David R. Lynch, MD, PhD
Neurology
Independent provider
Accepting new patients
Sees patients age 18 and up
Penn Neuroscience Center - Neurology
Make an appointmentCall 800-789-7366

About me

  • Professor of Neurology
  • Professor of Neurology in Pediatrics

Education and training

  • Medical School: Johns Hopkins University School of Medicine
  • Residency: Hospital of the University of Pennsylvania
  • Fellowship: Hospital of the University of Pennsylvania

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Dr. Lynch is an independent physician who is not employed by Penn Medicine.

Qualifications and experience

Treatments and Conditions

My research

Rummey C, Thomas-Black G, Garcia-Moreno H, Lynch DR, Abeti R, Arisoy H, Heslegrave A, Zetterberg H, Giunti P; European Friedreich's Ataxia Consortium for Translational Studies (EFACTS). Increase of Plasma Biomarkers in Friedreich's Ataxia: Potential Insights into Disease Pathology , Movement disorders, 409: 2025,1863-1873.

Shiraishi DH, Saha S, Adanyeguh IM, Cocozza S, Corben LA, Deistung A, Delatycki MB, Dogan I, Gaetz W, Georgiou-Karistianis N, Graf S, Grisoli M, Henry PG, Jarola GM, Joers JM, Langkammer C, Lenglet C, Li J, Lobo CC, Lock EF, Lynch DR, Mareci TH, Martinez ARM, Monti S, Nigri A, Pandolfo M, Reetz K, Roberts TP, Romanzetti S, Rudko DA, Scaravilli A, Schulz JB, Subramony SH, Timmann D, França MC Jr, Harding IH, Rezende TJR; TRACK-FA Neuroimaging Consortium. Automated Deep Learning-based Segmentation of the Dentate Nucleus Using Quantitative Susceptibility Mapping MRI , Radiol Artif Intell .: 2025,e240478.

Georgiou-Karistianis N, Corben LA, Lock EF, Bujalka H, Adanyeguh I, Corti M, Deelchand DK, Delatycki MB, Dogan I, Farmer J, França MC Jr, Gabay AS, Gaetz W, Harding IH, Joers J, Lax MA, Li J, Lynch DR, Mareci TH, Martinez ARM, Pandolfo M, Papoutsi M, Parker RG, Reetz K, Rezende TJR, Roberts TP, Romanzetti S, Rudko DA, Saha S, Schulz JB, Subramony SH, Supramaniam VG, Lenglet C, Henry PG. Neuroimaging biomarkers for Friedreich ataxia: a cross-sectional analysis of TRACK-FA , Ann Neurol, 98(2): 2025,386-397

Perlman S, Zhang S, Setyawan J, Yang H, Jiang A, Hua Q, Boudreau J, Khan S, Bajaj A, Lynch DR, Lawson R. The clinical burden of Friedreich ataxia in the United States: A retrospective claims database analysis , J Neurol Sci, 475: 2025,123594.

Yameogo P, Aguilar S, Prakash TP, Rigo F, Lynch DR, Napierala JS, Napierala M. Antisense oligonucleotide therapy for patients with Friedreich's ataxia carrying the c.165+5G>C splicing mutation. , Mol Ther Nucleic Acids. , 36(3): 2025,102617

Gunther, K, Profeta, V, Keita, M, Park, C, Wells, M, Sharma, S, Schadt, K Lynch, D. R. Safety Monitoring of Omaveloxolone in Friedreich Ataxia: Results from one year of clinical treatment , Neurology and Therapy, 14(3): 2025,1105-1114

Mercado Ayón, E., Talgo, E., Flatley, L., Coulman, J., Lynch, D. R. Neurochemical Alterations in the Cerebellum in Friedreich’s Ataxia Mouse Models. , Experimental Neurology, 386: 2025,115176

Joseph, D.J., Mercado-Ayon, E., Flatley, L., Viaene, A. N., Hordeaux, J., Marsh, E. D., Lynch, D. R. Functional Characterization of Parallel fiber-Purkinje Cell Synapses in two Friedreich’s Ataxia Mouse Models , Cerebellum, 24(2): 2025,42

Eshaghi, K., Rao, P., Shen, M., Lynch, D. R. Genetic and Phenotypic Variability in Siblings with Friedreich Ataxia , Neurology Genetics, 11(1): 2025,doi.org/10.1212/NXG.0000000000200234

Lynch, D.R., Subramony, S.H., Lin, K.Y., Mathews, K., Perlman, S., Yoon, G., Rummey, C. Characterization of cardiac-onset initial presentation in Friedreich Ataxia , Pediatric Cardiology., 46(2): 2025,379-382