David C. Fajgenbaum, MD, MBA, MSc

Dorottya Laczko, Vinodh Pillai, Dale Frank, Joshua D Brandstadter, David C Fajgenbaum How I diagnose Castleman disease , American Journal of Clinical Pathology., 165(3): 2026

Elliott W Sharp, Nicholas Fragola, Charlotte Blewitt, Matthew Goddeeris, Lee Lancashire, Charlie Hempstead, David C Fajgenbaum Quantify unmet medical need across the disease landscape - A large language model-based methodology , PLOS Medicine., 23(3): 2026

Marcello DeLuca, Nico Matentzoglu, Elliott Sharp, Jane Li, Charlie Hempstead, May Lim, Piotr Kaniewski, E. Kathleen Carter, Kushal Koirala, Elvin Ding, Laurens Vijnck, Pascal Brokmeier, Sabrina Toro, Kevin Schaper, Jacques Vergine, Olivia Li, Tudor I. Oprea, David C. Fajgenbaum, Christopher Bizon, Melissa Haendel, Alexander Tropsha. Medicines, Diseases, Indications, and Contraindications (MeDIC): a foundational resource to support drug repurposing , Nucleic Acids Research., 54(D1): 2026,D1477-D1487

Sally Nijim, Ania Korsunska, Joseph Zinski, Sarah E. Bolden, Mary Zuccato, Mileva Repasky, David C. Fajgenbaum. Rare Disease Drug Repurposing , JAMA Network Open., 8(5): 2025,e258330

Tomoka Haratake, Midori Filiz Nishimura, Asami Nishikori, Michael V. Gonzalez, Daisuke Ennishi, You Cheng Lai, Sayaka Ochi, Manaka Tsunoda, David C. Fajgenbaum, Frits van Rhee, Shuji Momose, Yasuharu Sato. The Involvement of PI3K-Akt Signaling in the Clinical and Pathological Findings of Idiopathic Multicentric Castleman Disease-Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis, and Organomegaly and Not Otherwise Specified Subtypes , Modern Pathology., 38(8): 2025,100782

Steven Rowe, Mariam Goubran, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Bridget Austin, Kathleen McNicholas, Marley Blommers, Junyan Shi, Lisa K. Peterson, Lusia Sepiashvili, Andre Mattman, Joshua D. Brandstadter, David C. Fajgenbaum, Luke Y. C. Chen. Ferritin, C-Reactive Protein, and Soluble CD25 Distinguish TAFRO From HLH , American Journal of Hematology., 100(12): 2025,2421-2425

Dorottya Laczko, Patricia Tsao, Ruth-Anne Pai, Joseph Zinski, Michael V. Gonzalez, Melanie D. Mumau, Tobias Raabe, Hiromi Muramatsu, Norbert Pardi, Taku Kambayashi, David C. Fajgenbaum. A patient-derived CABIN1 mutation recapitulates features of idiopathic multicentric Castleman disease in a mouse model , Blood Advances., 9(24): 2025,6534-6537

Midori Filiz Nishimura, Tomoka Haratake, Yoshito Nishimura, Asami Nishikori, Remi Sumiyoshi, Hideki Ujiie, Yuri Kawahara, Tomohiro Koga, Masao Ueki, Dorottya Laczko, Eric Oksenhendler, David C. Fajgenbaum, Frits van Rhee, Atsushi Kawakami, Yasuharu Sato. International Consensus Histopathological Criteria for Subtyping Idiopathic Multicentric Castleman Disease Based on Machine Learning Analysis , American Journal of Hematology., 100(9): 2025,1502-1512

Allan Feng, Michael V. Gonzalez, Muge Kalaycioglu, Xihui Yin, Melanie D. Mumau, Saishravan Shyamsundar, Mateo Bustamante Sarmiento, Sarah E. Chang, Dhingra Shaurya, Tea Dodig-Crnkovic, Jochen M. Schwenk, Tarun Garg, Kazuyuki Yoshizaki, Frits van Rhee, David C. Fajgenbaum, Paul J. Utz Common connective tissue disorder and anti-cytokine autoantibodies are enriched in idiopathic multicentric castleman disease patients , Frontiers in Immunology, 16(1528465): 2025

Melanie D. Mumau, Michael V. Gonzalez, Chunyu Ma, Abiola H. Irvine, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Luke Y.C. Chen, David Koslicki, David C. Fajgenbaum Identifying and Targeting TNF Signaling in Idiopathic Multicentric Castleman's Disease , The New England Journal of Medicine., 392(6): 2025,616-618