Dana DiRenzo, MD, MHS
Rheumatology
Accepting new patients
Sees patients age 18 and up
Penn Rheumatology University City
Schedule onlineCall 215-662-4333
Headshot of Dana DiRenzo, MD, MHS
Penn Medicine Provider

About me

  • Assistant Professor of Clinical Medicine (Rheumatology)

Dr. Dana D. DiRenzo, MD, MHS, is an Assistant Professor of Clinical Medicine in the Division of Rheumatology at the University of Pennsylvania and serves as Chief of Rheumatology at Penn Presbyterian Medical Center. She is a member of the Penn Sjogren's center and director of the Penn Musculoskeletal Ultrasound program. Dr. DiRenzo earned her MD from Temple University School of Medicine and completed her Internal Medicine residency at the University of Maryland Hospital, followed by a Rheumatology fellowship at Johns Hopkins Hospital, where she also earned her Master’s in Health Sciences. Her clinical expertise includes inflammatory arthritis, Sjögren’s syndrome, and musculoskeletal ultrasound, and her research centers on patient-reported outcomes, quality of life, mindfulness, and health-related quality of life tools—she leads the Prospective Longitudinal Study to Understand Sjögren’s (PLUS) and serves as a co-chair for the OMERACT Sjögren’s Working Group. 

Education and training

  • Medical School: Temple University School of Medicine
  • Residency: University of Maryland Medical Center
  • Fellowship: Johns Hopkins Hospital

What my patients think about me

Average Rating

550 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

February 2026
excellent provider
January 2026
i already recommended her to two people. i fully trust her judgement and know she has my best interests in mind when she makes care decisions.
January 2026
she's the best!
January 2026
expert care, very thorough.

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. DiRenzo is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Lee AYS, Zembrzuska H, Franke KB, Gordon R, Franke EF, Kumble L, Boderman B, Pelkas C, Hitchcock ME, Cornec D, Rischmueller M, Bowman SJ, Seror R, McCoy SS, DiRenzo D. Patients' perspectives of living with Sjögren disease: A systematic review of qualitative studies from the OMERACT Sjögren disease working group. , Semin Arthritis Rheum, 77: 2026,152929

Hunt, C, Letzen, J, DiRenzo, D, Gould, N, Sibinga, E, Vetter, M, Webb, C, Finan, P, Mun, CJ The self-efficacy for regular meditation practice scale (SERMS): Development and psychometric validation. , Journal of Health Psychology, 30(7): 2025,1550-1562

Tison A, Jousse-Joulin S, Consigny M, Moog P, Hofauer B, Hachulla E, Lamotte C, Morel J, Mouterde G, Milic V, Bootsma H, Stel A, Fisher BA, Maybury M, Baer A, DiRenzo D, Kim HR, Min HK, Lee SS, Choi SE, Alegria GC, Boisramé S, Guellec D, Cornec D, Quéré B, Jonsson M, Hammenfors D, Saraux A, Devauchelle-Pensec V Are ultrasound salivary parenchymal lesions more severe in primary Sjögren patients with a longer disease duration? A cross-sectional study , Rheumatology (Oxford), 64(6): 2025,3739-3746

Tison A, Jousse-Joulin S, Consigny M, Moog P, Hofauer B, Hachulla E, Lamotte C, Morel J, Mouterde G, Milic V, Bootsma H, Stel A, Fisher BA, Maybury M, Baer A, DiRenzo D, Kim HR, Min HK, Lee SS, Choi SE, Alegria GC, Boisramé S, Guellec D, Cornec D, Quéré B, Jonsson M, Hammenfors D, Saraux A, Devauchelle-Pensec V. Are ultrasound salivary parenchymal lesions more severe in primary Sjögren patients with a longer disease duration? A cross-sectional study. , Rheumatology (Oxford): 2024

Dayno R, George M, Blum M, DeQuattro K, Kolasinski S, DiRenzo D Description of Self-Efficacy for Managing Symptoms and Emotions in a Large Rheumatology Clinic Population , Clin Exp Rheumatol, 42(11): 2024,2175-2182

Romich E, Saygin D, DiRenzo D, Mecoli CA, de Groot I, Lodin K, Regardt M, Sarver C, Kim JY, Park JK, Beer K, Needham M, Alexanderson H, Christopher-Stine L, de Visser M, Raaphorst J. Construct validity of PROMIS pain interference, fatigue, and physical function as patient-reported outcomes in adults with idiopathic inflammatory myopathies: An international study from the OMERACT myositis working group , Semin Arthritis Rheum, 68: 2024,152534

Saygin D, Alexanderson H, DiRenzo D, Raaphorst J, de Visser M, Ren D, Regardt M, de Groot I, Sarver C, Kim JY, Lodin K, Beer K, Needham M, Park JK, Christopher-Stine L, Mecoli CA The impact of pain on daily activities in patients with idiopathic inflammatory myopathies: Report from the OMERACT myositis working group. , Semin Arthritis Rheum, 67: 2024,152476

DiRenzo D, Barrett FS, Perin J, Darrah E, Christopher-Stine L, Griffiths RR Impact of Psilocybin on Peripheral Cytokine Production , Psychedelic Medicine, 2(2): 2024,109-115

Wallwork RS, Kotzin JJ, Cappelli LC, Mecoli C, Bingham CO 3rd, Wigley FM, Wilson PC, DiRenzo DD, Shah AA Immune checkpoint inhibitor therapy in patients with cancer and pre-existing systemic sclerosis. , Semin Arthritis Rheum, 4(67): 2024

Quéré B, Saraux A, Carvajal-Alegria G, Guellec D, Mouterde G, Lamotte C, Hammenfors D, Jonsson M, Choi SE, Hong-Ki M, Stel A, Fisher BA, Maybury M, Hofauer B, Ferro F, Milic V, Direnzo D, Devauchelle-Pensec V, Jousse-Joulin S Reliability Exercise of Ultrasound Salivary Glands in Sjögren's Disease: An International Web Training Initiative , Rheumatol Ther, 11(2): 2024,411-423