Penn Medicine Provider
Rheumatology
Chris T Derk, MD, MS
4.9
(622)
Accepting new patients
Sees patients age 18 and up
Penn Rheumatology Perelman
View 1 additional location
Schedule onlineCall 215-662-2454

About me

  • Professor of Clinical Medicine (Rheumatology)

Specialize in Systemic Sclerosis ( Scleroderma) and Scleroderma like illnesses; Raynaud's and related conditions; Autoimmune Connective tissue disorders. 

Recognized by America's Top Doctors for 2017

Recognized in Philadelphia magazine's annual Top Docs issues from 2017-2024

Education and training

  • Medical School: Jefferson Medical College
  • Residency: Abington Memorial Hospital
  • Fellowship: Thomas Jefferson University Hospital

What my patients think about me

Average Rating
4.9

622 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

August 2025
5.0
5.0
he's a very good physician
July 2025
5.0
5.0
i understand what he was talking about
July 2025
5.0
5.0
i like how the dr listens to me.. and remembers my history-
July 2025
5.0
5.0
excellent doctor, helped me understand my situation

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Derk is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Mehmetoglu E, Mummadisetty A, Chatzitofis A, Parperis K, Sandorfi N, Derk CT A systematic review of prevalence and predictors of depression in systemic sclerosis based on the CES-D, BDI and PHQ-9 self-assessment questionnaires , Clin Rheumatol: 2025

Hajnoczky N, Levin LS, Sandorfi N, Derk CT Long-term outcomes of vascular grafting of medium-sized vessels of wrist and hand in systemic sclerosis patients with medication refractory Raynaud's , J Scleroderma Relat Disord : 2025

Parperis K, Papachristodoulou M, Derk C, Psarelis S, Voskarides K, Chatzittofis A. Post-traumatic stress disorder and systemic lupus erythematosus: insights from a systematic review. , Rheumatology: 2025

Aguila T, Madan R, Palmer MB, Derk CT Zebra bodies in kidney biopsy: Drug-induced phospholipidosis in patient with Systemic Lupus Erythematosus , J Rheumatol : 2025

Papchristodoulou E; Kakkoulis L; Chopra R; Derk CT, Parperis K Clinical Features and Treatment Outcomes in Aseptic Abscess Syndrome: A Systematic Review of 104 Cases , ACR Convergence : 2025

GRASP study group Functional NOTCH4 Variants Drive Vasculopathy and Fibrosis in Systemic Sclerosis. , ACR Convergence: 2025

Parperi K, Costi E, Philippou S, Hadi M, Derk CT Efficacy of disease modifying antirheumatic drugs in the treatment of granulomatous mastitis: a systematic review , Rheumatol Int, 44(11): 2024,2371-79

GRASP study group Rare variants in the IL1RAP gene implicate the IL-1 signaling pathway in the pathogenesis of systemic sclerosis in African and European ancestries. , ACR annual scientific meeting, Washington DC: 2024

GRASP study group Admixture mapping and gene-based analysis identifies rare variants in genes in the IL-13 and TGF beta signaling pathways in African Americans with systemic sclerosis , ACR annual scientific meeting, Washington DC: 2024

GRASP study Group TCR motifs identify unique clones in African Americans with systemic sclerosis , ACR annual Scientific meeting, Washington DC : 2024

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