Lee, H. S., Mankoff, D. A., Pryma, D. A., Sellmyer, M. A. Influence of Subcellular Localization on the Cytotoxicity of Targeted alpha-Therapy , J Nucl Med, 67(3): 2026,429-437


Choi, H., Gupta, M., Sengupta, A., Furth, E. E., Hensley, C., Weljie, A. M., Lee, H., Lu, Y. T., Pantel, A., Mankoff, D., Zhou, R. Disruption of redox balance in glutaminolytic triple negative breast cancer by inhibition of glutaminase and glutamate export , Neoplasia, 61: 2025,101136


Kwon, D., Li, E. J., Dulal, C., Daube-Witherspoon, M., Viswanath, V., Young, A. J., Damani, R. A., Hou-Liu, J., McDonald, E. S., Mankoff, D. A., Karp, J. S., Pantel, A. R. Dual-Tracer Imaging on a Long-Axial-Field-of-View PET: A Proof-of-Principle Study with [(18)F]FGln and [(18)F]FDG , J Nucl Med, 66(7): 2025,1149-1152


Hensley, C. T., Padakanti, P., Damani, R., Dulal, C., Choi, H., Li, S., Cao, J., Lee, H., Pantel, A., Li, E., Mankoff, D., Zhou, R. L-5-[(11)C]-glutamine PET of breast cancer: Preclinical studies in mouse models , Nucl Med Biol, 150-151: 2025,109092


Zhou, R., Choi, H., Cao, J., Pantel, A., Gupta, M., Lee, H. S., Mankoff, D. (18)F-Fluciclovine PET Imaging of Glutaminase Inhibition in Breast Cancer Models , J Nucl Med, 64(1): 2023,131-136


Chen, A. W., Zeballos Torrez, C. R., Peterson, L. M., Muzi, M., Specht, J. M., Cohen, E. A., Linden, H. M., Kontos, D., Mankoff, D. A. Novel 4D radiomics applied to dynamic FES PET images to improve prediction of breast cancer response to ER-targeted therapy , Eur J Nucl Med Mol Imaging, 53(5): 2026,3128-3139


Pantel, A. R., Gitto, S. B., Makvandi, M., Kim, H., Medvedv, S., Weeks, J. K., Torigian, D. A., Hsieh, C. J., Ferman, B., Latif, N. A., Tanyi, J. L., Martin, L. P., Lanzo, S. M., Liu, F., Cao, Q., Mills, G. B., Doot, R. K., Mankoff, D. A., Mach, R. H., Lin, L. L., Simpkins, F. [18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study , Clin Cancer Res, 29(8): 2023,1515-1527


McDonald, E. S., Doot, R. K., Pantel, A. R., Farwell, M. D., Mach, R. H., Maxwell, K. N., Mankoff, D. A. Positron Emission Tomography Imaging of Poly-(Adenosine Diphosphate-Ribose) Polymerase 1 Expression in Breast Cancer: A Nonrandomized Clinical Trial , JAMA Oncol: 2020