Christopher Alan Brown, MD, PhD
Neurology
Accepting new patients
Sees patients age 18 and up
Penn Memory Center
Headshot of Christopher Alan Brown, MD, PhD
Penn Medicine Provider

About me

  • Instructor A of Neurology

Education and training

  • Medical School: University of Kentucky College of Medicine
  • Residency: Hospital of the University of Pennsylvania

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Brown is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Brown CA, Mundada NS, Cousins KAQ, Sadeghpour N, Lyu X, McGrew E, Korecka M, Chen-Plotkin A, Xie L, Wisse LEM, Detre JA, McMillan CT, Lee EB, Nasrallah IM, Das SR, Mechanic-Hamilton D, Yushkevich PA, Shaw LM, Wolk DA; Alzheimer’s Disease Neuroimaging Initiative. Evaluation of Copathology and Clinical Trajectories in Individuals With Tau-Clinical Mismatch , JAMA Neurol, 83: 2026,126-136


Lyu X, Mundada NS, Brown CA, Sadeghpour N, McGrew E, Xie L, Li Y, Wuestefeld A, Duong MT, Cook P, Gee J, Nasrallah IM, Chen-Plotkin AS, Shaw LM, Mechanic-Hamilton D, Wisse LEM, Yushkevich PA, Das SR, Wolk DA, for the Alzheimer’s Disease Neuroimaging Initiative Medial temporal lobe Tau-Neurodegeneration mismatch from MRI and plasma biomarkers , Brain: 2026


Brown CA, Cousins KAQ, Korecka M, McGrew E, Chen-Plotkin A, Detre JA, McMillan CT, Lee EB, Das SR, Mechanic-Hamilton D, Yushkevich PA, Nasrallah IM, Shaw LM, Alzheimer’s Disease Neuroimaging Initiative, Wolk DA Temporal Modeling of Amyloid and Tau Trajectories in Alzheimer’s Disease using PET and Plasma Biomarkers , Ann Neurol: 2026


Cousins KAQ, Boyle R, Morse C, Verma A, Brown CA, O'Brien KS, Serper M, Dehghani N; Penn Medicine BioBank; McMillan CT, Lee EB, Shaw LM, Wolk DA. Electronic Health Records to Test Multimorbidity Influences to Plasma Biomarker Interpretation for Alzheimer's Disease , Ann Neurol: 2025


Mundada NS, Lyu X, Brown CA, Sadeghpour N, McGrew E, Xie L, Cook PA, Gee J, Yushkevich PA, Das SR, Wolk DA; Alzheimer's Disease Neuroimaging Initiative. Enrichment of patients with concomitant limbic-predominant age-related TDP-43 encephalopathy (LATE) on the Alzheimer's disease continuum using hippocampal volume , Alzheimers Dement, 21(12): 2025,e70970


Shakibajahromi B, Dolui S, Brown CA, Taghvaei M, Sadaghiani S, Khandelwal P, Das S, Yushkevich PA, Nasrallah IM, Xie SX, Wolk DA, Detre JA. Clinical correlates of perfusion and diffusion MRI metrics in cognitively unimpaired older adults , J Cereb Blood Flow Metab: 2025


Brown CA, Das SR, Detre JA, Nasrallah IM, Yushkevich PA, McMillan CT, Wolk DA. Fully individualized models for cross-sectional and longitudinal network-based tau spread , Imaging Neurosci (Camb), 3: 2025,IMAG


Li Y, Xie L, Khandelwal P, Wisse LEM, Brown CA, Prabhakaran K, Tisdall MD, Mechanic-Hamilton D, Detre JA, Das SR, Wolk DA, Yushkevich PA. Automatic Segmentation of Medial Temporal Lobe Subregions in Multi-Scanner, Multi-Modality Magnetic Resonance Imaging of Variable Quality , Hippocampus, 35(6): 2025,e70036


Sreepada LP, Brown CA, Das SR, Yushkevich PA, Wolk DA, McMillan CT Biological age acceleration in Alzheimer's disease modulates relative cortical to medial temporal lobe neurodegeneration , Neurobiol Aging, 153: 2025,21-29


Cousins KAQ, Korecka M, Wan Y, Vulaj A, Brown C, Tropea TF, Lee EB, Tosun D, Landau SM, Okonkwo OC, Mindt MR, Weiner MW, Irwin DJ, Wolk DA, Shaw LM Comparison of plasma p-tau217/Aβ42, p-tau217, and Aβ42/Aβ40 biomarkers by race to detect Alzheimer's disease , Alzheimers Dement, 21(8): 2025,e70469


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