Clyde E. Markowitz, MD

Neurology
Accepting new patients
Sees patients age 18 and up
Penn Neuroscience Center - Neurology
Schedule onlineCall 800-789-7366
Penn Medicine Provider

About me

  • Director, Multiple Sclerosis Center at Penn
  • Associate Professor of Neurology at the Hospital of the University of Pennsylvania

My education and training

  • Medical School: Columbia University
  • Residency: NewYork–Presbyterian Hospital
  • Fellowship: NewYork-Presbyterian/Columbia University Medical Center

Spoken languages

English
English

Reviews

Average Rating

817 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
May 2026
he listens and pays attention
Anonymous
May 2026
my doctor didn't freak out when lesions were growing in my brain. instead he allowed his patience to show that my medication was actually working
Anonymous
April 2026
clyde markowitz is a fabulous provider
Anonymous
April 2026
very helpful

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Markowitz is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

Research

Publications

Fox EJ, Markowitz C, Applebee A, Montalban X, Wolinsky JS, Belachew S, Fiore D, Pei J, Musch B, Giovannoni G Ocrelizumab reduces progression of upper extremity impairment in patients with primary progressive multiple sclerosis: Findings from the phase III randomized ORATORIO trial. , Mult Scler. : 2018

Cehelyk EK, Harvey DY, Grubb ML, Jalel R, El-Sibai MS, Markowitz CE, Berger JR, Hamilton RH, Chahin S Uncovering the association between fatigue and fatigability in multiple sclerosis using cognitive control. , Mult Scler Relat Disord. , 27: 2018,269-275

Fox E, Markowitz C, Applebee A, et al Effect of ocrelizumab on upper limb function in patients with primary progressive multiple sclerosis (PPMS) in the oratorio study (ENCORE) , J Neurol Neurosurg Psychiatry, 89(A14): 2018

Sahin N, Selouan R, Markowitz CE, Melhem ER, Bilello M Limbic pathway lesions in patients with multiple sclerosis. , Acta Radiol., 57(3): 2016,341-7

Salim Chahin, MD; Deborah Miller, PhD; Reiko Sakai; James Wilson; Clyde Markowitz, MD; Dina Jacobs, MD; Ari Green, MD; Peter A. Calabresi, MD; Elliot M. Frohman, MD; Steven Galetta, MD; Laura Balcer, MD, MSCE: Fatigue in Multiple Sclerosis: Relation to Quantitative Neurologic and Visual Outcomes. , Multiple Sclerosis and related disorders: 2015

Jose Torres, Amy Pruitt, Laura Balcer, Steven Galetta, Clyde Markowitz, Nabila Dahodwala Analysis of the treatment of neuromyelitis optica , Journal of the Neurological Sciences , 351(1): 2015

Salim Chahin, Deborah Miller, Reiko E. Sakai, James A. Wilson, Teresa Frohman, Clyde Markowitz, Dina Jacobs, Ari Green, Peter A. Calabresi, Elliot M. Frohman, Steven L. Galetta, Laura J. Balcer Relation of quantitative Visual and neurologic outcomes to fatigue in multiple sclerosis , Multiple Sclerosis and Related Disorders, 4(4): 2015

Edward Fox, Barbara Green, Clyde Markowitz, Ronald Murray, Andrew D Goodman, Stephen J Glenski, Pippa Loupe, Jo Nita Cogburn The effect of scheduled antibody testing on treatment patterns in interferon-treated patients with multiple sclerosis , BMC Neurology , 14(1): 2014

Patricia K Coyle, Bruce A Cohen, Thomas Leist, Clyde Markowitz, Merrikay Oleen-Burkey, Marc Schwartz, Mark J Tullman, Howard Zwibel Therapy optimization in multiple sclerosis: a prospective observational study of therapy compliance and outcomes , BMC Neurology , 14(1): 2014

Miller Aaron E, Cohen Bruce A, Krieger Stephen C, Markowitz Clyde E, Mattson David H, Tselentis Helen N Constructing an adaptive care model for the management of disease-related symptoms throughout the course of multiple sclerosis--performance improvement CME. , Multiple sclerosis (Houndmills, Basingstoke, England): 2013