David L. Jaffe, MD
Gastroenterology
Accepting new patients
Sees patients age 18 and up
Penn Gastroenterology Perelman
Penn Medicine Provider

About me

  • Professor of Clinical Medicine (Gastroenterology)

Education and training

  • Medical School: Harvard Medical School
  • Residency: Massachusetts General Hospital
  • Fellowship: Massachusetts General Hospital

What my patients think about me

Average Rating

322 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

October 2025
thorough
October 2025
dr jaffe is a careful listener
October 2025
dr. jaffe's experience and knowledge were very reassuring to us. we feel confident entrusting my husband's care to him.
October 2025
dr jaffe takes the best care of me, i feel confident in him because he is thoughtful and thorough, he hears me and i follow his suggestions. he is kind, caring and brilliant.

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Jaffe is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Katona BW, Shukla A, Hu W, Nyul T, Dudzik C, Arvanitis A, Clay D, Dungan M, Weber M, Tu V, Hao F, Gan S, Chau L, Buchner AM, Falk GW, Jaffe DL, Ginsberg GG, Palmer S, Zhan X, Patterson AD, Bittinger K, Ni, J Microbiota and metabolite-based prediction tool for colonic polyposis with and without a known genetic driver , Gut Microbes, 17(1): 2025,2474141


Kumar S, Chandrasekhara V, Kochman ML, Ahmad N, Attalla S, Ho IK, Jaffe DL, Lee PJ, Panganamamula KV, Saumoy M, Fortuna D, Ginsberg GG Ligation-assisted endoscopic mucosal resection for esophageal granular cell tumors is safe and effective , Dis Esophagus, 10(1093): 2020,27


Thompson CC, Abu Dayyeh BK, Kushnir V, Kushner RF, Jirapinyo P, Schorr AB, Aronne LJ, Amaro A, Jaffe DL, Schulman AR, Early D, Stein AC, Sharaiha R, Edmundowicz SA, Bohning JM, Jensen MD, Shukla AP, Apovian C, Kim DW, Tran D, Zarrinpar A, Ryan MB, Young M, Lowe A, Haas M, Goldsmith H, McCrea J, Sullivan S Aspiration therapy for the treatment of obesity: 4-year results of a multicenter randomized controlled trial , Surg Obes Relat Dis, 15(8): 2019,1348-54


Dai SC, Goldberg D, Agarwal A, Ma GK, Yam C, Ahmad NA, Ginsberg GG, Jaffe DL, Kochman ML, Olthoff KM, Chandrasekhara V. Endoscopic Therapy is Effective for Recurrent Anastomotic Biliary Strictures after Orthotopic Liver Transplantation. , Annals of Hepatology, 16(6): 2017,924-931


Banc-Husu AM1, Ahmad NA, Chandrasekhara V, Ginsberg GG, Jaffe DL, Kochman ML, Rajala MW, Mamula P. Therapeutic Endoscopy for the Control of Nonvariceal Upper Gastrointestinal Bleeding in Children: A Case Series. , J Pediatr Gastroenterol Nutr. , 64(4): 2017,e88-91


Thompson CC, Dayyeh BKA, Kushner R, Sullivan S, Schorr AB, Amaro A, Apovia CM, Fullum T, Zarrinpar A, Jensen MD, Stein AC, Edmundowicz S, Kahaleh M, Ryou M, Bohning JM, Ginsberg GG, Huang C, Tran DD, Glaser JP, Martin JA, Jaffe DL, Farraye FA, Ho SB, Kumar N, Harakal D, Young M, Thomas CE, Shukla AP, Ryan MB, Haas M, Goldsmith H, McCrea J, Aronne LJ Percutaneous Gastrostomy Device for the Treatment of Class II and Class III Obesity: Results of a Randomized Controlled Trial , Am J Gastroenterol, 112(3): 2017,447-57


Nikhil R. Thiruvengadam, MD, Kimberly A. Forde, MD MHS, Gene K. Ma, MD, Nuzhat Ahmad, MD, Vinay Chandrasekhara, MD, Gregory G. Ginsberg, MD, Immanuel K. Ho, MD, David Jaffe, MD, Kashyap V. Panganamamula, MD, Michael, L. Kochman, MD Rectal Indomethacin Reduces Pancreatitis in High- and Low-Risk Patients Undergoing Endoscopic Retrograde Cholangiopancreatography , Gastroenterology, 151(2): 2016,288-297


Enestvedt BK, Tofani C, Lee DY, Abraham M, Shah P, Chandrasekhara V, Ginsberg G, Long W, Ahmad N, Jaffe DL, Mamula P, and Kochman ML Endoscopic retrograde cholangiopancreatography in the pediatric population is safe and efficacious , Journal of Pediatric Gastroenterology and Nutrition , 57(5): 2013,649


Ryan McConnell, Stephen Kim, Nuzhat A. Ahmad, Gary W. Falk, Kimberly A. Forde, Gregory G. Ginsberg, David L. Jaffe, George Makar, William B. Long, Kashyap Panganamamula, Michael L. Kochman "Poor Discriminatory Function for Endoscopy Skills on a Computer-Based Simulator” , Gastrointestinal Endoscopy , 76(5): 2012,993


Kim S, Spencer G, Makar GA, Ahmad NA, Jaffe DL, Ginsberg GG, Kuchenbecker KJ, Kochman ML. Lack of a discriminatory function for endoscopy skills on a computer-based simulator , Surgical Endoscopy, 24(12): 2010,3008-3015


View all publications